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Large Language Models (LLMs) offer significant potential for clinical symptom extraction, but their deployment in healthcare settings is constrained by privacy concerns, computational limitations, and operational costs. This study…

Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes. Despite their vital role, no current oncology…

Computation and Language · Computer Science 2024-03-18 Madhumita Sushil , Vanessa E. Kennedy , Divneet Mandair , Brenda Y. Miao , Travis Zack , Atul J. Butte

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

This work presents our participation in the EvalLLM 2025 challenge on biomedical Named Entity Recognition (NER) and health event extraction in French (few-shot setting). For NER, we propose three approaches combining large language models…

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…

Natural language processing (NLP) is a key technology to extract important patient information from clinical narratives to support healthcare applications. The rapid development of large language models (LLMs) has revolutionized many NLP…

Computation and Language · Computer Science 2025-09-08 Cheng Peng , Xinyu Dong , Mengxian Lyu , Daniel Paredes , Yaoyun Zhang , Yonghui Wu

We evaluated the viability of using a Large Language Model (LLM) to extract patient-specific specific toxicity and progression outcomes from unstructured radiology reports. We retrospectively extracted 160 follow-up CT and PET/CT electronic…

Medical Physics · Physics 2026-03-02 Justin Pijanowski , Yakout Mezgueldi , Alan Lee , Drew Moghanaki , Ricky R. Savjani , James Lamb

Background: Manual extraction of pancreatic cystic lesion (PCL) features from radiology reports is labor-intensive, limiting large-scale studies needed to advance PCL research. Purpose: To develop and evaluate large language models (LLMs)…

Generating discharge summaries is a crucial yet time-consuming task in clinical practice, essential for conveying pertinent patient information and facilitating continuity of care. Recent advancements in large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-01 Yiming Li , Fang Li , Kirk Roberts , Licong Cui , Cui Tao , Hua Xu

Objective: Clinical documentation contains factual, diagnostic, and management errors that can compromise patient safety. Large language models (LLMs) may help detect and correct such errors, but their behavior under different prompting…

Computation and Language · Computer Science 2025-11-27 Farzad Ahmed , Joniel Augustine Jerome , Meliha Yetisgen , Özlem Uzuner

Background: Advancements in large language models (LLMs) have opened new possibilities in psychiatric interviews, an underexplored area where LLMs could be valuable. This study focuses on enhancing psychiatric interviews by analyzing…

Artificial Intelligence · Computer Science 2025-02-11 Jae-hee So , Joonhwan Chang , Eunji Kim , Junho Na , JiYeon Choi , Jy-yong Sohn , Byung-Hoon Kim , Sang Hui Chu

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

Tumor documentation in Germany is largely done manually, requiring reading patient records and entering data into structured databases. Large language models (LLMs) could potentially enhance this process by improving efficiency and…

Computation and Language · Computer Science 2025-08-08 Stefan Lenz , Arsenij Ustjanzew , Marco Jeray , Meike Ressing , Torsten Panholzer

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Large language models (LLMs) have become increasingly capable of following instructions and complex reasoning, making prompting a flexible interface for adapting models without parameter updates. Yet prompt design remains labor-intensive…

Computation and Language · Computer Science 2026-05-22 Farima Fatahi Bayat , Moin Aminnaseri , Pouya Pezeshkpour , Estevam Hruschka

We investigate different natural language processing (NLP) approaches based on contextualised word representations for the problem of early prediction of lung cancer using free-text patient medical notes of Dutch primary care physicians.…

Computation and Language · Computer Science 2023-03-29 Auke Elfrink , Iacopo Vagliano , Ameen Abu-Hanna , Iacer Calixto

OpenNotes enables patients to access EHR notes, but medical jargon can hinder comprehension. To improve understanding, we evaluated closed- and open-source LLMs for extracting and prioritizing key medical terms using prompting, fine-tuning,…

Computation and Language · Computer Science 2026-05-08 Won Seok Jang , Sharmin Sultana , Zonghai Yao , Hieu Tran , Zhichao Yang , Sunjae Kwon , Hong Yu

Patient experience and care quality are crucial for a hospital's sustainability and reputation. The analysis of patient feedback offers valuable insight into patient satisfaction and outcomes. However, the unstructured nature of these…

Computation and Language · Computer Science 2025-02-21 Hajar Sakai , Sarah S. Lam , Mohammadsadegh Mikaeili , Joshua Bosire , Franziska Jovin

Recent advances have greatly increased the capabilities of large language models (LLMs), but our understanding of the models and their safety has not progressed as fast. In this paper we aim to understand LLMs deeper by studying their…

Computation and Language · Computer Science 2023-10-12 Justin Lee , Tuomas Oikarinen , Arjun Chatha , Keng-Chi Chang , Yilan Chen , Tsui-Wei Weng

Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

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