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Histopathological tissue classification is a fundamental task in pathomics cancer research. Precisely differentiating different tissue types is a benefit for the downstream researches, like cancer diagnosis, prognosis and etc. Existing…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Jiatai Lin , Guoqiang Han , Xipeng Pan , Hao Chen , Danyi Li , Xiping Jia , Zhenwei Shi , Zhizhen Wang , Yanfen Cui , Haiming Li , Changhong Liang , Li Liang , Zaiyi Liu , Chu Han

Breast cancer is the most diagnosed cancer and the most predominant cause of death in women worldwide. Imaging techniques such as the breast cancer pathology helps in the diagnosis and monitoring of the disease. However identification of…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Francisco Perdigon Romero , An Tang , Samuel Kadoury

Histopathological characterization of colorectal polyps allows to tailor patients' management and follow up with the ultimate aim of avoiding or promptly detecting an invasive carcinoma. Colorectal polyps characterization relies on the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Carlo Alberto Barbano , Daniele Perlo , Enzo Tartaglione , Attilio Fiandrotti , Luca Bertero , Paola Cassoni , Marco Grangetto

Histopathological image classification constitutes a pivotal task in computer-aided diagnostics. The precise identification and categorization of histopathological images are of paramount significance for early disease detection and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Weiping Ding , Tianyi Zhou , Jiashuang Huang , Shu Jiang , Tao Hou , Chin-Teng Lin

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Recent developments in deep learning have made remarkable progress in speeding up the prediction of quantum chemical (QC) properties by removing the need for expensive electronic structure calculations like density functional theory.…

Chemical Physics · Physics 2023-07-10 Shuqi Lu , Zhifeng Gao , Di He , Linfeng Zhang , Guolin Ke

Histopathology nuclei segmentation is crucial for quantitative tissue analysis and cancer diagnosis. Although existing segmentation methods have achieved strong performance, they are often computationally heavy and show limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Muhammad Hassan Maqsood , Yanming Zhu , Alfred Lam , Getamesay Dagnaw , Xuefei Yin , Alan Wee-Chung Liew

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh

Nucleus detection and classification (NDC) in histopathology analysis is a fundamental task that underpins a wide range of high-level pathology applications. However, existing methods heavily rely on labor-intensive nucleus-level…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Zijiang Yang , Hanqing Chao , Bokai Zhao , Yelin Yang , Yunshuo Zhang , Dongmei Fu , Junping Zhang , Le Lu , Ke Yan , Dakai Jin , Minfeng Xu , Yun Bian , Hui Jiang

Universal segmentation models offer significant potential in addressing a wide range of tasks by effectively leveraging discrete annotations. As the scope of tasks and modalities expands, it becomes increasingly important to generate and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Yiwen Ye , Ziyang Chen , Jianpeng Zhang , Yutong Xie , Yong Xia

Molecular subtyping of breast cancer is crucial for personalized treatment and prognosis. Traditional classification approaches rely on either histopathological images or gene expression profiling, limiting their predictive power. In this…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Amin Honarmandi Shandiz

Histopathology image analysis is critical yet challenged by the demand of segmenting tissue regions and nuclei instances for tumor microenvironment and cellular morphology analysis. Existing studies focused on tissue semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Qing Xu , Wenting Duan , Zhen Chen

Latent diffusion models (LDM) have revolutionized text-to-image generation, leading to the proliferation of various advanced models and diverse downstream applications. However, despite these significant advancements, current diffusion…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Jiacheng Zhang , Jie Wu , Yuxi Ren , Xin Xia , Huafeng Kuang , Pan Xie , Jiashi Li , Xuefeng Xiao , Weilin Huang , Shilei Wen , Lean Fu , Guanbin Li

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

The application of machine learning techniques to the medical domain is especially challenging due to the required level of precision and the incurrence of huge risks of minute errors. Employing these techniques to a more complex subdomain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Ekta Gavas , Kaustubh Olpadkar

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

Medical image segmentation has achieved remarkable advancements using deep neural networks (DNNs). However, DNNs often need big amounts of data and annotations for training, both of which can be difficult and costly to obtain. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2021-10-19 Hengji Cui , Dong Wei , Kai Ma , Shi Gu , Yefeng Zheng

The success of supervised deep learning models in medical image segmentation relies on detailed annotations. However, labor-intensive manual labeling is costly and inefficient, especially in dense object segmentation. To this end, we…

Computer Vision and Pattern Recognition · Computer Science 2022-10-17 Pingyi Chen , Chenglu Zhu , Zhongyi Shui , Jiatong Cai , Sunyi Zheng , Shichuan Zhang , Lin Yang

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…