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Recent advances in generative AI have brought incredible breakthroughs in several areas, including medical imaging. These generative models have tremendous potential not only to help safely share medical data via synthetic datasets but also…

We introduce the concept of deceptive diffusion -- training a generative AI model to produce adversarial images. Whereas a traditional adversarial attack algorithm aims to perturb an existing image to induce a misclassificaton, the…

Machine Learning · Computer Science 2024-07-01 Lucas Beerens , Catherine F. Higham , Desmond J. Higham

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

Diffusion models (DMs) memorize training images and can reproduce near-duplicates during generation. Current detection methods identify verbatim memorization but fail to capture two critical aspects: quantifying partial memorization…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Jimmy Z. Di , Yiwei Lu , Yaoliang Yu , Gautam Kamath , Adam Dziedzic , Franziska Boenisch

AI-generated content has attracted lots of attention recently, but photo-realistic video synthesis is still challenging. Although many attempts using GANs and autoregressive models have been made in this area, the visual quality and length…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yingqing He , Tianyu Yang , Yong Zhang , Ying Shan , Qifeng Chen

The artificial intelligence (AI) world is running out of real data for training increasingly large generative models, resulting in accelerating pressure to train on synthetic data. Unfortunately, training new generative models with…

Machine Learning · Computer Science 2024-08-30 Sina Alemohammad , Ahmed Imtiaz Humayun , Shruti Agarwal , John Collomosse , Richard Baraniuk

Recent advancements in text-to-image diffusion models have demonstrated their remarkable capability to generate high-quality images from textual prompts. However, increasing research indicates that these models memorize and replicate images…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Jie Ren , Yaxin Li , Shenglai Zeng , Han Xu , Lingjuan Lyu , Yue Xing , Jiliang Tang

Recent research has highlighted the risk of generative model collapse, where performance progressively degrades when continually trained on self-generated data. However, existing exploration on model collapse is limited to single, unimodal…

Machine Learning · Computer Science 2025-05-15 Zizhao Hu , Mohammad Rostami , Jesse Thomason

Image-to-Image translation models can help mitigate various challenges inherent to medical image acquisition. Latent diffusion models (LDMs) leverage efficient learning in compressed latent space and constitute the core of state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Junhyeok Lee , Hyunwoong Kim , Hyungjin Chung , Heeseong Eom , Joon Jang , Chul-Ho Sohn , Kyu Sung Choi

Alongside the growth of generative AI, we are witnessing a surge in the use of synthetic data across all stages of the AI development pipeline. It is now common practice for researchers and practitioners to use one large generative model…

Human-Computer Interaction · Computer Science 2025-05-14 Shivani Kapania , Stephanie Ballard , Alex Kessler , Jennifer Wortman Vaughan

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Many approaches have been proposed to use diffusion models to augment training datasets for downstream tasks, such as classification. However, diffusion models are themselves trained on large datasets, often with noisy annotations, and it…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Max F. Burg , Florian Wenzel , Dominik Zietlow , Max Horn , Osama Makansi , Francesco Locatello , Chris Russell

Machine learning (ML) and Artificial Intelligence (AI) have fueled remarkable advancements, particularly in healthcare. Within medical imaging, ML models hold the promise of improving disease diagnoses, treatment planning, and…

Machine Learning · Computer Science 2024-06-19 Nikolas Koutsoubis , Yasin Yilmaz , Ravi P. Ramachandran , Matthew Schabath , Ghulam Rasool

Training medical AI algorithms requires large volumes of accurately labeled datasets, which are difficult to obtain in the real world. Synthetic images generated from deep generative models can help alleviate the data scarcity problem, but…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Xiaodan Xing , Yang Nan , Federico Felder , Simon Walsh , Guang Yang

Data diversity is critical to success when training deep learning models. Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models.…

Computer Vision and Pattern Recognition · Computer Science 2018-09-17 Hoo-Chang Shin , Neil A Tenenholtz , Jameson K Rogers , Christopher G Schwarz , Matthew L Senjem , Jeffrey L Gunter , Katherine Andriole , Mark Michalski

Large-scale clinical data is invaluable to driving many computational scientific advances today. However, understandable concerns regarding patient privacy hinder the open dissemination of such data and give rise to suboptimal siloed…

Computation and Language · Computer Science 2019-05-23 Oren Melamud , Chaitanya Shivade