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Motivated by applications in personalized medicine and individualized policymaking, there is a growing interest in techniques for quantifying treatment effect heterogeneity in terms of the conditional average treatment effect (CATE). Some…

Methodology · Statistics 2024-06-04 Pawel Morzywolek , Johan Decruyenaere , Stijn Vansteelandt

End-to-end representation learning has become a powerful tool for estimating causal quantities from high-dimensional observational data, but its efficiency remained unclear. Here, we face a central tension: End-to-end representation…

Machine Learning · Computer Science 2026-04-28 Valentyn Melnychuk , Dennis Frauen , Jonas Schweisthal , Stefan Feuerriegel

Orthogonal meta-learners, such as DR-learner, R-learner and IF-learner, are increasingly used to estimate conditional average treatment effects. They improve convergence rates relative to na\"{\i}ve meta-learners (e.g., T-, S- and…

Methodology · Statistics 2023-11-17 Stijn Vansteelandt , Paweł Morzywołek

Estimating conditional average treatment effects (CATE) from observational data involves modeling decisions that differ from supervised learning, particularly concerning how to regularize model complexity. Previous approaches can be grouped…

Machine Learning · Computer Science 2026-02-03 Zhongyuan Liang , Lars van der Laan , Ahmed Alaa

A key challenge in e-learning environments like Intelligent Tutoring Systems (ITSs) is to induce effective pedagogical policies efficiently. While Deep Reinforcement Learning (DRL) often suffers from sample inefficiency and reward function…

Machine Learning · Computer Science 2024-06-05 Md Mirajul Islam , Xi Yang , John Hostetter , Adittya Soukarjya Saha , Min Chi

We address the problem of estimating heterogeneous treatment effects in panel data, adopting the popular Difference-in-Differences (DiD) framework under the conditional parallel trends assumption. We propose a novel doubly robust…

Machine Learning · Statistics 2025-04-29 Hui Lan , Haoge Chang , Eleanor Dillon , Vasilis Syrgkanis

Predicting individualized potential outcomes in sequential decision-making is central for optimizing therapeutic decisions in personalized medicine (e.g., which dosing sequence to give to a cancer patient). However, predicting potential…

Estimating heterogeneous treatment effects from observational data is a crucial task across many fields, helping policy and decision-makers take better actions. There has been recent progress on robust and efficient methods for estimating…

Machine Learning · Computer Science 2023-11-09 Miruna Oprescu , Jacob Dorn , Marah Ghoummaid , Andrew Jesson , Nathan Kallus , Uri Shalit

Entity linkage (EL) is a critical problem in data cleaning and integration. In the past several decades, EL has typically been done by rule-based systems or traditional machine learning models with hand-curated features, both of which…

Databases · Computer Science 2020-12-04 Zhengyang Wang , Bunyamin Sisman , Hao Wei , Xin Luna Dong , Shuiwang Ji

Efficiently and flexibly estimating treatment effect heterogeneity is an important task in a wide variety of settings ranging from medicine to marketing, and there are a considerable number of promising conditional average treatment effect…

Machine Learning · Statistics 2023-05-10 Erik Sverdrup , Yifan Cui

Popular debiased estimation methods for causal inference -- such as augmented inverse propensity weighting and targeted maximum likelihood estimation -- enjoy desirable asymptotic properties like statistical efficiency and double robustness…

Machine Learning · Statistics 2025-09-16 Tiffany Tianhui Cai , Yuri Fonseca , Kaiwen Hou , Hongseok Namkoong

Electrocardiogram (ECG) analysis is foundational for cardiovascular disease diagnosis, yet the performance of deep learning models is often constrained by limited access to annotated data. Self-supervised contrastive learning has emerged as…

Machine Learning · Computer Science 2025-08-22 Yi Yuan , Joseph Van Duyn , Runze Yan , Zhuoyi Huang , Sulaiman Vesal , Sergey Plis , Xiao Hu , Gloria Hyunjung Kwak , Ran Xiao , Alex Fedorov

Quantifying the data uncertainty in learning tasks is often done by learning a prediction interval or prediction set of the label given the input. Two commonly desired properties for learned prediction sets are \emph{valid coverage} and…

Machine Learning · Computer Science 2022-05-31 Yu Bai , Song Mei , Huan Wang , Yingbo Zhou , Caiming Xiong

Exact inference in the linear regression model with spike and slab priors is often intractable. Expectation propagation (EP) can be used for approximate inference. However, the regular sequential form of EP (R-EP) may fail to converge in…

Machine Learning · Statistics 2011-12-13 José Miguel Hernández-Lobato , Daniel Hernández-Lobato

We introduce a novel contrastive representation learning objective and a training scheme for clinical time series. Specifically, we project high dimensional EHR. data to a closed unit ball of low dimension, encoding geometric priors so that…

Machine Learning · Computer Science 2022-07-05 Thesath Nanayakkara , Gilles Clermont , Christopher James Langmead , David Swigon

Previous deep learning efforts have focused on improving the performance of Pulmonary Embolism(PE) diagnosis from Computed Tomography (CT) scans using Convolutional Neural Networks (CNN). However, the features from CT scans alone are not…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Santosh Sanjeev , Salwa K. Al Khatib , Mai A. Shaaban , Ibrahim Almakky , Vijay Ram Papineni , Mohammad Yaqub

Medical education increasingly emphasizes students' ability to apply knowledge in real-world clinical settings, focusing on evidence-based clinical reasoning and differential diagnoses. Problem-based learning (PBL) addresses traditional…

Human-Computer Interaction · Computer Science 2025-03-11 Yuansong Xu , Yuheng Shao , Jiahe Dong , Shaohan Shi , Chang Jiang , Quan Li

The goal of policy learning is to train a policy function that recommends a treatment given covariates to maximize population welfare. There are two major approaches in policy learning: the empirical welfare maximization (EWM) approach and…

Machine Learning · Statistics 2025-11-06 Masahiro Kato

Estimating heterogeneous treatment effects (HTEs) in time-varying settings is particularly challenging, as the probability of observing certain treatment sequences decreases exponentially with longer prediction horizons. Thus, the observed…

Machine Learning · Computer Science 2026-02-12 Konstantin Hess , Dennis Frauen , Mihaela van der Schaar , Stefan Feuerriegel

Equilibrium Propagation (EP) is a powerful and more bio-plausible alternative to conventional learning frameworks such as backpropagation. The effectiveness of EP stems from the fact that it relies only on local computations and requires…

Neural and Evolutionary Computing · Computer Science 2023-08-23 Malyaban Bal , Abhronil Sengupta
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