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Generative latent diffusion models have been established as state-of-the-art in data generation. One promising application is generation of realistic synthetic medical imaging data for open data sharing without compromising patient privacy.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Salman Ul Hassan Dar , Arman Ghanaat , Jannik Kahmann , Isabelle Ayx , Theano Papavassiliu , Stefan O. Schoenberg , Sandy Engelhardt

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

Frontier AI systems are making transformative impacts across society, but such benefits are not without costs: models trained on web-scale datasets containing personal and private data raise profound concerns about data privacy and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Sunny Duan , Mikail Khona , Abhiram Iyer , Rylan Schaeffer , Ila R Fiete

The scarcity of accessible, compliant, and ethically sourced data presents a considerable challenge to the adoption of artificial intelligence (AI) in sensitive fields like healthcare, finance, and biomedical research. Furthermore, access…

Machine Learning · Computer Science 2025-04-02 Kumar Kshitij Patel , Weitong Zhang , Lingxiao Wang

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Diffusion models were initially developed for text-to-image generation and are now being utilized to generate high quality synthetic images. Preceded by GANs, diffusion models have shown impressive results using various evaluation metrics.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Muhammad Usman Akbar , Wuhao Wang , Anders Eklund

Generally, the small size of public medical imaging datasets coupled with stringent privacy concerns, hampers the advancement of data-hungry deep learning models in medical imaging. This study addresses these challenges for 3D cardiac MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Deniz Daum , Richard Osuala , Anneliese Riess , Georgios Kaissis , Julia A. Schnabel , Maxime Di Folco

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

Large-scale text-to-image diffusion models excel in generating high-quality images from textual inputs, yet concerns arise as research indicates their tendency to memorize and replicate training data, raising We also addressed the issue of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Ruchika Chavhan , Ondrej Bohdal , Yongshuo Zong , Da Li , Timothy Hospedales

When do diffusion models reproduce their training data, and when are they able to generate samples beyond it? A practically relevant theoretical understanding of this interplay between memorization and generalization may significantly…

Machine Learning · Computer Science 2025-08-26 Sam Buchanan , Druv Pai , Yi Ma , Valentin De Bortoli

There is strong empirical evidence that the state-of-the-art diffusion modeling paradigm leads to models that memorize the training set, especially when the training set is small. Prior methods to mitigate the memorization problem often…

Machine Learning · Computer Science 2026-03-03 Kulin Shah , Alkis Kalavasis , Adam R. Klivans , Giannis Daras

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Despite their success in image generation, diffusion models can memorize training data, raising serious privacy and copyright concerns. Although prior work has sought to characterize, detect, and mitigate memorization, the fundamental…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Juyeop Kim , Songkuk Kim , Jong-Seok Lee

Diffusion-based models, such as the Stable Diffusion model, have revolutionized text-to-image synthesis with their ability to produce high-quality, high-resolution images. These advancements have prompted significant progress in image…

Cryptography and Security · Computer Science 2023-12-07 Ali Naseh , Jaechul Roh , Amir Houmansadr

As diffusion probabilistic models (DPMs) are being employed as mainstream models for generative artificial intelligence (AI), the study of their memorization of the raw training data has attracted growing attention. Existing works in this…

Cryptography and Security · Computer Science 2024-10-15 Yunhao Chen , Xingjun Ma , Difan Zou , Yu-Gang Jiang

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Diffusion models, widely used for image and video generation, face a significant limitation: the risk of memorizing and reproducing training data during inference, potentially generating unauthorized copyrighted content. While prior…

Computer Vision and Pattern Recognition · Computer Science 2025-04-28 Chen Chen , Enhuai Liu , Daochang Liu , Mubarak Shah , Chang Xu
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