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Automatic examination of thin-prep cytologic test (TCT) slides can assist pathologists in finding cervical abnormality for accurate and efficient cancer screening. Current solutions mostly need to localize suspicious cells and classify…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Zhenrong Shen , Maosong Cao , Sheng Wang , Lichi Zhang , Qian Wang

Cervical intraepithelial neoplasia (CIN) grade of histopathology images is a crucial indicator in cervical biopsy results. Accurate CIN grading of epithelium regions helps pathologists with precancerous lesion diagnosis and treatment…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Yuan Xue , Qianying Zhou , Jiarong Ye , L. Rodney Long , Sameer Antani , Carl Cornwell , Zhiyun Xue , Xiaolei Huang

Rectal cancer is one of the most common diseases and a major cause of mortality. For deciding rectal cancer treatment plans, T-staging is important. However, evaluating the index from preoperative MRI images requires high radiologists'…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Saeko Sasuga , Akira Kudo , Yoshiro Kitamura , Satoshi Iizuka , Edgar Simo-Serra , Atsushi Hamabe , Masayuki Ishii , Ichiro Takemasa

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Automation in medical imaging is quite challenging due to the unavailability of annotated datasets and the scarcity of domain experts. In recent years, deep learning techniques have solved some complex medical imaging tasks like disease…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Soumyajyoti Dey , Sukanta Chakraborty , Utso Guha Roy , Nibaran Das

One of the key impediments for developing and assessing robust medical imaging algorithms is limited access to large-scale datasets with suitable annotations. Synthetic data generated with plausible physical and biological constraints may…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Christopher Wiedeman , Anastasiia Sarmakeeva , Elena Sizikova , Daniil Filienko , Miguel Lago , Jana G. Delfino , Aldo Badano

Cervical cancer remains a significant health challenge, with high incidence and mortality rates, particularly in transitioning countries. Conventional Liquid-Based Cytology(LBC) is a labor-intensive process, requires expert pathologists and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Love Panta , Suraj Prasai , Karishma Malla Vaidya , Shyam Shrestha , Suresh Manandhar

Objective: Cytology plays a crucial role in lung cancer diagnosis. Pulmonary cytology involves cell morphological characterization in the specimen and reporting the corresponding findings, which are extremely burdensome tasks. In this…

Image and Video Processing · Electrical Eng. & Systems 2026-04-23 Atsushi Teramoto , Ayano Michiba , Yuka Kiriyama , Tetsuya Tsukamoto , Kazuyoshi Imaizumi , Hiroshi Fujita

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

The ThinPrep Cytologic Test (TCT) is the most widely used method for cervical cancer screening, and the sample quality directly impacts the accuracy of the diagnosis. Traditional manual evaluation methods rely on the observation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Lanlan Kang , Jian Wang , Jian QIn , Yiqin Liang , Yongjun He

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yuntao Shou , Xiangyong Cao , Qian Zhao , Deyu Meng

While medical image segmentation is an important task for computer aided diagnosis, the high expertise requirement for pixelwise manual annotations makes it a challenging and time consuming task. Since conventional data augmentations do not…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Dwarikanath Mahapatra , Ankur Singh

Image synthesis is used to generate synthetic CTs (sCTs) from on-treatment cone-beam CTs (CBCTs) with a view to improving image quality and enabling accurate dose computation to facilitate a CBCT-based adaptive radiotherapy workflow. As…

Image and Video Processing · Electrical Eng. & Systems 2023-12-05 Chelsea A. H. Sargeant , Edward G. A. Henderson , Dónal M. McSweeney , Aaron G. Rankin , Denis Page

We propose a novel framework for controllable pathological image synthesis for data augmentation. Inspired by CycleGAN, we perform cycle-consistent image-to-image translation between two domains: healthy and pathological. Guided by a…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Khrystyna Faryna , Kevin Koschmieder , Marcella M. Paul , Thomas van den Heuvel , Anke van der Eerden , Rashindra Manniesing , Bram van Ginneken

AI for cancer detection encounters the bottleneck of data scarcity, annotation difficulty, and low prevalence of early tumors. Tumor synthesis seeks to create artificial tumors in medical images, which can greatly diversify the data and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Yuxiang Lai , Xiaoxi Chen , Angtian Wang , Alan Yuille , Zongwei Zhou

Objective Renal cancer is a common malignancy and a major cause of cancer-related deaths. Computed tomography (CT) is central to early detection, staging, and treatment planning. However, the growing CT workload increases radiologists'…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Renjie Liang , Zhengkang Fan , Jinqian Pan , Chenkun Sun , Bruce Daniel Steinberg , Russell Terry , Jie Xu

Multi-phase CT is widely adopted for the diagnosis of kidney cancer due to the complementary information among phases. However, the complete set of multi-phase CT is often not available in practical clinical applications. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Kwang-Hyun Uhm , Seung-Won Jung , Moon Hyung Choi , Sung-Hoo Hong , Sung-Jea Ko

The development of clinical-grade artificial intelligence in pathology is limited by the scarcity of diverse, high-quality annotated datasets. Generative models offer a potential solution but suffer from semantic instability and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Xianchao Guan , Zhiyuan Fan , Yifeng Wang , Fuqiang Chen , Yanjiang Zhou , Zengyang Che , Hongxue Meng , Xin Li , Yaowei Wang , Hongpeng Wang , Min Zhang , Heng Tao Shen , Zheng Zhang , Yongbing Zhang

Anomaly detection in visual data refers to the problem of differentiating abnormal appearances from normal cases. Supervised approaches have been successfully applied to different domains, but require an abundance of labeled data. Due to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-29 Dejan Stepec , Danijel Skocaj
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