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We propose a multi-metric flexible Bayesian framework to support efficient interim decision-making in multi-arm multi-stage phase II clinical trials. Multi-arm multi-stage phase II studies increase the efficiency of drug development, but…
In multiple testing scenarios, typically the sign of a parameter is inferred when its estimate exceeds some significance threshold in absolute value. Typically, the significance threshold is chosen to control the experimentwise type I error…
A/B testing, or online experiment is a standard business strategy to compare a new product with an old one in pharmaceutical, technological, and traditional industries. Major challenges arise in online experiments of two-sided marketplace…
Consider a scenario where a harmfulness evaluation metric intended to filter unsafe responses from a Large Language Model. When applied to individual harmful prompt-response pairs, it correctly flags them as unsafe by assigning a high-risk…
We propose a distributional framework for benchmarking socio-technical risks of foundation models with quantified statistical significance. Our approach hinges on a new statistical relative testing based on first and second order stochastic…
Metrics can be used by businesses to make more objective decisions based on data. Software startups in particular are characterized by the uncertain or even chaotic nature of the contexts in which they operate. Using data in the form of…
User-randomized A/B testing has emerged as the gold standard for online experimentation. However, when this kind of approach is not feasible due to legal, ethical or practical considerations, experimenters have to consider alternatives like…
Quality control is a crucial activity performed by manufacturing enterprises to ensure that their products meet quality standards and avoid potential damage to the brand's reputation. The decreased cost of sensors and connectivity enabled…
Software companies have widely used online A/B testing to evaluate the impact of a new technology by offering it to groups of users and comparing it against the unmodified product. However, running online A/B testing needs not only efforts…
Advanced AI technologies are serving humankind in a number of ways, from healthcare to manufacturing. Advanced automated machines are quite expensive, but the end output is supposed to be of the highest possible quality. Depending on the…
We address the problem of A/B testing, a widely used protocol for evaluating the potential improvement achieved by a new decision system compared to a baseline. This protocol segments the population into two subgroups, each exposed to a…
Applying Artificial Intelligence (AI) and Machine Learning (ML) in critical contexts, such as medicine, requires the implementation of safety measures to reduce risks of harm in case of prediction errors. Spotting ML failures is of…
Empirical research in the social and medical sciences frequently involves testing multiple hypotheses simultaneously, increasing the risk of false positives due to chance. Classical multiple testing procedures, such as the Bonferroni…
The problem of simultaneously testing the marginal distributions of sequentially monitored, independent data streams is considered. The decisions for the various testing problems can be made at different times, using data from all streams,…
In this paper we consider the problem of multiple testing when the hypotheses are dependent. In most of the existing literature, either Bayesian or non-Bayesian, the decision rules mainly focus on the validity of the test procedure rather…
Designing products to meet consumers' preferences is essential for a business's success. We propose the Gradient-based Survey (GBS), a discrete choice experiment for multiattribute product design. The experiment elicits consumer preferences…
Embedded systems interaction with environment inherently complicates understanding of requirements and their correct implementation. However, product uncertainty is highest during early stages of development. Design verification is an…
Recommender systems have become an integral part of online platforms, providing personalized recommendations for purchases, content consumption, and interpersonal connections. These systems consist of two sides: the producer side comprises…
When developing a new networking algorithm, it is established practice to run a randomized experiment, or A/B test, to evaluate its performance. In an A/B test, traffic is randomly allocated between a treatment group, which uses the new…
Technical and legal debates frequently suggest that "accuracy" is an objective, measurable, and purely technical property. We challenge this view, showing that evaluating AI performance fundamentally depends on context-dependent normative…