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Flow matching as a paradigm of generative model achieves notable success across various domains. However, existing methods use either multi-round training or knowledge within minibatches, posing challenges in finding a favorable coupling…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Siyu Xing , Jie Cao , Huaibo Huang , Haichao Shi , Xiao-Yu Zhang

This paper introduces Discrete Markov Probabilistic Models (DMPMs), a novel discrete diffusion algorithm for discrete data generation. The algorithm operates in discrete bit space, where the noising process is a continuous-time Markov chain…

Machine Learning · Statistics 2025-10-09 Le-Tuyet-Nhi Pham , Dario Shariatian , Antonio Ocello , Giovanni Conforti , Alain Durmus

High-dimensional count data arise in applications such as single-cell RNA sequencing and neural spike trains, where mapping between distributions across successive batches or time points form critical components of data analysis. The recent…

Machine Learning · Statistics 2026-05-11 Ganchao Wei , John Pearson

The bifurcation of generative modeling into autoregressive approaches for discrete data (text) and diffusion approaches for continuous data (images) hinders the development of truly unified multimodal systems. While Masked Language Models…

Computation and Language · Computer Science 2026-01-08 Yuanfeng Xu , Yuhao Chen , Liang Lin , Guangrun Wang

Graph-structured data jointly contain discrete topology and continuous geometry, which poses fundamental challenges for generative modeling due to heterogeneous distributions, incompatible noise dynamics, and the need for equivariant…

Machine Learning · Computer Science 2026-04-10 Rongjian Xu , Teng Pang , Zhiqiang Dong , Guoqiang Wu

Diffusion-based generative models have recently emerged as powerful solutions for high-quality synthesis in multiple domains. Leveraging the bidirectional Markov chains, diffusion probabilistic models generate samples by inferring the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Mengyi Zhao , Mengyuan Liu , Bin Ren , Shuling Dai , Nicu Sebe

Discrete diffusion models (DDMs) are a powerful class of generative models for categorical data, but they typically require many function evaluations for a single sample, making inference expensive. Existing acceleration methods either rely…

Machine Learning · Computer Science 2025-12-16 Yansong Gao , Yu Sun

Generating long, high-quality videos remains a challenge due to the complex interplay of spatial and temporal dynamics and hardware limitations. In this work, we introduce MaskFlow, a unified video generation framework that combines…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Michael Fuest , Vincent Tao Hu , Björn Ommer

Deep generative models have made rapid progress in image, text, audio, and video generation, and are increasingly being applied to structured records. For tabular data, however, generative modeling remains difficult: a dataset may contain…

Machine Learning · Computer Science 2026-05-25 Zhong Li , Qi Huang , Lincen Yang , Jiayang Shi , Zhao Yang , Niki van Stein , Thomas Bäck , Matthijs van Leeuwen

Machine learning has demonstrated remarkable promise for solving the trajectory generation problem and in paving the way for online use of trajectory optimization for resource-constrained spacecraft. However, a key shortcoming in current…

Robotics · Computer Science 2025-01-03 Julia Briden , Breanna Johnson , Richard Linares , Abhishek Cauligi

The emergence of generative models enables the creation of texts and images tailored to users' preferences. Existing personalized generative models have two critical limitations: lacking a dedicated paradigm for accurate preference…

Information Retrieval · Computer Science 2026-04-23 Yuting Zhang , Ying Sun , Dazhong Shen , Ziwei Xie , Feng Liu , Changwang Zhang , Xiang Liu , Jun Wang , Hui Xiong

Discrete Flow-based Models (DFMs) are powerful generative models for high-quality discrete data but typically suffer from slow sampling speeds due to their reliance on iterative decoding processes. This reliance on a multi-step process…

Machine Learning · Computer Science 2025-10-21 Jaehoon Yoo , Wonjung Kim , Seunghoon Hong

In artificial intelligence (AI), especially deep learning, data diversity and volume play a pivotal role in model development. However, training a robust deep learning model often faces challenges due to data privacy, regulations, and the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Xiao Chen , Shunan Zhang , Eric Z. Chen , Yikang Liu , Lin Zhao , Terrence Chen , Shanhui Sun

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Diffusion models (DMs) are a class of generative machine learning methods that sample a target distribution by transforming samples of a trivial (often Gaussian) distribution using a learned stochastic differential equation. In standard…

Statistical Mechanics · Physics 2024-08-15 Luke Causer , Grant M. Rotskoff , Juan P. Garrahan

This work introduces the generative fractional diffusion model for protein generation (ProT-GFDM), a novel generative framework that employs fractional stochastic dynamics for protein backbone structure modeling. This approach builds on the…

Quantitative Methods · Quantitative Biology 2025-05-01 Xiao Liang , Wentao Ma , Eric Paquet , Herna Lydia Viktor , Wojtek Michalowski

Generating molecular graphs is crucial in drug design and discovery but remains challenging due to the complex interdependencies between nodes and edges. While diffusion models have demonstrated their potentiality in molecular graph design,…

Machine Learning · Computer Science 2024-11-11 Xiaoyang Hou , Tian Zhu , Milong Ren , Dongbo Bu , Xin Gao , Chunming Zhang , Shiwei Sun

Discrete diffusion and flow matching models capture complex, non-additive and non-autoregressive structure in high-dimensional objective landscapes through parallel, iterative refinement. However, their implicit generative nature precludes…

Machine Learning · Computer Science 2026-03-03 Yashvir S. Grewal , Daniel M. Steinberg , Thang D. Bui , Cheng Soon Ong , Edwin V. Bonilla

Dataset distillation compresses large datasets into compact synthetic sets with comparable performance in training models. Despite recent progress on diffusion-based distillation, this type of method typically depends on heuristic guidance…

Machine Learning · Computer Science 2026-02-06 Xuhui Li , Zhengquan Luo , Xiwei Liu , Yongqiang Yu , Zhiqiang Xu

Discrete diffusion models have recently shown significant progress in modeling complex data, such as natural languages and DNA sequences. However, unlike diffusion models for continuous data, which can generate high-quality samples in just…

Machine Learning · Computer Science 2025-03-20 Anji Liu , Oliver Broadrick , Mathias Niepert , Guy Van den Broeck