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Multilayer networks are widely used across biology to represent systems in which complex networks vary across space, time, or interaction types. However, interactive visualization tools remain limited. We present MiRA (Multilayer…

Social and Information Networks · Computer Science 2026-05-14 Shir Miryam Nehoray , Yuval Bloch , Shai Pilosof

Protein-ligand scoring is an important step in a structure-based drug design pipeline. Selecting a correct binding pose and predicting the binding affinity of a protein-ligand complex enables effective virtual screening. Machine learning…

Machine Learning · Statistics 2020-10-19 Joshua Hochuli , Alec Helbling , Tamar Skaist , Matthew Ragoza , David Ryan Koes

The ability to precisely visualize the atomic geometry of the interactions between a drug and its protein target in structural models is critical in predicting the correct modifications in previously identified inhibitors to create more…

Biomolecules · Quantitative Biology 2018-08-14 Erick Martins Ratamero , Dom Bellini , Christopher G. Dowson , Rudolf A. Roemer

Visualization plays a vital role in making sense of complex network data. Recent studies have shown the potential of using extended reality (XR) for the immersive exploration of networks. The additional depth cues offered by XR help users…

Human-Computer Interaction · Computer Science 2023-01-27 David Bauer , Chengbo Zheng , Oh-Hyun Kwon , Kwan-Liu Ma

The identification of essential proteins in protein-protein interaction networks (PINs) can help to discover drug targets and prevent disease. In order to improve the accuracy of the identification of essential proteins, researchers…

Molecular Networks · Quantitative Biology 2023-12-08 Haoyue Wang , Li Pan , Bo Yang , Junqiang Jiang , Wenbin Li

ASCRIBE-XR, a novel computational platform designed to facilitate the visualization and exploration of 3D volumetric data and mesh data in the context of synchrotron experiments, is described. Using Godot and PC-VR technologies, the…

Human-Computer Interaction · Computer Science 2025-07-08 Ronald J. Pandolfi , Jeffrey J. Donatelli , Julian Todd , Daniela Ushizima

Researching novel user experiences in medicine is challenging due to limited access to equipment and strict ethical protocols. Extended Reality (XR) simulation technologies offer a cost- and time-efficient solution for developing…

Human-Computer Interaction · Computer Science 2024-09-17 Jan Hendrik Plümer , Kevin Yu , Ulrich Eck , Denis Kalkofen , Philipp Steininger , Nassir Navab , Markus Tatzgern

Protein complexes are macromolecules essential to the functioning and well-being of all living organisms. As the structure of a protein complex, in particular its region of interaction between multiple protein subunits (i.e., chains), has a…

Machine Learning · Computer Science 2022-05-26 Alex Morehead , Xiao Chen , Tianqi Wu , Jian Liu , Jianlin Cheng

In this and the associated article 'BioBlender: A Software for Intuitive Representation of Surface Properties of Biomolecules', (Andrei et al) we present BioBlender as a complete instrument for the elaboration of motion (here) and the…

Biomolecules · Quantitative Biology 2010-09-27 Maria Francesca Zini , Yuri Porozov , Raluca Mihaela Andrei , Tiziana Loni , Claudia Caudai , Monica Zoppè

Visual neuroprostheses are commonly framed as technologies to restore natural sight to people who are blind. In practice, they create a novel mode of perception shaped by sparse, distorted, and unstable input. They resemble early extended…

Emerging Technologies · Computer Science 2025-08-11 Michael Beyeler

In this and the associated article 'BioBlender: Fast and Efficient All Atom Morphing of Proteins Using Blender Game Engine', by Zini et al., we present BioBlender, a complete instrument for the elaboration of motion (Zini et al.) and the…

The core idea in an XR (VR/MR/AR) application is to digitally stimulate one or more sensory systems (e.g. visual, auditory, olfactory) of the human user in an interactive way to achieve an immersive experience. Since the early 2000s…

Graphics · Computer Science 2020-02-26 Hemal Naik , Renaud Bastien , Nassir Navab , Iain Couzin

We provide a visualization model that targets the visualization of Protein-Protein Interactions(PPI) and combines it with a super view based on publications and methods to extract interactions. Although there are several existing tools, our…

Information Retrieval · Computer Science 2021-11-29 Melih Sozdinler

Molecular visualization software has long supported research and education in chemical and structural sciences, but consumer devices constrained to 2D inputs and outputs pose two major challenges: they poorly convey 3D nature, and 3D…

Chemical Physics · Physics 2025-09-05 Luciano A. Abriata

Protein structure representation is an important tool in structural biology. There exists different methods of representing the protein 3D structures and different biologists favor different methods based on the information they require.…

Biomolecules · Quantitative Biology 2016-02-29 Vrunda Sheth , Vicente M. Reyes

Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar

Rendering realistic images from 3D reconstruction is an essential task of many Computer Vision and Robotics pipelines, notably for mixed-reality applications as well as training autonomous agents in simulated environments. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Lukas Bösiger , Mihai Dusmanu , Marc Pollefeys , Zuria Bauer

Extended reality (XR) technologies-encompassing virtual reality (VR), augmented reality (AR), and mixed reality (MR) are transforming cognitive assessment and training by offering immersive, interactive environments that simulate real-world…

Human-Computer Interaction · Computer Science 2025-01-15 Palmira Victoria González-Erena , Sara Fernández-Guinea , Panagiotis Kourtesis

Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

Quantitative Methods · Quantitative Biology 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…

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