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The scarcity of high-quality multimodal biomedical data limits the ability to effectively fine-tune pretrained Large Language Models (LLMs) for specialized biomedical tasks. To address this challenge, we introduce MINT (Multimodal…

Quantitative Methods · Quantitative Biology 2026-02-18 Zhanliang Wang , Da Wu , Quan Nguyen , Zhuoran Xu , Kai Wang

The importance of recommender systems is growing rapidly due to the exponential increase in the volume of content generated daily. This surge in content presents unique challenges for designing effective recommender systems. Key among these…

Computation and Language · Computer Science 2025-06-12 Jiahao Tian , Jinman Zhao , Zhenkai Wang , Zhicheng Ding

Clinical decision-making reflects diverse strategies shaped by regional patient populations and institutional protocols. However, most existing medical artificial intelligence (AI) models are trained on highly prevalent data patterns, which…

Aligning language models (LMs) to human preferences has emerged as a critical pursuit, enabling these models to better serve diverse user needs. Existing methods primarily focus on optimizing LMs for a single reward function, limiting their…

Machine Learning · Computer Science 2024-10-29 Ruizhe Shi , Yifang Chen , Yushi Hu , Alisa Liu , Hannaneh Hajishirzi , Noah A. Smith , Simon S. Du

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Multi-modal learning relates information across observation modalities of the same physical phenomenon to leverage complementary information. Most multi-modal machine learning methods require that all the modalities used for training are…

Machine Learning · Computer Science 2021-03-10 Vandana Rajan , Alessio Brutti , Andrea Cavallaro

The combination of electronic health records (EHR) and medical images is crucial for clinicians in making diagnoses and forecasting prognosis. Strategically fusing these two data modalities has great potential to improve the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Wenfang Yao , Kejing Yin , William K. Cheung , Jia Liu , Jing Qin

Understanding human perceptions presents a formidable multimodal challenge for computers, encompassing aspects such as sentiment tendencies and sense of humor. While various methods have recently been introduced to extract…

Multimedia · Computer Science 2023-11-21 Hao Sun , Ziwei Niu , Xinyao Yu , Jiaqing Liu , Yen-Wei Chen , Lanfen Lin

Recent research has explored using Large Language Models for recommendation tasks by transforming user interaction histories and item metadata into text prompts, then having the LLM produce rankings or recommendations. A promising approach…

Information Retrieval · Computer Science 2025-10-03 Bo Ma , LuYao Liu , Simon Lau , Chandler Yuan , and XueY Cui , Rosie Zhang

Large language models (LLMs) have garnered unprecedented advancements across diverse fields, ranging from natural language processing to computer vision and beyond. The prowess of LLMs is underpinned by their substantial model size,…

Machine Learning · Computer Science 2025-04-10 Weilin Cai , Juyong Jiang , Fan Wang , Jing Tang , Sunghun Kim , Jiayi Huang

Accurate Intensive Care Unit (ICU) outcome prediction is critical for improving patient treatment quality and ICU resource allocation. Existing research mainly focuses on structured data, e.g. demographics and vital signs, and lacks…

Information Theory · Computer Science 2025-02-26 Yucheng Ruan , Daniel J. Tan , See Kiong Ng , Ling Huang , Mengling Feng

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Linear mixed-effects model (LMM) is a cornerstone of longitudinal data analysis, but is limited to adeptly make heterogeneous analyses predictable under both group-specific fixed effects and subject-specific random effects. To address this…

Methodology · Statistics 2026-03-10 Xinkai Yue , Xiaodong Yan , Haohui Han , Liya Fu

To enhance the interpretability of multimodal unified representations, many studies have focused on discrete unified representations. These efforts typically start with contrastive learning and gradually extend to the disentanglement of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Hai Huang , Yan Xia , Shengpeng Ji , Shulei Wang , Hanting Wang , Minghui Fang , Jieming Zhu , Zhenhua Dong , Sashuai Zhou , Zhou Zhao

Many vision-related tasks benefit from reasoning over multiple modalities to leverage complementary views of data in an attempt to learn robust embedding spaces. Most deep learning-based methods rely on a late fusion technique whereby…

Computer Vision and Pattern Recognition · Computer Science 2020-03-04 Austin Reiter , Menglin Jia , Pu Yang , Ser-Nam Lim

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Donggeun Kim , Taesup Kim

Recently, there has been growing interest in incorporating textual information into foundation models for time series forecasting. However, it remains unclear whether and under what conditions such multimodal integration consistently yields…

Recent advancements in Multimodal Large Language Models (LLMs) have focused primarily on scaling by increasing text-image pair data and enhancing LLMs to improve performance on multimodal tasks. However, these scaling approaches are…

Computer Vision and Pattern Recognition · Computer Science 2024-05-10 Jiachen Li , Xinyao Wang , Sijie Zhu , Chia-Wen Kuo , Lu Xu , Fan Chen , Jitesh Jain , Humphrey Shi , Longyin Wen

To acquire instruction-following capabilities, large language models (LLMs) undergo instruction tuning, where they are trained on instruction-response pairs using next-token prediction (NTP). Efforts to improve instruction tuning often…

Computation and Language · Computer Science 2026-04-21 Yuxin Xiao , Shujian Zhang , Wenxuan Zhou , Marzyeh Ghassemi , Sanqiang Zhao
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