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Several recent works seek to develop foundation models specifically for medical applications, adapting general-purpose large language models (LLMs) and vision-language models (VLMs) via continued pretraining on publicly available biomedical…

Computation and Language · Computer Science 2024-11-21 Daniel P. Jeong , Saurabh Garg , Zachary C. Lipton , Michael Oberst

Continual learning (CL) in large language models (LLMs) is an evolving domain that focuses on developing efficient and sustainable training strategies to adapt models to emerging knowledge and achieve robustness in dynamic environments. Our…

Computation and Language · Computer Science 2025-02-13 Çağatay Yıldız , Nishaanth Kanna Ravichandran , Nitin Sharma , Matthias Bethge , Beyza Ermis

The entry of large language models (LLMs) into research and commercial spaces has led to a trend of ever-larger models, with initial promises of generalisability, followed by a widespread desire to downsize and create specialised models…

Computation and Language · Computer Science 2024-02-19 Niall Taylor , Upamanyu Ghose , Omid Rohanian , Mohammadmahdi Nouriborji , Andrey Kormilitzin , David Clifton , Alejo Nevado-Holgado

Recently, the increasing demand for superior medical services has highlighted the discrepancies in the medical infrastructure. With big data, especially texts, forming the foundation of medical services, there is an exigent need for…

Computation and Language · Computer Science 2024-07-17 Yuanhe Tian , Ruyi Gan , Yan Song , Jiaxing Zhang , Yongdong Zhang

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

The rise of large language models (LLMs) has created a significant disparity: industrial research labs with their computational resources, expert teams, and advanced infrastructures, can effectively fine-tune LLMs, while individual…

Real-world model deployments demand strong performance on narrow domains where data is often scarce. Typically, practitioners finetune models to specialize them, but this risks overfitting to the domain and forgetting general knowledge. We…

The current generation of large language models (LLMs) is typically designed for broad, general-purpose applications, while domain-specific LLMs, especially in vertical fields like medicine, remain relatively scarce. In particular, the…

Using prompted language models as classifiers enables classification in domains with limited training data, but misses some of the robustness and performance benefits that fine-tuning can bring. We study whether training on multiple…

Artificial Intelligence · Computer Science 2026-05-13 Sam Martin , Fabien Roger

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

Large Language Models (LLMs) exploit fine-tuning as a technique to adapt to diverse goals, thanks to task-specific training data. Task specificity should go hand in hand with domain orientation, that is, the specialization of an LLM to…

Computation and Language · Computer Science 2023-09-20 Teodoro Baldazzi , Luigi Bellomarini , Stefano Ceri , Andrea Colombo , Andrea Gentili , Emanuel Sallinger

Masked Language Modeling (MLM) pre-training is one of the primary ways to initialize Neural Information Retrieval (IR) models prior to retrieval fine-tuning. However, studies show that MLM pre-trained models have limited readiness and…

Information Retrieval · Computer Science 2026-05-05 Hiun Kim , Tae Kwan Lee , Taeryun Won

Neural language models (LMs) are vulnerable to training data extraction attacks due to data memorization. This paper introduces a novel attack scenario wherein an attacker adversarially fine-tunes pre-trained LMs to amplify the exposure of…

Computation and Language · Computer Science 2024-09-04 Myung Gyo Oh , Hong Eun Ahn , Leo Hyun Park , Taekyoung Kwon

Nowadays, billions of people engage in communication and express their opinions on the internet daily. Unfortunately, not all of these expressions are friendly or compliant, making content moderation an indispensable task. A common approach…

Machine Learning · Computer Science 2024-03-08 Huan Ma , Changqing Zhang , Huazhu Fu , Peilin Zhao , Bingzhe Wu

Large Language Models (LLMs) for public use require continuous pre-training to remain up-to-date with the latest data. The models also need to be fine-tuned with specific instructions to maintain their ability to follow instructions…

Computation and Language · Computer Science 2024-10-15 Ishan Jindal , Chandana Badrinath , Pranjal Bharti , Lakkidi Vinay , Sachin Dev Sharma

We investigate the effectiveness of fine-tuning large language models (LLMs) on small medical datasets for text classification and named entity recognition tasks. Using a German cardiology report dataset and the i2b2 Smoking Challenge…

Computation and Language · Computer Science 2025-03-28 Noah Losch , Lucas Plagwitz , Antonius Büscher , Julian Varghese

We propose a novel task-agnostic in-domain pre-training method that sits between generic pre-training and fine-tuning. Our approach selectively masks in-domain keywords, i.e., words that provide a compact representation of the target…

Computation and Language · Computer Science 2023-07-17 Shahriar Golchin , Mihai Surdeanu , Nazgol Tavabi , Ata Kiapour

Large Language Models (LLMs) exhibit emerging in-context learning abilities through prompt engineering. The recent progress in large-scale generative models has further expanded their use in real-world language applications. However, the…

Computation and Language · Computer Science 2024-04-12 Linyi Yang , Shuibai Zhang , Zhuohao Yu , Guangsheng Bao , Yidong Wang , Jindong Wang , Ruochen Xu , Wei Ye , Xing Xie , Weizhu Chen , Yue Zhang

In recent years, major advancements in natural language processing (NLP) have been driven by the emergence of large language models (LLMs), which have significantly revolutionized research and development within the field. Building upon…

Computation and Language · Computer Science 2023-05-09 Hazal Türkmen , Oğuz Dikenelli , Cenk Eraslan , Mehmet Cem Çallı , Süha Süreyya Özbek

Language models (LMs) have been instrumental for the rapid advance of natural language processing. This paper studies continual pre-training of LMs, in particular, continual domain-adaptive pre-training (or continual DAP-training). Existing…

Computation and Language · Computer Science 2023-04-13 Zixuan Ke , Yijia Shao , Haowei Lin , Tatsuya Konishi , Gyuhak Kim , Bing Liu