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Physical annealing systems provide heuristic approaches to solving NP-hard Ising optimization problems. Here, we study the performance of two types of annealing machines--a commercially available quantum annealer built by D-Wave Systems,…

We experimentally demonstrate that the bias-field digitized counterdiabatic quantum optimization (BF-DCQO) algorithm, implemented on IonQ's fully connected trapped-ion quantum processors, offers an efficient approach to solving dense…

We report on a case study in programming an early quantum annealer to attack optimization problems related to operational planning. While a number of studies have looked at the performance of quantum annealers on problems native to their…

There has been considerable progress in the design and construction of quantum annealing devices. However, a conclusive detection of quantum speedup over traditional silicon-based machines remains elusive, despite multiple careful studies.…

Quantum Physics · Physics 2015-09-03 Helmut G. Katzgraber , Firas Hamze , Zheng Zhu , Andrew J. Ochoa , H. Munoz-Bauza

The application in cryptography of quantum algorithms for prime factorization fostered the interest in quantum computing. However, quantum computers, and particularly quantum annealers, can also be helpful to construct secure cryptographic…

Quantum Physics · Physics 2021-01-27 Feng Hu , Lucas Lamata , Chao Wang , Xi Chen , Enrique Solano , Mikel Sanz

Molecular docking is a crucial phase in drug discovery, involving the precise determination of the optimal spatial arrangement between two molecules when they bind. The such analysis, the 3D structure of molecules is a fundamental…

Quantum Physics · Physics 2024-03-04 Arit Kumar Bishwas , Arish Pitchai , Anuraj Som

Quantum annealing aims to solve combinatorial optimization problems mapped on to Ising interactions between quantum spins. A critical factor that limits the success of a quantum annealer is its sensitivity to noise, and intensive research…

Quantum Physics · Physics 2019-01-29 Shruti Puri , Christian Kraglund Andersen , Arne L. Grimsmo , Alexandre Blais

We evaluate using programmable superconducting flux qubit D-Wave quantum annealers to approximate the partition function of Ising models. We propose the use of two distinct quantum annealer sampling methods: chains of Monte Carlo-like…

Quantum Physics · Physics 2025-12-23 Thinh Le , Elijah Pelofske

Finding a Hadamard matrix (H-matrix) among the set of all binary matrices of corresponding order is a hard problem, which potentially can be solved by quantum computing. We propose a method to formulate the Hamiltonian of finding H-matrix…

Quantum Physics · Physics 2019-03-27 Andriyan Bayu Suksmono , Yuichiro Minato

The possibility of using quantum computers for electronic structure calculations has opened up a promising avenue for computational chemistry. Towards this direction, numerous algorithmic advances have been made in the last five years. The…

Feature selection is a common step in many ranking, classification, or prediction tasks and serves many purposes. By removing redundant or noisy features, the accuracy of ranking or classification can be improved and the computational cost…

Information Retrieval · Computer Science 2022-05-10 Maurizio Ferrari Dacrema , Fabio Moroni , Riccardo Nembrini , Nicola Ferro , Guglielmo Faggioli , Paolo Cremonesi

A protein is a linear chain containing a set of amino acids, which folds on itself to create a specific native structure, also called the minimum energy conformation. It is the native structure that determines the functionality of each…

Biomolecules · Quantitative Biology 2021-05-28 Nabil Boumedine , Sadek Bouroubi

We benchmark current annealing-based optimization workflows on a greenhouse-inspired quadratic unconstrained binary optimization problem for binary heater scheduling, where the horizon H denotes the number of hourly control decisions. For…

Quantum Physics · Physics 2026-05-28 Hamzeh Alavirad , Maryam Bahrami Zanjani

Quantum(-inspired) annealers show promise in solving combinatorial optimisation problems in practice. There has been extensive researches demonstrating the utility of D-Wave quantum annealer and quantum-inspired annealer, i.e., Fujitsu…

Quantum Physics · Physics 2022-09-27 Tian Huang , Jun Xu , Tao Luo , Xiaozhe Gu , Rick Goh , Weng-Fai Wong

Leveraging the current generation of quantum devices to solve optimization problems of practical interest necessitates the development of hybrid quantum-classical (HQC) solution approaches. In this paper, a multi-cut Benders decomposition…

Quantum Physics · Physics 2023-02-14 Nikolaos G. Paterakis

This work is a benchmark study for quantum-classical computing method with a real-world optimization problem from industry. The problem involves scheduling and balancing jobs on different machines, with a non-linear objective function. We…

Quantum Physics · Physics 2024-08-06 Abhishek Awasthi , Nico Kraus , Florian Krellner , David Zambrano

Quantum annealing aims at finding optimal solutions to complex optimization problems using a suitable quantum many body Hamiltonian encoding the solution in its ground state. To find the solution one typically evolves the ground state of a…

Quantum Physics · Physics 2022-05-13 Elias Starchl , Helmut Ritsch

Recent advances bring within reach the viability of solving combinatorial problems using a quantum annealing algorithm implemented on a purpose-built platform that exploits quantum properties. However, the question of how to tune the…

Data Structures and Algorithms · Computer Science 2014-10-21 Andrew D. King , Catherine C. McGeoch

Here we consider using quantum annealing to solve Set Cover with Pairs (SCP), an NP-hard combinatorial optimization problem that play an important role in networking, computational biology, and biochemistry. We show an explicit construction…

Quantum Physics · Physics 2016-08-31 Yudong Cao , Shuxian Jiang , Debbie Perouli , Sabre Kais

Although quantum computing hardware has evolved significantly in recent years, spurred by increasing industrial and government interest, the size limitation of current generation quantum computers remains an obstacle when applying these…

Quantum Physics · Physics 2020-01-20 Gideon Bass , Max Henderson , Joshua Heath , Joseph Dulny