English
Related papers

Related papers: Proton-CAT: a Novel Strategy for Enhanced Proton T…

200 papers

Proton radiography combined with X-ray computed tomography (CT) has been proposed to obtain a patient-specific calibration curve and reduce range uncertainties in cancer treatment with charged particles. The main aim of this study was to…

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

High-quality proton beams generated by laser-plasma interactions are of significant interest for applications ranging from tumor therapy to fast ignition in inertial confinement fusion. However, simultaneously achieving high energy coupling…

Plasma Physics · Physics 2026-03-17 Cheng-Qi Zhang , Yang He , Mamat Ali Bake , Bai-Song Xie

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. Real-time range…

Medical Physics · Physics 2018-10-17 Kristian Smeland Ytre-Hauge , Kyrre Skjerdal , John Mattingly , Ilker Meric

Proton therapy is an emerging method in cancer therapy. One of the main developments is to increase the accuracy of the Bragg-peak position calculation, which requires more precise relative stopping power (RSP) measurements. A promising…

Medical Physics · Physics 2026-02-18 Gábor Bíró , Ákos Sudár , Zsófia Jólesz , Gábor Papp , Gergely Gábor Barnaföldi

Proton therapy offers significant advantages due to its unique physical and biological properties, particularly the Bragg peak, enabling precise dose delivery to tumors while sparing healthy tissues. However, the clinical implementation is…

The paper discusses some 3D simulations to compute the ionizing radiation dose during laser-plasma experiments leading to the generation of accelerated protons and electrons. Also, we suggest a new method to increase the measurement…

Instrumentation and Detectors · Physics 2019-10-02 M. Ganciu , A. Chirosca , A. Groza , E. Stancu , O. Stoican , D. B. Dreghici , B. Butoi , C. Ticos , B. Mihalcea , B. Cramariuc

The aim of this study is to investigate the dose-deposition enhancement by alpha-particle irradiation in a cellular model using carbon and oxygen chemical compositions.A simulation study was performed to study dose enhancement due to carbon…

Boron Neutron Capture Therapy (BNCT), is an advanced cancer therapy that destroys the cancer tumors using the well-known Li(p,n)Be . Because of the highly selectively reaction between a boron and a neutron, BNCT is effective for rapidly…

Accelerator Physics · Physics 2016-09-21 Zhu Xiaowen , Lu Yuanrong , Zhu Kun

Improving effective treatment plans in carbon ion therapy, especially for targeting radioresistant tumors located in deep seated regions while sparing normal tissues, depends on a precise and computationally efficient dose calculation…

Medical Physics · Physics 2025-06-25 Fulya Halıcılar , Metin Arık

Boron Neutron Capture Therapy (BNCT) is a neutron radiotherapy used to treat tumours cells previously doping with Boron-10. This therapy requires an epithermal neutron beam for the treatment of deep tumours and a thermal beam for shallow…

Instrumentation and Detectors · Physics 2021-06-02 M. Macías , B. Fernández , J. Praena

Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

Reducing proton treatment time improves patient comfort and decreases the risk of error from intra-fractional motion, but must be balanced against clinical goals and treatment plan quality. We formulated the proton treatment planning…

Medical Physics · Physics 2024-04-26 Anqi Fu , Vicki T. Taasti , Masoud Zarepisheh

This comprehensive study delves into the intricate interplay between protons and organic polymers, offering insights into proton therapy in cancer treatment. Focusing on the influence of the spatial electron density distribution on stopping…

Proton interactions with $^{12}$C nuclei are a frequent nuclear interaction leading to secondary radiation in tissues for space radiation and cancer therapy with protons or $^{12}$C beams. The fragmentation of $^{12}$C by protons produces a…

Nuclear Theory · Physics 2022-11-30 Francis A. Cucinotta , Sungmin Pak

Objective: Proton spot-scanning arc therapy (ARC) is an emerging modality that can improve the high-dose conformity to targets compared with standard intensity-modulated proton therapy (IMPT). However, the efficient treatment delivery of…

Aneutronic and nonradioactive properties make the proton-boron fusion a prospective candidate for fusion energy production through reactions following p+$^{11}$B$\rightarrow$3${\alpha}$ (p-$^{11}$B). However, it is difficult to achieve a…

Secondary radiation in a radiation therapy environment is considered a cause for post-treatment side effects including secondary carcinogenesis. In a proton-therapy setup, neutrons deliver a considerable extra dose to the patient. Various…

Medical Physics · Physics 2022-11-16 Nima Tatari