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In the pursuit of achieving near-term quantum advantage for combinatorial optimization problems, the Quantum Approximate Optimization Algorithm (QAOA) and the Variational Quantum Eigensolver (VQE) are the primary methods of interest, but…

Quantum Physics · Physics 2025-03-06 Adelina Bärligea , Benedikt Poggel , Jeanette Miriam Lorenz

Distributed Quantum Computing (DQC) enables scalability by interconnecting multiple QPUs. Among various DQC implementations, quantum data centers (QDCs), which utilize reconfigurable optical switch networks to link QPUs across different…

The Quadratic Unconstrained Binary Optimization (QUBO) model has gained prominence in recent years with the discovery that it unifies a rich variety of combinatorial optimization problems. By its association with the Ising problem in…

Data Structures and Algorithms · Computer Science 2019-11-06 Fred Glover , Gary Kochenberger , Yu Du

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

A black-box optimization algorithm such as Bayesian optimization finds extremum of an unknown function by alternating inference of the underlying function and optimization of an acquisition function. In a high-dimensional space, such…

Quantum Physics · Physics 2021-05-03 Syun Izawa , Koki Kitai , Shu Tanaka , Ryo Tamura , Koji Tsuda

Quantum annealers offer an efficient way to compute high quality solutions of NP-hard problems when expressed in a QUBO (quadratic unconstrained binary optimization) or an Ising form. This is done by mapping a problem onto the physical…

Quantum Physics · Physics 2022-04-26 Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

Quadratic unconstrained binary optimization (QUBO) is the standard interface to quantum annealers, yet a single constrained task admits many QUBO encodings whose penalty choices reshape the energy landscape experienced by hardware. We study…

Advancements in quantum computing are fuelling emerging applications across disciplines, including finance, where quantum and quantum-inspired algorithms can now make market predictions, detect fraud, and optimize portfolios. Expanding this…

Quantum Physics · Physics 2023-01-06 Anna G. Hughes , Jack S. Baker , Santosh Kumar Radha

Quantum annealers, such as the device built by D-Wave Systems, Inc., offer a way to compute solutions of NP-hard problems that can be expressed in Ising or QUBO (quadratic unconstrained binary optimization) form. Although such solutions are…

Quantum Physics · Physics 2022-10-27 Aaron Barbosa , Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

Routing in wireless communication networks is shaped by mobility, interference, congestion, and competing service requirements, making route selection a high-dimensional constrained optimization problem rather than a simple shortest-path…

Satellite image acquisition scheduling is a problem that is omnipresent in the earth observation field; its goal is to find the optimal subset of images to be taken during a given orbit pass under a set of constraints. This problem, which…

This study further explores reformulating power flow (PF) analysis as a discrete combinatorial optimization problem, proposed in our earlier study using the Adiabatic Quantum Power Flow (AQPF) algorithm, which can be executed on Ising…

Systems and Control · Electrical Eng. & Systems 2026-03-10 Zeynab Kaseb , Matthias Moller , Pedro P. Vergara , Peter Palensky

Quantum annealing has emerged as a powerful tool for solving combinatorial optimization problems efficiently, making use of the principles of quantum mechanics. Companies are increasingly investing in the market of quantum computers,…

Quantum Physics · Physics 2025-09-29 Lorenzo Mazzei , Giada Beccari , Mirko Laruina , Marco Cococcioni

Recent advances in the development of commercial quantum annealers such as the D-Wave 2X allow solving NP-hard optimization problems that can be expressed as quadratic unconstrained binary programs. However, the relatively small number of…

Quantum Physics · Physics 2018-02-01 Georg Hahn , Hristo N. Djidjev

Quantum annealing is a novel type of analog computation that aims to use quantum mechanical fluctuations to search for optimal solutions of Ising problems. Quantum annealing in the Transverse Ising model, implemented on D-Wave QPUs, are…

Quantum Physics · Physics 2025-03-14 Elijah Pelofske

The field of Quantum Computing has gathered significant popularity in recent years and a large number of papers have studied its effectiveness in tackling many tasks. We focus in particular on Quantum Annealing (QA), a meta-heuristic solver…

Quantum Physics · Physics 2026-03-03 Riccardo Pellini , Maurizio Ferrari Dacrema

Recent studies on quantum computing algorithms focus on excavating features of quantum computers which have potential for contributing to computational model enhancements. Among various approaches, quantum annealing methods effectively…

Quantum Physics · Physics 2021-11-02 Sun Woo Park , Hyunju Lee , Byung Chun Kim , Youngho Woo , Kyungtaek Jun

Graph partitioning has many applications in powersystems from decentralized state estimation to parallel simulation. Focusing on parallel simulation, optimal grid partitioning minimizes the idle time caused by different simulation times for…

Systems and Control · Electrical Eng. & Systems 2025-07-14 Carsten Hartmann , Junjie Zhang , Carlos D. Gonzalez Calaza , Thiemo Pesch , Kristel Michielsen , Andrea Benigni

We present a method to formulate the unit commitment problem in energy production as quadratic unconstrained binary optimization (QUBO) problem, which can be solved by classical algorithms and quantum computers. We suggest a first approach…

Quantum Physics · Physics 2023-01-04 M. C. Braun , T. Decker , N. Hegemann , S. F. Kerstan , F. Lorenz

The advent of quantum computing processors with possibility to scale beyond experimental capacities magnifies the importance of studying their applications. Combinatorial optimization problems can be one of the promising applications of…

Quantum Physics · Physics 2017-08-18 Ehsan Zahedinejad , Arman Zaribafiyan
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