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Large Atomistic Models (LAMs) have undergone remarkable progress recently, emerging as universal or fundamental representations of the potential energy surface defined by the first-principles calculations of atomistic systems. However, our…

Recent years have witnessed a surge in the development of protein foundation models, significantly improving performance in protein prediction and generative tasks ranging from 3D structure prediction and protein design to conformational…

Quantitative Methods · Quantitative Biology 2024-10-08 Fei Ye , Zaixiang Zheng , Dongyu Xue , Yuning Shen , Lihao Wang , Yiming Ma , Yan Wang , Xinyou Wang , Xiangxin Zhou , Quanquan Gu

Many learning-based approaches have difficulty scaling to unseen data, as the generality of its learned prior is limited to the scale and variations of the training samples. This holds particularly true with 3D learning tasks, given the…

Computer Vision and Pattern Recognition · Computer Science 2020-12-15 Mingyue Yang , Yuxin Wen , Weikai Chen , Yongwei Chen , Kui Jia

Developing Foundation Models for medical image analysis is essential to overcome the unique challenges of radiological tasks. The first challenges of this kind for 3D brain MRI, SSL3D and FOMO25, were held at MICCAI 2025. Our solution…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Pedro M. Gordaliza , Jaume Banus , Benoît Gérin , Maxence Wynen , Nataliia Molchanova , Jonas Richiardi , Meritxell Bach Cuadra

Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities in diverse reasoning tasks, yet their application to complex physics reasoning remains underexplored. Physics reasoning presents unique challenges, requiring…

Computation and Language · Computer Science 2025-05-23 Song Dai , Yibo Yan , Jiamin Su , Dongfang Zihao , Yubo Gao , Yonghua Hei , Jungang Li , Junyan Zhang , Sicheng Tao , Zhuoran Gao , Xuming Hu

Artificial Intelligence methods to solve continuous- control tasks have made significant progress in recent years. However, these algorithms have important limitations and still need significant improvement to be used in industry and real-…

Artificial Intelligence · Computer Science 2017-07-05 Hamid Mirzaei , Mona Fathollahi , Tony Givargis

Robots excel at avoiding obstacles but struggle to traverse complex 3-D terrain with cluttered large obstacles. By contrast, insects like cockroaches excel at doing so. Recent research in our lab elucidated how locomotor transitions emerge…

Robotics · Computer Science 2025-09-26 Jonathan Mi , Yaqing Wang , Chen Li

Current trends in scientific imaging are challenged by the emerging need of integrating sophisticated machine learning with Big Data analytics platforms. This work proposes an in-memory distributed learning architecture for enabling…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-01 A. Panousopoulou , S. Farrens , K. Fotiadou , A. Woiselle , G. Tsagkatakis , J-L. Starck , P. Tsakalides

We introduce a general-purpose framework for interconnecting scientific simulation programs using a homogeneous, unified interface. Our framework is intrinsically parallel, and conveniently separates all component numerical modules in…

Instrumentation and Methods for Astrophysics · Physics 2015-06-04 Simon Portegies Zwart , Steve McMillan , Arjen van Elteren , Inti Pelupessy , Nathan de Vries

Current foundation models for 3D shapes excel at global tasks (retrieval, classification) but transfer poorly to local part-level reasoning. Recent approaches leverage vision and language foundation models to directly solve dense tasks…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Souhail Hadgi , Bingchen Gong , Ramana Sundararaman , Emery Pierson , Lei Li , Peter Wonka , Maks Ovsjanikov

Physics problem-solving is a challenging domain for AI models, requiring integration of conceptual understanding, mathematical reasoning, and interpretation of physical diagrams. Existing evaluations fail to capture the full breadth and…

Artificial Intelligence · Computer Science 2026-02-12 Lintao Wang , Encheng Su , Jiaqi Liu , Pengze Li , Jiabei Xiao , Wenlong Zhang , Xinnan Dai , Xi Chen , Yuan Meng , Lei Bai , Wanli Ouyang , Shixiang Tang , Aoran Wang , Xinzhu Ma

We introduce PHYSICS, a comprehensive benchmark for university-level physics problem solving. It contains 1297 expert-annotated problems covering six core areas: classical mechanics, quantum mechanics, thermodynamics and statistical…

Artificial Intelligence · Computer Science 2026-05-22 Kaiyue Feng , Yilun Zhao , Yixin Liu , Tianyu Yang , Chen Zhao , John Sous , Arman Cohan

Large Language Models (LLMs) have shown impressive performance in domains such as mathematics and programming, yet their capabilities in physics remain underexplored and poorly understood. Physics poses unique challenges that demand not…

This work presents PanMatch, a versatile foundation model for robust correspondence matching. Unlike previous methods that rely on task-specific architectures and domain-specific fine-tuning to support tasks like stereo matching, optical…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Yongjian Zhang , Longguang Wang , Kunhong Li , Ye Zhang , Yun Wang , Liang Lin , Yulan Guo

Agentic large language models are proposed as autonomous code generators for scientific computing, yet their reliability in high-stakes problems remains unclear. Developing computational scientific software from natural-language queries…

Multiagent Systems · Computer Science 2025-12-02 Vansh Sharma , Venkat Raman

Numerical physics has gained a lot of importance in the last decade, its efficiency being motivated and sustained by the growth of computational power. This paper presents a concept that is to be developed in the next few years: OpenPh.…

Digital Libraries · Computer Science 2011-06-28 George Milescu , Gabriel Noaje , Florin Pop

We explore the potential application of quantum annealing to address the protein structure problem. To this end, we compare several proposed ab initio protein folding models for quantum computers and analyze their scaling and performance…

Quantum Physics · Physics 2026-04-27 Timon Scheiber , Matthias Heller , Andreas Giebel

While traditional tree-based ensemble methods have long dominated tabular tasks, deep neural networks and emerging foundation models have challenged this primacy, yet no consensus exists on a universally superior paradigm. Existing…

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Partial differential equations (PDEs) are central to scientific modeling. Modern workflows increasingly rely on learning-based components to support model reuse, inference, and integration across large computational processes. Despite the…

Machine Learning · Computer Science 2026-02-20 Yilong Dai , Shengyu Chen , Ziyi Wang , Xiaowei Jia , Yiqun Xie , Vipin Kumar , Runlong Yu