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Healthcare clinics regularly encounter dynamic data that changes due to variations in patient populations, treatment policies, medical devices, and emerging disease patterns. Deep learning models can suffer from catastrophic forgetting when…

Machine Learning · Computer Science 2023-11-09 Amritpal Singh , Mustafa Burak Gurbuz , Shiva Souhith Gantha , Prahlad Jasti

Low grade gliomas (LGGs) are infiltrative and incurable primary brain tumours with typically slow evolution. These tumours usually occur in young and otherwise healthy patients, bringing controversies in treatment planning since aggressive…

Protein mutations can have profound effects on biological function, making accurate prediction of property changes critical for drug discovery, protein engineering, and precision medicine. Current approaches rely on fine-tuning…

Machine Learning · Computer Science 2025-10-27 Srivathsan Badrinarayanan , Yue Su , Janghoon Ock , Alan Pham , Sanya Ahuja , Amir Barati Farimani

Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official WHO classification CNS. These guidelines…

Applications · Statistics 2023-05-23 Roberta Coletti , Mónica L. Mendonça , Susana Vinga , Marta B. Lopes

With the rise in importance of personalized medicine, we trained personalized neural networks to detect tumor progression in longitudinal datasets. The model was evaluated on two datasets with a total of 64 scans from 32 patients diagnosed…

Machine Learning · Computer Science 2022-10-28 Christian Strack , Kelsey L. Pomykala , Heinz-Peter Schlemmer , Jan Egger , Jens Kleesiek

Low grade gliomas (LGGs) are a group of primary brain tumors usually encountered in young patient populations. These tumors represent a difficult challenge because many patients survive a decade or more and may be at a higher risk for…

Deep learning for regression tasks on medical imaging data has shown promising results. However, compared to other approaches, their power is strongly linked to the dataset size. In this study, we evaluate 3D-convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Yannick Suter , Alain Jungo , Michael Rebsamen , Urspeter Knecht , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

Cancer grade is a critical clinical criterion that can be used to determine the degree of cancer malignancy. Revealing the condition of the glands, a precise gland segmentation can assist in a more effective cancer grade classification. In…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Yijie Zhu , Shan E Ahmed Raza

The problem of automatic software generation is known as Machine Programming. In this work, we propose a framework based on genetic algorithms to solve this problem. Although genetic algorithms have been used successfully for many problems,…

Neural and Evolutionary Computing · Computer Science 2023-04-04 Shantanu Mandal , Todd A. Anderson , Javier S. Turek , Justin Gottschlich , Shengtian Zhou , Abdullah Muzahid

Reaction-diffusion models have been proposed for decades to capture the growth of gliomas, the most common primary brain tumours. However, severe limitations regarding the estimation of the initial conditions and parameter values of such…

Manifold learning methods are an invaluable tool in today's world of increasingly huge datasets. Manifold learning algorithms can discover a much lower-dimensional representation (embedding) of a high-dimensional dataset through non-linear…

Machine Learning · Computer Science 2021-08-24 Andrew Lensen , Bing Xue , Mengjie Zhang

Glioblastoma is profoundly heterogeneous in microstructure and vasculature, which may lead to tumor regional diversity and distinct treatment response. Although successful in tumor sub-region segmentation and survival prediction, radiomics…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Yifan Li , Chao Li , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

This study focuses on automatic skin cancer detection using a Meta-learning approach for dermoscopic images. The aim of this study is to explore the benefits of the generalization of the knowledge extracted from non-medical data in the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Sara I. Garcia

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Learning robust 3D shape segmentation functions with deep neural networks has emerged as a powerful paradigm, offering promising performance in producing a consistent part segmentation of each 3D shape. Generalizing across 3D shape…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Yu Hao , Hao Huang , Shuaihang Yuan , Yi Fang

Differentiating the intrinsic subtypes of breast cancer is crucial for deciding the best treatment strategy. Deep learning can predict the subtypes from genetic information more accurately than conventional statistical methods, but to date,…

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ha Anh Vu

Brain is an organ that controls activities of all the parts of the body. Recognition of automated brain tumor in Magnetic resonance imaging (MRI) is a difficult task due to complexity of size and location variability. This automatic method…

Medical Physics · Physics 2017-06-21 Neha Rani , Sharda Vashisth

Integrating experimental data into ecological models plays a central role in understanding biological mechanisms that drive tumor progression where such knowledge can be used to develop new therapeutic strategies. While the current studies…

Biological Physics · Physics 2021-04-21 Youness Azimzade , Abbas Ali Saberi , Robert A. Gatenby

Major efforts to sequence cancer genomes are now occurring throughout the world. Though the emerging data from these studies are illuminating, their reconciliation with epidemiologic and clinical observations poses a major challenge. In the…

Populations and Evolution · Quantitative Biology 2010-11-18 Ivana Bozic , Tibor Antal , Hisashi Ohtsuki , Hannah Carter , Dewey Kim , Sining Chen , Rachel Karchin , Kenneth W. Kinzler , Bert Vogelstein , Martin A. Nowak