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Synthesizing a subject-specific pathology-free image from a pathological image is valuable for algorithm development and clinical practice. In recent years, several approaches based on the Generative Adversarial Network (GAN) have achieved…

Image and Video Processing · Electrical Eng. & Systems 2022-03-30 Yunlong Zhang , Xin Lin , Yihong Zhuang , LiyanSun , Yue Huang , Xinghao Ding , Guisheng Wang , Lin Yang , Yizhou Yu

Synthesizing medical images remains challenging due to limited annotated pathological data, modality domain gaps, and the complexity of representing diffuse pathologies such as liver cirrhosis. Existing methods often struggle to maintain…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Onkar Susladkar , Gayatri Deshmukh , Yalcin Tur , Gorkhem Durak , Ulas Bagci

As a pragmatic data augmentation tool, data synthesis has generally returned dividends in performance for deep learning based medical image analysis. However, generating corresponding segmentation masks for synthetic medical images is…

Image and Video Processing · Electrical Eng. & Systems 2023-03-23 Xiaodan Xing , Giorgos Papanastasiou , Simon Walsh , Guang Yang

Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

Cone-beam computed tomography (CBCT) images are problematic in clinical medicine because of their low contrast and high artifact content compared with conventional CT images. Although there are some studies to improve image quality, in…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

Data scarcity and privacy concerns limit the availability of high-quality medical images for public use, which can be mitigated through medical image synthesis. However, current medical image synthesis methods often struggle to accurately…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Wenting Chen , Pengyu Wang , Hui Ren , Lichao Sun , Quanzheng Li , Yixuan Yuan , Xiang Li

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

Synthetic tumors in medical images offer controllable characteristics that facilitate the training of machine learning models, leading to an improved segmentation performance. However, the existing methods of tumor synthesis yield…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Hongxu Yang , Edina Timko , Levente Lippenszky , Vanda Czipczer , Lehel Ferenczi

Cervical cancer is the seventh most common cancer among all the cancers worldwide and the fourth most common cancer among women. Cervical cytopathology image classification is an important method to diagnose cervical cancer. Manual…

Computer Vision and Pattern Recognition · Computer Science 2022-06-03 Wanli Liu , Chen Li , Ning Xu , Tao Jiang , Md Mamunur Rahaman , Hongzan Sun , Xiangchen Wu , Weiming Hu , Haoyuan Chen , Changhao Sun , Yudong Yao , Marcin Grzegorzek

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Currently there is strong interest in data-driven approaches to medical image classification. However, medical imaging data is scarce, expensive, and fraught with legal concerns regarding patient privacy. Typical consent forms only allow…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 John T. Guibas , Tejpal S. Virdi , Peter S. Li

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

Accurate lesion segmentation in whole-body PET/CT scans is crucial for cancer diagnosis and treatment planning, but limited datasets often hinder the performance of automated segmentation models. In this paper, we explore the potential of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Lap Yan Lennon Chan , Chenxin Li , Yixuan Yuan

Currently, high-fidelity text-to-image models are developed in an accelerating pace. Among them, Diffusion Models have led to a remarkable improvement in the quality of image generation, making it vary challenging to distinguish between…

Computer Vision and Pattern Recognition · Computer Science 2024-11-21 Ziyue Zeng , Haoyuan Liu , Dingjie Peng , Luoxu Jing , Hiroshi Watanabe

In real-world clinical practice, electrocardiograms (ECGs) are often captured and shared as photographs. However, publicly available ECG data, and thus most related research, relies on digital signals. This has led to a disconnect in which…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Xiaoyu Wang , Ramesh Nadarajah , Zhiqiang Zhang , David Wong

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Hematoxylin and Eosin stained histopathology image analysis is essential for the diagnosis and study of complicated diseases such as cancer. Existing state-of-the-art approaches demand extensive amount of supervised training data from…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Le Hou , Ayush Agarwal , Dimitris Samaras , Tahsin M. Kurc , Rajarsi R. Gupta , Joel H. Saltz

Biomedical datasets are often constrained by stringent privacy requirements and frequently suffer from severe class imbalance. These two aspects hinder the development of accurate machine learning models. While generative AI offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Jan Carreras Boada , Rao Muhammad Umer , Carsten Marr

We present an image translation approach to generate augmented data for mitigating data imbalances in a dataset of histopathology images of colorectal polyps, adenomatous tumors that can lead to colorectal cancer if left untreated. By…

Image and Video Processing · Electrical Eng. & Systems 2019-10-15 Jerry Wei , Arief Suriawinata , Louis Vaickus , Bing Ren , Xiaoying Liu , Jason Wei , Saeed Hassanpour

We propose an image synthesis mechanism for multi-sequence prostate MR images conditioned on text, to control lesion presence and sequence, as well as to generate paired bi-parametric images conditioned on images e.g. for generating…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Shaheer U. Saeed , Tom Syer , Wen Yan , Qianye Yang , Mark Emberton , Shonit Punwani , Matthew J. Clarkson , Dean C. Barratt , Yipeng Hu