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The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

One of the most difficult problems difficult problem in systems biology is to discover protein-protein interactions as well as their associated functions. The analysis and alignment of protein-protein interaction networks (PPIN), which are…

Molecular Networks · Quantitative Biology 2019-02-20 Ricardo Alberich , Adrià Alcala , Mercè Llabrés , Francesc Rosselló , Gabriel Valiente

Extended reality (XR), encompassing Virtual Reality (VR), Augmented Reality (AR), and Mixed Reality (MR), is emerging as a transformative platform for medical education. Traditional methods such as textbooks, physical models, and cadaveric…

Human-Computer Interaction · Computer Science 2025-09-03 Yuqing Wei , Yupeng Wang , Jiayi Zhao , Yanjun Liu , Huxin Gao , Jiewen Lai

Visual place recognition (VPR) is a robot's ability to determine whether a place was visited before using visual data. While conventional hand-crafted methods for VPR fail under extreme environmental appearance changes, those based on…

Computer Vision and Pattern Recognition · Computer Science 2022-03-07 Bruno Ferrarini , Michael Milford , Klaus D. McDonald-Maier , Shoaib Ehsan

Network analysis has been applied in diverse application domains. In this paper, we consider an example from protein dynamics, specifically residue interaction networks (RINs). In this context, we use NetworKit -- an established package for…

Social and Information Networks · Computer Science 2022-03-03 Eugenio Angriman , Fabian Brandt-Tumescheit , Leon Franke , Alexander van der Grinten , Henning Meyerhenke

Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying dynamics of biological systems from sparse experimental data. In the present work, BINNs…

Quantitative Methods · Quantitative Biology 2021-01-27 John H. Lagergren , John T. Nardini , Ruth E. Baker , Matthew J. Simpson , Kevin B. Flores

Prediction of protein-ligand interactions (PLI) plays a crucial role in drug discovery as it guides the identification and optimization of molecules that effectively bind to target proteins. Despite remarkable advances in deep…

Biomolecules · Quantitative Biology 2023-07-18 Seokhyun Moon , Sang-Yeon Hwang , Jaechang Lim , Woo Youn Kim

Hybrid mixed-reality (XR) internet-of-things (IoT) research, here called XRI, aims at a strong integration between physical and virtual objects, environments, and agents wherein IoT-enabled edge devices are deployed for sensing, context…

Human-Computer Interaction · Computer Science 2023-06-05 Jie Guan , Alexis Morris

While significant advancements in artificial intelligence (AI) have catalyzed progress across various domains, its full potential in understanding visual perception remains underexplored. We propose an artificial neural network dubbed…

Computer Vision and Pattern Recognition · Computer Science 2023-09-27 Ruixing Liang , Xiangyu Zhang , Qiong Li , Lai Wei , Hexin Liu , Avisha Kumar , Kelley M. Kempski Leadingham , Joshua Punnoose , Leibny Paola Garcia , Amir Manbachi

Simulating the complex interactions between soft tissues and rigid anatomy is critical for applications in surgical training, planning, and robotic-assisted interventions. Traditional Finite Element Method (FEM)-based simulations, while…

Robotics · Computer Science 2025-08-05 Xintian Yuan , Yunke Ao , Boqi Chen , Philipp Fuernstahl

Deep learning-based computational methods have achieved promising results in predicting protein-protein interactions (PPIs). However, existing benchmarks predominantly focus on isolated pairwise evaluations, overlooking a model's capability…

Machine Learning · Computer Science 2025-10-23 Xinzhe Zheng , Hao Du , Fanding Xu , Jinzhe Li , Zhiyuan Liu , Wenkang Wang , Tao Chen , Wanli Ouyang , Stan Z. Li , Yan Lu , Nanqing Dong , Yang Zhang

Visualizations are an essential part of biomedical analysis result interpretation. Often, interactive networks are used to visualize the data. However, the high interconnectivity, and high dimensionality of the data often results in…

Graphics · Computer Science 2021-09-08 Álvaro Martínez Fernández , Lars Ailo Bongo , Edvard Pedersen

The prospect of 4D video in Extended Reality (XR) platform is huge and exciting, it opens a whole new way of human computer interaction and the way we perceive the reality and consume multimedia. In this thesis, we have shown that…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Karthik Shivashankar

Network visualizations are commonly used to analyze relationships in various contexts. To efficiently explore a network visualization, the user needs to quickly navigate to different parts of the network and analyze local details. Recent…

Human-Computer Interaction · Computer Science 2023-03-29 Helen H. Huang , Hanspeter Pfister , Yalong Yang

Three-dimensional (3D) shape recognition has drawn much research attention in the field of computer vision. The advances of deep learning encourage various deep models for 3D feature representation. For point cloud and multi-view data, two…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Haoxuan You , Yifan Feng , Xibin Zhao , Changqing Zou , Rongrong Ji , Yue Gao

For over half a century, the computer mouse has been the primary tool for interacting with digital data, yet it remains a limiting factor in exploring complex, multi-scale scientific images. Traditional 2D visualization methods hinder…

Determining the localization of specific protein in human cells is important for understanding cellular functions and biological processes of underlying diseases. Among imaging techniques, high-throughput fluorescence microscopy imaging is…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Yijun Tian

This paper presents BioNeRF, a biologically plausible architecture that models scenes in a 3D representation and synthesizes new views through radiance fields. Since NeRF relies on the network weights to store the scene's 3-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Leandro A. Passos , Douglas Rodrigues , Danilo Jodas , Kelton A. P. Costa , Ahsan Adeel , João Paulo Papa

Bionic vision is a rapidly advancing field aimed at developing visual neuroprostheses ('bionic eyes') to restore useful vision to people who are blind. However, a major outstanding challenge is predicting what people 'see' when they use…

Human-Computer Interaction · Computer Science 2021-02-23 Justin Kasowski , Nathan Wu , Michael Beyeler

We present a collaborative extended reality (XR) prototype for 3D surgical planning and visualization. Our system consists of three key modules: XR-based immersive surgical planning, cloud-based data management, and coordinated stereoscopic…

Human-Computer Interaction · Computer Science 2026-01-28 Shi Qiu , Ruiyang Li , Qixuan Liu , Yuqi Tong , Yue Qiu , Yinqiao Wang , Yan Li , Chi-Wing Fu , Pheng-Ann Heng