English
Related papers

Related papers: A self-supervised framework for learning whole sli…

200 papers

Accurate diagnosis of pediatric brain tumors, starting with histopathology, presents unique challenges for deep learning, including severe data scarcity, class imbalance, and fine-grained morphologic overlap across diagnostically distinct…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Joakim Nguyen , Jian Yu , Jinrui Fang , Nicholas Konz , Tianlong Chen , Sanjay Krishnan , Chandra Krishnan , Ying Ding , Hairong Wang , Ankita Shukla

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Pathology foundation models (PFMs) have emerged as powerful tools for analyzing whole slide images (WSIs). However, adapting these pretrained PFMs for specific clinical tasks presents considerable challenges, primarily due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Neeraj Kumar , Swaraj Nanda , Siddharth Singi , Jamal Benhamida , David Kim , Jie-Fu Chen , Amir Momeni-Boroujeni , Gregory M. Goldgof , Gabriele Campanella , Chad Vanderbilt

The difficulty of processing gigapixel whole slide images (WSIs) in clinical microscopy has been a long-standing barrier to implementing computer aided diagnostic systems. Since modern computing resources are unable to perform computations…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Sam Maksoud , Kun Zhao , Peter Hobson , Anthony Jennings , Brian Lovell

Whole Slide Imaging (WSI) has become an important topic during the last decade. Even though significant progress in both medical image processing and computational resources has been achieved, there are still problems in WSI that need to be…

Image and Video Processing · Electrical Eng. & Systems 2019-03-19 Wafa Chenni , Habib Herbi , Morteza Babaie , H. R. Tizhoosh

In medical image analysis, the cost of acquiring high-quality data and their annotation by experts is a barrier in many medical applications. Most of the techniques used are based on supervised learning framework and need a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Siladittya Manna , Saumik Bhattacharya , Umapada Pal

Generating diagnostic text from histopathology whole slide images (WSIs) is challenging due to the gigapixel scale of the input and the requirement for precise, domain specific language. We propose a hierarchical vision language framework…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Ahmet Halici , Ece Tugba Cebeci , Musa Balci , Mustafa Cini , Serkan Sokmen

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

Microscopic assessment of histopathology images is vital for accurate cancer diagnosis and treatment. Whole Slide Image (WSI) classification and captioning have become crucial tasks in computer-aided pathology. However, microscopic WSI face…

Computer Vision and Pattern Recognition · Computer Science 2025-07-10 S M Taslim Uddin Raju , Md. Milon Islam , Md Rezwanul Haque , Hamdi Altaheri , Fakhri Karray

We introduce SPECTRE, a fully transformer-based foundation model for volumetric computed tomography (CT). Our Self-Supervised & Cross-Modal Pretraining for CT Representation Extraction (SPECTRE) approach utilizes scalable 3D Vision…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Cris Claessens , Christiaan Viviers , Giacomo D'Amicantonio , Egor Bondarev , Fons van der Sommen

Self-supervised learning methods are gaining increasing traction in computer vision due to their recent success in reducing the gap with supervised learning. In natural language processing (NLP) self-supervised learning and transformers are…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Sara Atito , Muhammad Awais , Josef Kittler

Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Minsoo Lee , Jonghyun Kim , Juseung Yun , Sunwoo Yu , Jongseong Jang

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Jiahui Li , Wen Chen , Xiaodi Huang , Zhiqiang Hu , Qi Duan , Hongsheng Li , Dimitris N. Metaxas , Shaoting Zhang

Training neural networks with high-quality pixel-level annotation in histopathology whole-slide images (WSI) is an expensive process due to gigapixel resolution of WSIs. However, recent advances in self-supervised learning have shown that…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Nohemi Sofia Leon Contreras , Marina D'Amato , Francesco Ciompi , Clement Grisi , Witali Aswolinskiy , Simona Vatrano , Filippo Fraggetta , Iris Nagtegaal

Deep learning has become the mainstream methodological choice for analyzing and interpreting whole-slide digital pathology images (WSIs). It is commonly assumed that tumor regions carry most predictive information. In this paper, we…

Quantitative Methods · Quantitative Biology 2022-04-26 Zihan Chen , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

Multiple instance learning (MIL) has become a standard paradigm for the weakly supervised classification of whole slide images (WSIs). However, this paradigm relies on using a large number of labeled WSIs for training. The lack of training…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Minghao Han , Linhao Qu , Dingkang Yang , Xukun Zhang , Xiaoying Wang , Lihua Zhang

Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang