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The extraction of relevant data from Electronic Health Records (EHRs) is crucial to identifying symptoms and automating epidemiological surveillance processes. By harnessing the vast amount of unstructured text in EHRs, we can detect…

Computation and Language · Computer Science 2025-02-10 Juliano Genari , Guilherme Tegoni Goedert

Amid rising concerns of reproducibility and generalizability in predictive modeling, we explore the possibility and potential benefits of introducing pre-registration to the field. Despite notable advancements in predictive modeling,…

Machine Learning · Computer Science 2023-12-01 Jake M. Hofman , Angelos Chatzimparmpas , Amit Sharma , Duncan J. Watts , Jessica Hullman

Electronic Health Records (EHR) are generated from clinical routine care recording valuable information of broad patient populations, which provide plentiful opportunities for improving patient management and intervention strategies in…

Machine Learning · Computer Science 2023-04-13 Changshuo Liu , Wenqiao Zhang , Beng Chin Ooi , James Wei Luen Yip , Lingze Zeng , Kaiping Zheng

Electronic Health Records (EHR)-based disease prediction models have demonstrated significant clinical value in promoting precision medicine and enabling early intervention. However, existing large language models face two major challenges:…

Computation and Language · Computer Science 2025-06-19 Junke Wang , Hongshun Ling , Li Zhang , Longqian Zhang , Fang Wang , Yuan Gao , Zhi Li

Deep learning models have demonstrated superior performance in various healthcare applications. However, the major limitation of these deep models is usually the lack of high-quality training data due to the private and sensitive nature of…

Computation and Language · Computer Science 2022-11-15 Qiuhao Lu , Dejing Dou , Thien Huu Nguyen

Recent advances in large language models (LLMs) have enabled promising progress in diagnosis prediction from electronic health records (EHRs). However, existing LLM-based approaches tend to overfit to historically observed diagnoses, often…

Computation and Language · Computer Science 2026-04-14 Hengyu Zhang , Xuyun Zhang , Pengxiang Zhan , Linhao Luo , Hang Lv , Yanchao Tan , Shirui Pan , Carl Yang

The burgeoning volume of electronic health records (EHRs) has enabled deep learning models to excel in predictive healthcare. However, for high-stakes applications such as diagnosis prediction, model interpretability remains paramount.…

Machine Learning · Computer Science 2025-05-02 Leisheng Yu , Yanxiao Cai , Minxing Zhang , Xia Hu

Health registers contain rich information about individuals' health histories. Here our interest lies in understanding how individuals' health trajectories evolve in a nationwide longitudinal dataset with coded features, such as clinical…

Machine Learning · Computer Science 2024-12-13 Hans Moen , Vishnu Raj , Andrius Vabalas , Markus Perola , Samuel Kaski , Andrea Ganna , Pekka Marttinen

Electronic Health Records (EHR) are crucial for the success of digital healthcare, with a focus on putting consumers at the center of this transformation. However, the digitalization of healthcare records brings along security and privacy…

Machine Learning · Computer Science 2024-10-07 Vinaytosh Mishra , Kishu Gupta , Deepika Saxena , Ashutosh Kumar Singh

Machine learning (ML) has recently shown promising results in medical predictions using electronic health records (EHRs). However, since ML models typically have a limited capability in terms of input sizes, selecting specific medical…

Machine Learning · Computer Science 2024-07-23 Junu Kim , Chaeeun Shim , Bosco Seong Kyu Yang , Chami Im , Sung Yoon Lim , Han-Gil Jeong , Edward Choi

Deep learning continues to rapidly evolve and is now demonstrating remarkable potential for numerous medical prediction tasks. However, realizing deep learning models that generalize across healthcare organizations is challenging. This is…

Machine Learning · Computer Science 2023-08-23 Zhuohang Li , Chao Yan , Xinmeng Zhang , Gharib Gharibi , Zhijun Yin , Xiaoqian Jiang , Bradley A. Malin

Machine learning has been widely used in healthcare applications to approximate complex models, for clinical diagnosis, prognosis, and treatment. As deep learning has the outstanding ability to extract information from time series, its true…

Machine Learning · Computer Science 2022-11-14 Ke Liao , Wei Wang , Armagan Elibol , Lingzhong Meng , Xu Zhao , Nak Young Chong

Advancements in sensing and computing technologies, the development of human and computer interaction frameworks, big data storage capabilities, and the emergence of cloud storage and could computing have resulted in an abundance of data in…

Machine Learning · Computer Science 2020-07-07 Ramin Moradi , Katrina M. Groth

This work investigates multiple approaches to Named Entity Recognition (NER) for text in Electronic Health Record (EHR) data. In particular, we look into the application of (i) rule-based, (ii) deep learning and (iii) transfer learning…

Electronic health records (EHR) are increasingly being used for constructing disease risk prediction models. Feature engineering in EHR data however is challenging due to their highly dimensional and heterogeneous nature. Low-dimensional…

Computation and Language · Computer Science 2018-11-29 Spiros Denaxas , Pontus Stenetorp , Sebastian Riedel , Maria Pikoula , Richard Dobson , Harry Hemingway

Electronic health records (EHRs) linked with familial relationship data offer a unique opportunity to investigate the genetic architecture of complex phenotypes at scale. However, existing heritability and coheritability estimation methods…

Methodology · Statistics 2025-11-12 Yinjun Zhao , Nicholas Tatonetti , Yuanjia Wang

The introduction of Large Language Models (LLMs) has advanced data representation and analysis, bringing significant progress in their use for medical questions and answering. Despite these advancements, integrating tabular data, especially…

Computation and Language · Computer Science 2024-09-23 Yanjun Gao , Skatje Myers , Shan Chen , Dmitriy Dligach , Timothy A Miller , Danielle Bitterman , Matthew Churpek , Majid Afshar

Electronic health record (EHR) data is collected by individual institutions and often stored across locations in silos. Getting access to these data is difficult and slow due to security, privacy, regulatory, and operational issues. We…

Computers and Society · Computer Science 2018-12-04 Dianbo Liu , Timothy Miller , Raheel Sayeed , Kenneth D. Mandl

Childhood obesity is a major public health challenge. Early prediction and identification of the children at a high risk of developing childhood obesity may help in engaging earlier and more effective interventions to prevent and manage…

Applications · Statistics 2022-05-03 Mehak Gupta , Thao-Ly T. Phan , Timothy Bunnell , Rahmatollah Beheshti

Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and…

Machine Learning · Statistics 2017-04-12 Trang Pham , Truyen Tran , Dinh Phung , Svetha Venkatesh