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Deep learning models often require large amounts of data for training, leading to increased costs. It is particularly challenging in medical imaging, i.e., gathering distributed data for centralized training, and meanwhile, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Zhenyu Tang , Shaoting Zhang , Xiaosong Wang

Motivation: Computational methods are essential to extract actionable information from raw sequencing data, and to thus fulfill the promise of next-generation sequencing technology. Unfortunately, computational tools developed to call…

Semi-supervised learning utilizes insights from unlabeled data to improve model generalization, thereby reducing reliance on large labeled datasets. Most existing studies focus on limited samples and fail to capture the overall data…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Xiuzhen Guo , Lianyuan Yu , Ji Shi , Na Lei , Hongxiao Wang

The breakthrough in Deep Learning neural networks has transformed the use of AI and machine learning technologies for the analysis of very large experimental datasets. These datasets are typically generated by large-scale experimental…

Machine Learning · Computer Science 2021-10-26 Jeyan Thiyagalingam , Mallikarjun Shankar , Geoffrey Fox , Tony Hey

We perform differential expression analysis of high-throughput sequencing count data under a Bayesian nonparametric framework, removing sophisticated ad-hoc pre-processing steps commonly required in existing algorithms. We propose to use…

Applications · Statistics 2017-05-04 Siamak Zamani Dadaneh , Xiaoning Qian , Mingyuan Zhou

Input data preprocessing is a common bottleneck when concurrently training multimedia machine learning (ML) models in modern systems. To alleviate these bottlenecks and reduce the training time for concurrent jobs, we present Seneca, a data…

Operating Systems · Computer Science 2025-11-19 Omkar Desai , Ziyang Jiao , Shuyi Pei , Janki Bhimani , Bryan S. Kim

Large-scale vision models like SAM have extensive visual knowledge, yet their general nature and computational demands limit their use in specialized tasks like medical image segmentation. In contrast, task-specific models such as U-Net++…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Yuchen Mao , Hongwei Li , Yinyi Lai , Giorgos Papanastasiou , Peng Qi , Yunjie Yang , Chengjia Wang

Bayesian modelling enables us to accommodate complex forms of data and make a comprehensive inference, but the effect of partial misspecification of the model is a concern. One approach in this setting is to modularize the model, and…

Methodology · Statistics 2026-03-18 Yang Liu , Robert J. B. Goudie

Sparse deep learning has become a popular technique for improving the performance of deep neural networks in areas such as uncertainty quantification, variable selection, and large-scale network compression. However, most existing research…

Machine Learning · Statistics 2023-10-06 Mingxuan Zhang , Yan Sun , Faming Liang

The rapid advancement of single-cell ATAC sequencing (scATAC-seq) technologies holds great promise for investigating the heterogeneity of epigenetic landscapes at the cellular level. The amplification process in scATAC-seq experiments often…

Genomics · Quantitative Biology 2024-08-28 Lei Huang , Lei Xiong , Na Sun , Zunpeng Liu , Ka-Chun Wong , Manolis Kellis

In this paper we develop a statistical theory and an implementation of deep learning models. We show that an elegant variable splitting scheme for the alternating direction method of multipliers optimises a deep learning objective. We allow…

Machine Learning · Statistics 2015-09-22 Nicholas G. Polson , Brandon T. Willard , Massoud Heidari

This paper makes two contributions to Bayesian machine learning algorithms. Firstly, we propose stochastic natural gradient expectation propagation (SNEP), a novel alternative to expectation propagation (EP), a popular variational inference…

Bayesian mixture models are widely used for clustering of high-dimensional data with appropriate uncertainty quantification. However, as the dimension of the observations increases, posterior inference often tends to favor too many or too…

Methodology · Statistics 2022-11-22 Noirrit Kiran Chandra , Antonio Canale , David B. Dunson

The exploration of selected single nucleotide polymorphisms (SNPs) to identify genetic diversity between different sequencing population pools (Pool-seq) is a fundamental task in genetic research. As underlying sequence reads and their…

Genomics · Quantitative Biology 2021-01-05 Julia Siekiera , Stefan Kramer

To improve the physical understanding and the predictions of complex dynamic systems, such as ocean dynamics and weather predictions, it is of paramount interest to identify interpretable models from coarsely and off-grid sampled…

Computational Physics · Physics 2021-05-04 Gert-Jan Both , Georges Tod , Remy Kusters

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Single-cell RNA sequencing (scRNA-seq) data are important for studying the laws of life at single-cell level. However, it is still challenging to obtain enough high-quality scRNA-seq data. To mitigate the limited availability of data,…

Quantitative Methods · Quantitative Biology 2024-03-06 Erpai Luo , Minsheng Hao , Lei Wei , Xuegong Zhang

While deep learning models have become the predominant method for medical image segmentation, they are typically not capable of generalizing to unseen segmentation tasks involving new anatomies, image modalities, or labels. Given a new…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Victor Ion Butoi , Jose Javier Gonzalez Ortiz , Tianyu Ma , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

We present FasterSeg, an automatically designed semantic segmentation network with not only state-of-the-art performance but also faster speed than current methods. Utilizing neural architecture search (NAS), FasterSeg is discovered from a…

Computer Vision and Pattern Recognition · Computer Science 2020-01-20 Wuyang Chen , Xinyu Gong , Xianming Liu , Qian Zhang , Yuan Li , Zhangyang Wang

In this work, we develop a method named Twinning, for partitioning a dataset into statistically similar twin sets. Twinning is based on SPlit, a recently proposed model-independent method for optimally splitting a dataset into training and…

Machine Learning · Statistics 2022-02-17 Akhil Vakayil , V. Roshan Joseph
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