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Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Objective: The clinical diagnosis of developmental dysplasia of the hip (DDH) typically involves manually measuring key radiological angles -- Center-Edge (CE), Tonnis, and Sharp angles -- from pelvic radiographs, a process that is…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Yang Li , Leo Yan Li-Han , Hua Tian

While recent advances in deep learning have significantly advanced the state of the art for vessel detection in color fundus (CF) images, the success for detecting vessels in fluorescein angiography (FA) has been stymied due to the lack of…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Li Ding , Mohammad H. Bawany , Ajay E. Kuriyan , Rajeev S. Ramchandran , Charles C. Wykoff , Gaurav Sharma

Volatile organic compounds (VOCs) are valuable health indicators, with synthetic breath biomarkers offering rapid and disease specific diagnostics. However, their <100 ppb level exhalation requires mass spectrometry, limiting clinical…

Coronary heart disease is a common cause of death despite being preventable. To treat the underlying plaque deposits in the arterial walls, intravascular optical coherence tomography can be used by experts to detect and characterize the…

Computer Vision and Pattern Recognition · Computer Science 2018-08-27 Nils Gessert , Matthias Lutz , Markus Heyder , Sarah Latus , David M. Leistner , Youssef S. Abdelwahed , Alexander Schlaefer

Purpose: Automatic methods are required for the early detection of hepatic steatosis to avoid progression to cirrhosis and cancer. Here, we developed a fully automated deep learning pipeline to quantify hepatic steatosis on non-contrast…

Quantitative Methods · Quantitative Biology 2022-02-08 Zhongyi Zhang , Jakob Weiss , Jana Taron , Roman Zeleznik , Michael T. Lu , Hugo J. W. L. Aerts

Combining high-throughput experiments with machine learning allows quick optimization of parameter spaces towards achieving target properties. In this study, we demonstrate that machine learning, combined with multi-labeled datasets, can…

Measuring NT-proBNP biomarker is recommended for preliminary diagnostics of the heart failure. Recent studies suggest a possibility of early screening of biomarkers in saliva for non-invasive identification of cardiac diseases at the…

Cardiovascular diseases (CVDs) are responsible for a large proportion of premature deaths in low- and middle-income countries. Early CVD detection and intervention is critical in these populations, yet many existing CVD risk scores require…

Vector network analyzers (VNAs) have become one of the indispensable tools in various fields, such as medicine, material, geology, communication, and etc, due to the capacity of measuring and analyzing the response of the object under test.…

Signal Processing · Electrical Eng. & Systems 2020-02-18 Zhengtao Jin , Guiling Wu , Min Ding , Jianping Chen

Visual field tests (VFT) are pivotal for glaucoma diagnosis and conducted regularly to monitor disease progression. Here we address the question to what degree aggregate VFT measurements such as Visual Field Index (VFI) and Mean Deviation…

Computer Vision and Pattern Recognition · Computer Science 2019-10-11 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel Schuman , Rahil Garnavi

The precise detection of mild cognitive impairment (MCI) is of significant importance in preventing the deterioration of patients in a timely manner. Although hypergraphs have enhanced performance by learning and analyzing brain networks,…

Machine Learning · Computer Science 2025-01-14 Manman Yuan , Weiming Jia , Xiong Luo , Jiazhen Ye , Peican Zhu , Junlin Li

The coagulation of blood after it is drawn from the body poses a significant challenge for hematological analysis, potentially leading to inaccurate test results and altered cellular characteristics, compromising diagnostic reliability.…

Hearth Rate (HR) monitoring is increasingly performed in wrist-worn devices using low-cost photoplethysmography (PPG) sensors. However, Motion Artifacts (MAs) caused by movements of the subject's arm affect the performance of PPG-based HR…

Signal Processing · Electrical Eng. & Systems 2022-03-29 Alessio Burrello , Daniele Jahier Pagliari , Matteo Risso , Simone Benatti , Enrico Macii , Luca Benini , Massimo Poncino

Aggregation-based assays, using micro- and nano-particles have been widely accepted as an efficient and cost-effective bio-sensing tool, particularly in microbiology, where particle clustering events are used as a metric to infer the…

Instrumentation and Detectors · Physics 2018-12-31 Yichen Wu , Aniruddha Ray , Qingshan Wei , Alborz Feizi , Xin Tong , Eva Chen , Yi Luo , Aydogan Ozcan

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Deep learning-based optical flow (DLOF) extracts features in adjacent video frames with deep convolutional neural networks. It uses those features to estimate the inter-frame motions of objects at the pixel level. In this article, we…

Synthetic Aperture Vector Flow Imaging (SA-VFI) can visualize complex cardiac and vascular blood flow patterns at high temporal resolution with a large field of view. Convolutional neural networks (CNNs) are commonly used in image and video…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Thomas Robins , Antonio Stanziola , Kai Reimer , Peter Weinberg , Meng-Xing Tang

Deep convolutional neural networks (DCNNs) are a class of artificial neural networks, primarily for computer vision tasks such as segmentation and classification. Many nonlinear operations, such as activation functions and pooling…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zuocheng Wen , Lingzhong Guo

Vision transformers (ViTs) have been trending in image classification tasks due to their promising performance when compared to convolutional neural networks (CNNs). As a result, many researchers have tried to incorporate ViTs in…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Swalpa Kumar Roy , Ankur Deria , Danfeng Hong , Behnood Rasti , Antonio Plaza , Jocelyn Chanussot