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PET-CT lesion segmentation is challenging due to noise sensitivity, small and variable lesion morphology, and interference from physiological high-metabolic signals. Current mainstream approaches follow the practice of one network solving…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Xinglong Liang , Jiaju Huang , Luyi Han , Tianyu Zhang , Xin Wang , Yuan Gao , Chunyao Lu , Lishan Cai , Tao Tan , Ritse Mann

Recent advancements in multimodal pre-training models have significantly advanced computational pathology. However, current approaches predominantly rely on visual-language models, which may impose limitations from a molecular perspective…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Minghao Han , Dingkang Yang , Jiabei Cheng , Xukun Zhang , Linhao Qu , Zizhi Chen , Lihua Zhang

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Accurate detection and classification of nuclei in histopathology images are critical for diagnostic and research applications. We present KongNet, a multi-headed deep learning architecture featuring a shared encoder and parallel,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaqi Lv , Esha Sadia Nasir , Kesi Xu , Mostafa Jahanifar , Brinder Singh Chohan , Behnaz Elhaminia , Shan E Ahmed Raza

A fundamental challenge in federated learning lies in mixing heterogeneous datasets and classification tasks while minimizing the high communication cost caused by clients as well as the exchange of weight updates with the server over a…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Atefe Hassani , Islem Rekik

Unsupervised domain adaptation (UDA) methods have been broadly utilized to improve the models' adaptation ability in general computer vision. However, different from the natural images, there exist huge semantic gaps for the nuclei from…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Canran Li , Dongnan Liu , Haoran Li , Zheng Zhang , Guangming Lu , Xiaojun Chang , Weidong Cai

Detection of cell nuclei in microscopic images is a challenging research topic, because of limitations in cellular image quality and diversity of nuclear morphology, i.e. varying nuclei shapes, sizes, and overlaps between multiple cell…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Mohammad Tofighi , Tiantong Guo , Jairam K. P. Vanamala , Vishal Monga

Accurate classification of microscopic blood cells is still a critical task in medical image analysis, where subtle variations and limited data can challenge conventional deep learning models. As such, we investigate in this work the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Guilherme Cruz , Nouhaila Innan , Alberto Marchisio , Gabriel Falcao , Muhammad Shafique

Diagnostic pathology, which is the basis and gold standard of cancer diagnosis, provides essential information on the prognosis of the disease and vital evidence for clinical treatment. Tumor region detection, subtype and grade…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Jialun Wu , Haichuan Zhang , Zeyu Gao , Xinrui Bao , Tieliang Gong , Chunbao Wang , Chen Li

Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Xueyuan Li , Can Cui , Ruining Deng , Yucheng Tang , Quan Liu , Tianyuan Yao , Shunxing Bao , Naweed Chowdhury , Haichun Yang , Yuankai Huo

Pathological cell semantic segmentation is a fundamental technology in computational pathology, essential for applications like cancer diagnosis and effective treatment. Given that multiple cell types exist across various organs, with…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Qing Zhang , Hang Guo , Siyuan Yang , Qingli Li , Yan Wang

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

Neurons and Cognition · Quantitative Biology 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Krithik Ramesh , Ritvik Koneru

Accurate skin cancer diagnosis is vital for early treatment and improved patient outcomes. Deep learning (DL) models have shown promise in automating skin cancer classification, yet challenges remain due to data scarcity and limited…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Cell identity encompasses various semantic aspects of a cell, including cell type, pathway information, disease information, and more, which are essential for biologists to gain insights into its biological characteristics. Understanding…

Genomics · Quantitative Biology 2024-06-12 Suyuan Zhao , Jiahuan Zhang , Yushuai Wu , Yizhen Luo , Zaiqing Nie

With the growth of deep learning, how to describe deep neural networks unifiedly is becoming an important issue. We first formalize neural networks mathematically with their directed graph representations, and prove a generation theorem…

Machine Learning · Computer Science 2018-05-11 Yujian Li , Chuanhui Shan

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Automated cell nucleus segmentation and classification are required to assist pathologists in their decision making. The Colon Nuclei Identification and Counting Challenge 2022 (CoNIC Challenge 2022) supports the development and…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Moritz Böhland , Oliver Neumann , Marcel P. Schilling , Markus Reischl , Ralf Mikut , Katharina Löffler , Tim Scherr

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Cell detection in histopathology images is of great value in clinical practice. \textit{Convolutional neural networks} (CNNs) have been applied to cell detection to improve the detection accuracy, where cell annotations are required for…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Zipei Zhao , Fengqian Pang , Zhiwen Liu , Chuyang Ye
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