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Large Language Models (LLMs) are advanced Artificial Intelligence (AI) systems that have undergone extensive training using large datasets in order to understand and produce language that closely resembles that of humans. These models have…

Software Engineering · Computer Science 2023-08-10 Alessio Buscemi

Protein language models (pLMs) have emerged as powerful predictors of protein structure and function. However, the computational circuits underlying their predictions remain poorly understood. Recent mechanistic interpretability methods…

Machine Learning · Computer Science 2026-05-14 Darin Tsui , Kunal Talreja , Daniel Saeedi , Amirali Aghazadeh

Recent developments in Large Language Models (LLMs) have demonstrated their remarkable capabilities across a range of tasks. Questions, however, persist about the nature of LLMs and their potential to integrate common-sense human knowledge…

Artificial Intelligence · Computer Science 2024-06-13 Huatao Xu , Liying Han , Qirui Yang , Mo Li , Mani Srivastava

Artificial Intelligence and especially Large Language Models (LLM), such as ChatGPT has revolutionized the way educators work. The results we get from LLMs depend on how we ask them to help us. The process and the technique behind an…

Physics Education · Physics 2025-10-13 Dimitrios Gousopoulos

Protein language models have shown remarkable success in learning biological information from protein sequences. However, most existing models are limited by either autoencoding or autoregressive pre-training objectives, which makes them…

Quantitative Methods · Quantitative Biology 2024-12-10 Bo Chen , Xingyi Cheng , Pan Li , Yangli-ao Geng , Jing Gong , Shen Li , Zhilei Bei , Xu Tan , Boyan Wang , Xin Zeng , Chiming Liu , Aohan Zeng , Yuxiao Dong , Jie Tang , Le Song

With ChatGPT under the spotlight, utilizing large language models (LLMs) to assist academic writing has drawn a significant amount of debate in the community. In this paper, we aim to present a comprehensive study of the detectability of…

Computation and Language · Computer Science 2024-03-19 Zeyan Liu , Zijun Yao , Fengjun Li , Bo Luo

Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…

Genomics · Quantitative Biology 2024-09-24 Gonzalo Benegas , Chengzhong Ye , Carlos Albors , Jianan Canal Li , Yun S. Song

Large language models (LLMs), such as ChatGPT, have demonstrated impressive performance in the text generation task, showing the ability to understand and respond to complex instructions. However, the performance of naive LLMs in speciffc…

Computation and Language · Computer Science 2025-12-12 HuangChao Xu , Baohua Zhang , Zhong Jin , Tiannian Zhu , Quansheng Wu , Hongming Weng

Large Language Models (LLMs) are frequently discussed in academia and the general public as support tools for virtually any use case that relies on the production of text, including software engineering. Currently there is much debate, but…

Software Engineering · Computer Science 2024-05-22 Ranim Khojah , Mazen Mohamad , Philipp Leitner , Francisco Gomes de Oliveira Neto

Large Language Models (LLMs) are increasingly applied in the fields of mechanical engineering and materials science. As models that establish connections through the interface of language, LLMs can be applied for step-wise reasoning through…

Applied Physics · Physics 2025-07-22 Adrian Ehrenhofer , Thomas Wallmersperger , Gianaurelio Cuniberti

The field of data visualisation has long aimed to devise solutions for generating visualisations directly from natural language text. Research in Natural Language Interfaces (NLIs) has contributed towards the development of such techniques.…

Human-Computer Interaction · Computer Science 2023-02-14 Paula Maddigan , Teo Susnjak

Large language models (LLMs) can be used as accessible and intelligent chatbots by constructing natural language queries and directly inputting the prompt into the large language model. However, different prompt' constructions often lead to…

Computation and Language · Computer Science 2023-12-14 Jinta Weng , Jiarui Zhang , Yue Hu , Daidong Fa , Xiaofeng Xuand , Heyan Huang

Large language models (LLMs) like ChatGPT have shown significant advancements across diverse natural language understanding (NLU) tasks, including intelligent dialogue and autonomous agents. Yet, lacking widely acknowledged testing…

Computation and Language · Computer Science 2024-05-10 Jinyang Wu , Feihu Che , Xinxin Zheng , Shuai Zhang , Ruihan Jin , Shuai Nie , Pengpeng Shao , Jianhua Tao

Protein language models (pLMs) have recently gained significant attention for their ability to uncover relationships between sequence, structure, and function from evolutionary statistics, thereby accelerating therapeutic drug discovery.…

Machine Learning · Computer Science 2026-03-04 Darshan Patil , Pranshu Malviya , Mathieu Reymond , Quentin Fournier , Sarath Chandar

Large language models (LLMs) such as ChatGPT can produce coherent, cohesive, relevant, and fluent answers for various natural language processing (NLP) tasks. Taking document-level machine translation (MT) as a testbed, this paper provides…

Computation and Language · Computer Science 2023-10-25 Longyue Wang , Chenyang Lyu , Tianbo Ji , Zhirui Zhang , Dian Yu , Shuming Shi , Zhaopeng Tu

Apart from what (little) OpenAI may be concealing from us, we all know (roughly) how ChatGPT works (its huge text database, its statistics, its vector representations, and their huge number of parameters, its next-word training, and so on).…

Computation and Language · Computer Science 2025-02-18 Stevan Harnad

Large Language Models (LLMs) represent a class of deep learning models adept at understanding natural language and generating coherent responses to various prompts or queries. These models far exceed the complexity of conventional neural…

Machine Learning · Computer Science 2024-12-05 Minghao Shao , Abdul Basit , Ramesh Karri , Muhammad Shafique

Humankind's understanding of the world is fundamentally linked to our perception and cognition, with \emph{human languages} serving as one of the major carriers of \emph{world knowledge}. In this vein, \emph{Large Language Models} (LLMs)…

Artificial Intelligence · Computer Science 2024-06-27 Huajun Chen

Coverage of ChatGPT-style large language models (LLMs) in the media has focused on their eye-catching achievements, including solving advanced mathematical problems and reaching expert proficiency in medical examinations. But the gradual…

Computers and Society · Computer Science 2024-03-26 Djavan De Clercq , Elias Nehring , Harry Mayne , Adam Mahdi

Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…

Biomolecules · Quantitative Biology 2025-09-15 Long-Kai Huang , Rongyi Zhu , Bing He , Jianhua Yao
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