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Hyperparameter tuning in machine learning algorithms is a computationally challenging task due to the large-scale nature of the problem. In order to develop an efficient strategy for hyper-parameter tuning, one promising solution is to use…

Neural and Evolutionary Computing · Computer Science 2021-12-17 Leila Zahedi , Farid Ghareh Mohammadi , M. Hadi Amini

Optimal selection of interdependent IT Projects for implementation in multi periods has been challenging in the framework of real option valuation. This paper presents a mathematical optimization model for multi-stage portfolio of IT…

Computational Engineering, Finance, and Science · Computer Science 2010-06-15 Shashank Pushkar , Abhijit Mustafi , Akhileshwar Mishra

Proton pencil beam scanning (PBS) treatment planning for head and neck (H&N) cancers is a time-consuming and experience-demanding task where a large number of planning objectives are involved. Deep reinforcement learning (DRL) has recently…

Quantitative Methods · Quantitative Biology 2024-09-19 Qingqing Wang , Chang Chang

Optimal resource allocation is gaining a renewed interest due its relevance as a core problem in managing, over time, cloud and high-performance computing facilities. Semi-Bandit Feedback (SBF) is the reference method for efficiently…

Machine Learning · Computer Science 2022-10-13 Antonio Candelieri , Andrea Ponti , Francesco Archetti

Multivariate meta-analysis (MMA) is a powerful tool for jointly estimating multiple outcomes' treatment effects. However, the validity of results from MMA is potentially compromised by outcome reporting bias (ORB), or the tendency for…

Applications · Statistics 2021-10-19 Ray Bai , Xiaokang Liu , Lifeng Lin , Yulun Liu , Stephen E. Kimmel , Haitao Chu , Yong Chen

To move through the world, mobile robots typically use a receding-horizon strategy, wherein they execute an old plan while computing a new plan to incorporate new sensor information. A plan should be dynamically feasible, meaning it obeys…

Optimization and Control · Mathematics 2020-03-05 Shreyas Kousik , Bohao Zhang , Pengcheng Zhao , Ram Vasudevan

In intensity-modulated radiation therapy, optimal intensity distributions of incoming beams are decomposed into linear combinations of leaf openings of a multileaf collimator (segments). In order to avoid inefficient dose delivery, the…

Medical Physics · Physics 2010-09-29 Antje Kiesel , Tobias Gauer

Radiation response in cancer is shaped by complex, patient specific biology, yet current treatment strategies often rely on uniform dose prescriptions without accounting for tumor heterogeneity. In this study, we introduce a meta learning…

Medical Physics · Physics 2025-08-12 Hao Peng , Yuanyuan Zhang , Steve Jiang , Robert Timmerman , John Minna

Solving an optimization task in any domain is a very challenging problem, especially when dealing with nonlinear problems and non-convex functions. Many meta-heuristic algorithms are very efficient when solving nonlinear functions. A…

Neural and Evolutionary Computing · Computer Science 2020-07-28 Mona Nasr , Omar Farouk , Ahmed Mohamedeen , Ali Elrafie , Marwan Bedeir , Ali Khaled

This paper reviews recent advances in big data optimization, providing the state-of-art of this emerging field. The main focus in this review are optimization techniques being applied in big data analysis environments. Integer linear…

Neural and Evolutionary Computing · Computer Science 2021-02-04 Ricardo Di Pasquale , Javier Marenco

Cancer is a heterogeneous disease and tumours of the same type can differ greatly at the genetic and phenotypic levels. Understanding how these differences impact sensitivity to treatment is an essential step towards patient-specific…

Tissues and Organs · Quantitative Biology 2023-02-28 Chloé Colson , Philip K. Maini , Helen M. Byrne

Nowadays, we are immersed in tens of newly-proposed evolutionary and swam-intelligence metaheuristics, which makes it very difficult to choose a proper one to be applied on a specific optimization problem at hand. On the other hand, most of…

Neural and Evolutionary Computing · Computer Science 2020-01-27 Hamid Reza Boveiri , Raouf Khayami

Neural networks have been proposed for medical image registration by learning, with a substantial amount of training data, the optimal transformations between image pairs. These trained networks can further be optimized on a single pair of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Zachary MC Baum , Yipeng Hu , Dean C Barratt

Thanks to advancements in diagnosis and treatment, prostate cancer patients have high long-term survival rates. Currently, an important goal is to preserve quality-of-life during and after treatment. The relationship between the radiation a…

Quantitative Methods · Quantitative Biology 2026-05-12 Zhijian Yang , Daniel Olszewski , Chujun He , Giulia Pintea , Jun Lian , Tom Chou , Ronald Chen , Blerta Shtylla

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated…

Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning…

Medical Physics · Physics 2022-06-13 Aly Khalifa , Jeff Winter , Inmaculada Navarro , Chris McIntosh , Thomas G. Purdie

Metaheuristic algorithms are optimization methods that are inspired by real phenomena in nature or the behavior of living beings, e.g., animals, to be used for solving complex problems, as in engineering, energy optimization, health care,…

Neural and Evolutionary Computing · Computer Science 2025-06-16 Ardalan H. Awlla , Tarik A. Rashid , Ronak M. Abdullah

Bat Algorithm (BA) is a nature-inspired metaheuristic search algorithm designed to efficiently explore complex problem spaces and find near-optimal solutions. The algorithm is inspired by the echolocation behavior of bats, which acts as a…

Neural and Evolutionary Computing · Computer Science 2024-07-23 Shahla U. Umar , Tarik A. Rashid , Aram M. Ahmed , Bryar A. Hassan , Mohammed Rashad Baker

The aim is to evaluate whether smart worklist prioritization by artificial intelligence (AI) can optimize the radiology workflow and reduce report turnaround times (RTAT) for critical findings in chest radiographs (CXRs). Furthermore, we…