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Mathematical modelling is a widely used approach to understand and interpret clinical trial data. This modelling typically involves fitting mechanistic mathematical models to data from individual trial participants. Despite the widespread…

We address a fundamental issue in the nonparametric inference for systems of interacting particles: the identifiability of the interaction functions. We prove that the interaction functions are identifiable for a class of first-order…

Statistics Theory · Mathematics 2020-09-01 Zhongyang Li , Fei Lu , Mauro Maggioni , Sui Tang , Cheng Zhang

Consider a Gaussian nonparametric regression problem having both an unknown mean function and unknown variance function. This article presents a class of difference-based kernel estimators for the variance function. Optimal convergence…

Statistics Theory · Mathematics 2009-09-29 Lawrence D. Brown , M. Levine

We consider the problem of estimating an arbitrary smooth functional of $k \geq 1 $ distribution functions (d.f.s.) in terms of random samples from them. The natural estimate replaces the d.f.s by their empirical d.f.s. Its bias is…

Statistics Theory · Mathematics 2010-08-03 C. S. Withers , S. Nadarajah

Mutual information (MI) is one of the most general ways to measure relationships between random variables, but estimating this quantity for complex systems is challenging. Denoising diffusion models have recently set a new bar for density…

Machine Learning · Computer Science 2025-11-20 Longxuan Yu , Xing Shi , Xianghao Kong , Tong Jia , Greg Ver Steeg

This paper is a survey of recent contributions on estimation in stochastic differential equations with mixed-effects. These models involve N stochastic differential equations with common drift and diffusion functions but random parameters…

Statistics Theory · Mathematics 2020-09-17 Maud Delattre

We consider the reduction of parametric families of linear dynamical systems having an affine parameter dependence that differ from one another by a low-rank variation in the state matrix. Usual approaches for parametric model reduction…

Numerical Analysis · Mathematics 2019-12-25 Christopher Beattie , Serkan Gugercin , Zoran Tomljanovic

The paper discusses inference techniques for semiparametric models based on suitable versions of inference functions. The text contains two parts. In the first part, we review the optimality theory for non-parametric models based on the…

Statistics Theory · Mathematics 2020-11-17 Rodrigo Labouriau

This paper introduces a family of recursively defined estimators of the parameters of a diffusion process. We use ideas of stochastic algorithms for the construction of the estimators. Asymptotic consistency of these estimators and…

Statistics Theory · Mathematics 2016-08-16 Jaime A. Londoño

We study approximations of evolving probability measures by an interacting particle system. The particle system dynamics is a combination of independent Markov chain moves and importance sampling/resampling steps. Under global regularity…

Probability · Mathematics 2011-12-12 Andreas Eberle , Carlo Marinelli

We propose a non-parametric extrapolation method based on constrained Gaussian processes for configuration interaction methods. Our method has many advantages: (i) applicability to small data sets such as results of {\it ab initio} methods,…

Nuclear Theory · Physics 2020-08-06 Sota Yoshida

This paper is concerned with general nonlinear regression models where the predictor variables are subject to Berkson-type measurement errors. The measurement errors are assumed to have a general parametric distribution, which is not…

Statistics Theory · Mathematics 2009-08-21 Liqun Wang

The assessment of the probability of a rare event with a naive Monte-Carlo method is computationally intensive, so faster estimation or variance reduction methods are needed. We focus on one of these methods which is the interacting…

Statistics Theory · Mathematics 2020-11-06 H. Chraibi , A. Dutfoy , T. Galtier , J. Garnier

We study a minimax risk of estimating inverse functions on a plane, while keeping an estimator is also invertible. Learning invertibility from data and exploiting an invertible estimator are used in many domains, such as statistics,…

Statistics Theory · Mathematics 2023-12-27 Akifumi Okuno , Masaaki Imaizumi

In the need for low assumption inferential methods in infinite-dimensional settings, Bayesian adaptive estimation via a prior distribution that does not depend on the regularity of the function to be estimated nor on the sample size is…

Methodology · Statistics 2014-09-23 Catia Scricciolo

Consider discrete time observations (X_{\ell\delta})_{1\leq \ell \leq n+1}$ of the process $X$ satisfying $dX_t= \sqrt{V_t} dB_t$, with $V_t$ a one-dimensional positive diffusion process independent of the Brownian motion $B$. For both the…

Methodology · Statistics 2007-12-25 Fabienne Comte , Valentine Genon-Catalot , Yves Rozenholc

Data attribution for generative models seeks to quantify the influence of individual training examples on model outputs. Existing methods for diffusion models typically require access to model gradients or retraining, limiting their…

Machine Learning · Computer Science 2025-10-17 Yutian Zhao , Chao Du , Xiaosen Zheng , Tianyu Pang , Min Lin

In this paper, we study a parabolic reaction diffusion system with constraints that model biofilm growth. Within a unified framework encompassing multiple numerical schemes, we derive the first general convergence rates for approximating…

Numerical Analysis · Mathematics 2025-11-05 Yahya Alnashri

We consider the statistical properties of interaction parameter estimates obtained by the direct coupling analysis (DCA) approach to learning interactions from large data sets. Assuming that the data are generated from a random background…

Data Analysis, Statistics and Probability · Physics 2017-04-07 Yingying Xu , Erik Aurell , Jukka Corander , Yoshiyuki Kabashima

We study the nonparametric estimation for the intensity of Poisson random measure in jump-diffusion CIR model based on the low frequency observations. This is given in terms of the minimization of norms on a nonempty, closed and convex…

Statistics Theory · Mathematics 2016-03-10 Wei Xu