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In recent years, quantum annealing has gained the status of being a promising candidate for solving various optimization problems. Using a set of hard 2-satisfiabilty (2-SAT) problems, consisting of upto 18-variables problems, we analyze…

Quantum Physics · Physics 2022-06-09 Vrinda Mehta , Fengping Jin , Hans De Raedt , Kristel Michielsen

We investigate a hybrid quantum-classical solution method to the mean-variance portfolio optimization problems. Starting from real financial data statistics and following the principles of the Modern Portfolio Theory, we generate…

Quantum Physics · Physics 2019-07-01 Davide Venturelli , Alexei Kondratyev

Recent advances in quantum technology have led to the development and manufacturing of experimental programmable quantum annealing optimizers that contain hundreds of quantum bits. These optimizers, named `D-Wave' chips, promise to solve…

Quantum Physics · Physics 2015-10-23 Victor Martin-Mayor , Itay Hen

In this report, we explore the use of a quantum optimization algorithm for obtaining low energy conformations of protein models. We discuss mappings between protein models and optimization variables, which are in turn mapped to a system of…

The observation of an unequivocal quantum speedup remains an elusive objective for quantum computing. The D-Wave quantum annealing processors have been at the forefront of experimental attempts to address this goal, given their relatively…

Quantum Physics · Physics 2018-08-08 Tameem Albash , Daniel A. Lidar

Quantum annealing devices such as the ones produced by D-Wave systems are typically used for solving optimization and sampling tasks, and in both academia and industry the characterization of their usefulness is subject to active research.…

Quantum annealing and D-Wave quantum annealer attracted considerable attention for their ability to solve combinatorial optimization problems. In order to solve other type of optimization problems, it is necessary to apply certain kinds of…

Quantum Physics · Physics 2021-05-31 Michiya Kuramata , Ryota Katsuki , Kazuhide Nakata

Quantum annealing was originally proposed as an approach for solving combinatorial optimisation problems using quantum effects. D-Wave Systems has released a production model of quantum annealing hardware. However, the inherent noise and…

Disordered Systems and Neural Networks · Physics 2021-03-16 Takehito Sato , Masayuki Ohzeki , Kazuyuki Tanaka

Ab initio wavefunction methods provide accurate molecular simulations but their computational scaling restricts applications to small systems. We develop a workflow combining quantum embedding to decompose a molecule into fragments with a…

In silico de novo design can drastically cut the costs and time of drug development. In particular, a key advantage of bottom-up physics-based approaches is their independence from training datasets, unlike generative models. However, they…

Quantum Physics · Physics 2025-12-01 Lars Meuser , Alexandros Patsilinakos , Pietro Faccioli

It is the first step for understanding how RNA structure folds from base sequences that to know how its secondary structure is formed. Traditional energy-based algorithms are short of precision, particularly for non-nested sequences, while…

Quantum Physics · Physics 2023-05-18 Ji Jiang , Qipeng Yan , Ye Li , Min Lu , Ziwei Cui , Menghan Dou , Qingchun Wang , Yu-Chun Wu , Guo-Ping Guo

Optimizing the training of a machine learning pipeline helps in reducing training costs and improving model performance. One such optimizing strategy is quantum annealing, which is an emerging computing paradigm that has shown potential in…

Quantum Physics · Physics 2021-06-08 Rajdeep Kumar Nath , Himanshu Thapliyal , Travis S. Humble

Over the past decade, the usefulness of quantum annealing hardware for combinatorial optimization has been the subject of much debate. Thus far, experimental benchmarking studies have indicated that quantum annealing hardware does not…

Optimization and Control · Mathematics 2022-10-11 Byron Tasseff , Tameem Albash , Zachary Morrell , Marc Vuffray , Andrey Y. Lokhov , Sidhant Misra , Carleton Coffrin

Quantum annealing is a promising paradigm for building practical quantum computers. Compared to other approaches, quantum annealing technology has been scaled up to a larger number of qubits. On the other hand, deep learning has been…

Quantum Physics · Physics 2021-07-07 Michele Sasdelli , Tat-Jun Chin

Despite being considered as the next frontier in computation, Quantum Computing is still in an early stage of development. Indeed, current commercial quantum computers suffer from some critical restraints, such as noisy processes and a…

Quantum Physics · Physics 2022-07-04 Esther Villar-Rodriguez , Eneko Osaba , Izaskun Oregi

Cybersecurity in telecommunication networks often leads to hard combinatorial optimization problems that are challenging to solve with classical methods. This work investigates the practical feasibility of using quantum annealing to address…

Quantum Physics · Physics 2026-01-05 Ali Abbassi , Yann Dujardin , Eric Gourdin , Philippe Lacomme , Caroline Prodhon

Quantum annealers of D-Wave Systems, Inc., offer an efficient way to compute high quality solutions of NP-hard problems. This is done by mapping a problem onto the physical qubits of the quantum chip, from which a solution is obtained after…

Quantum Physics · Physics 2022-11-30 Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

We demonstrate that the performance of a quantum annealer on hard random Ising optimization problems can be substantially improved using quantum annealing correction (QAC). Our error correction strategy is tailored to the D-Wave Two device.…

Quantum Physics · Physics 2015-04-03 Kristen L. Pudenz , Tameem Albash , Daniel A. Lidar

Mixed-integer linear programming problems are extensively used in industry for a wide range of optimization tasks. However, as they get larger, they present computational challenges for classical solvers within practical time limits.…

Quantum Physics · Physics 2026-01-21 Sergio López-Baños , Elisabeth Lobe , Ontje Lünsdorf , Oriol Raventós

Lattice QCD in the strong coupling regime can be formulated in dual variables which are integer-valued. It can be efficiently simulated for modest finite temperatures and finite densities via the worm algorithm, circumventing the finite…

High Energy Physics - Lattice · Physics 2023-07-18 Jangho Kim , Thomas Luu , Wolfgang Unger