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Large Language Models (LLMs) demonstrate remarkable capabilities in various reasoning tasks. However, they encounter significant challenges when it comes to scientific reasoning, particularly in physics, which requires not only mathematical…

Artificial Intelligence · Computer Science 2024-12-03 Raj Jaiswal , Dhruv Jain , Harsh Parimal Popat , Avinash Anand , Abhishek Dharmadhikari , Atharva Marathe , Rajiv Ratn Shah

Large language models (LLMs) have made significant advancements in natural language processing (NLP). Broad corpora capture diverse patterns but can introduce irrelevance, while focused corpora enhance reliability by reducing misleading…

Large language models (LLMs) enable strong text generation, and in general there is a practical tradeoff between fine-tuning and prompt engineering. We introduce Simplify-This, a comparative study evaluating both paradigms for text…

Computation and Language · Computer Science 2026-01-12 Eilam Cohen , Itamar Bul , Danielle Inbar , Omri Loewenbach

Large language models (LLMs) have demonstrated remarkable proficiency in machine translation (MT), even without specific training on the languages in question. However, translating rare words in low-resource or domain-specific contexts…

Computation and Language · Computer Science 2024-11-14 Shangfeng Chen , Xiayang Shi , Pu Li , Yinlin Li , Jingjing Liu

Parameter-efficient transfer learning (PETL) is proposed as a cost-effective way to transfer pre-trained models to downstream tasks, avoiding the high cost of updating entire large-scale pre-trained models (LPMs). In this work, we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Yijin Huang , Pujin Cheng , Roger Tam , Xiaoying Tang

Human annotation of training samples is expensive, laborious, and sometimes challenging, especially for Natural Language Processing (NLP) tasks. To reduce the labeling cost and enhance the sample efficiency, Active Learning (AL) technique…

Computation and Language · Computer Science 2024-01-17 Xuesong Wang

Extracting sections from clinical notes is crucial for downstream analysis but is challenging due to variability in formatting and labor-intensive nature of manual sectioning. While proprietary large language models (LLMs) have shown…

Computation and Language · Computer Science 2025-01-27 Joshua Davis , Thomas Sounack , Kate Sciacca , Jessie M Brain , Brigitte N Durieux , Nicole D Agaronnik , Charlotta Lindvall

Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Zhenzhen Wang , Carla Saoud , Sintawat Wangsiricharoen , Aaron W. James , Aleksander S. Popel , Jeremias Sulam

Background: Structured information extraction from unstructured histopathology reports facilitates data accessibility for clinical research. Manual extraction by experts is time-consuming and expensive, limiting scalability. Large language…

Prompt design plays a critical role in the reasoning performance of large language models (LLMs), yet the impact of prompt specificity - how detailed or vague a prompt is - remains understudied. This paper introduces DETAIL, a framework for…

Computation and Language · Computer Science 2025-12-03 Olivia Kim

Purpose To evaluate the reasoning capabilities of large language models (LLMs) in performing root cause analysis (RCA) of radiation oncology incidents using narrative reports from the Radiation Oncology Incident Learning System (RO-ILS),…

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

This paper introduces a novel paradigm for depression detection and treatment using advanced Large Language Models (LLMs): Generative Pre-trained Transformer 4 (GPT-4), Llama 2 chat, and Gemini. These LLMs are fine-tuned with specialized…

Computation and Language · Computer Science 2024-02-09 Aryan Agrawal

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Chemotherapy for cancer treatment is costly and accompanied by severe side effects, highlighting the critical need for early prediction of treatment outcomes to improve patient management and informed decision-making. Predictive models for…

Fine-tuning pre-trained language models (PLMs), e.g., SciBERT, generally requires large numbers of annotated data to achieve state-of-the-art performance on a range of NLP tasks in the scientific domain. However, obtaining the fine-tune…

Computation and Language · Computer Science 2025-12-30 Jiawei Liu , Zi Xiong , Yi Jiang , Yongqiang Ma , Wei Lu , Yong Huang , Qikai Cheng

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

Computation and Language · Computer Science 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

While Large Language Models (LLMs) are being quickly adapted to many domains, including healthcare, their strengths and pitfalls remain under-explored. In our study, we examine the effects of prompt engineering to guide Large Language…

Computation and Language · Computer Science 2024-09-04 Daniil Filienko , Yinzhou Wang , Caroline El Jazmi , Serena Xie , Trevor Cohen , Martine De Cock , Weichao Yuwen

Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

Computation and Language · Computer Science 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas

This study examines the effect of prompt engineering on the performance of Large Language Models (LLMs) in clinical note generation. We introduce an Automatic Prompt Optimization (APO) framework to refine initial prompts and compare the…

Computation and Language · Computer Science 2024-07-08 Zonghai Yao , Ahmed Jaafar , Beining Wang , Zhichao Yang , Hong Yu