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This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

The introduction of audio latent diffusion models possessing the ability to generate realistic sound clips on demand from a text description has the potential to revolutionize how we work with audio. In this work, we make an initial attempt…

Audio and Speech Processing · Electrical Eng. & Systems 2023-10-17 Dimitrios Bralios , Gordon Wichern , François G. Germain , Zexu Pan , Sameer Khurana , Chiori Hori , Jonathan Le Roux

The availability of large-scale chest X-ray datasets is a requirement for developing well-performing deep learning-based algorithms in thoracic abnormality detection and classification. However, biometric identifiers in chest radiographs…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Kai Packhäuser , Lukas Folle , Florian Thamm , Andreas Maier

Diffusion models have achieved remarkable success across a wide range of generative tasks. A key challenge is understanding the mechanisms that prevent their memorization of training data and allow generalization. In this work, we…

Machine Learning · Computer Science 2025-10-29 Tony Bonnaire , Raphaël Urfin , Giulio Biroli , Marc Mézard

Face recognition models are trained on large-scale datasets, which have privacy and ethical concerns. Lately, the use of synthetic data to complement or replace genuine data for the training of face recognition models has been proposed.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 David Geissbühler , Hatef Otroshi Shahreza , Sébastien Marcel

Machine learning has significantly advanced healthcare by aiding in disease prevention and treatment identification. However, accessing patient data can be challenging due to privacy concerns and strict regulations. Generating synthetic,…

Diffusion models, known for their tremendous ability to generate high-quality samples, have recently raised concerns due to their data memorization behavior, which poses privacy risks. Recent methods for memory mitigation have primarily…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Xiaoliu Guan , Yu Wu , Huayang Huang , Xiao Liu , Jiaxu Miao , Yi Yang

The widespread use of diffusion models has led to an abundance of AI-generated data, raising concerns about model collapse -- a phenomenon in which recursive iterations of training on synthetic data lead to performance degradation. Prior…

Machine Learning · Computer Science 2025-12-29 Lianghe Shi , Meng Wu , Huijie Zhang , Zekai Zhang , Molei Tao , Qing Qu

Diffusion models, known for their tremendous ability to generate novel and high-quality samples, have recently raised concerns due to their data memorization behavior, which poses privacy risks. Recent approaches for memory mitigation…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Xiao Liu , Xiaoliu Guan , Yu Wu , Jiaxu Miao

Generative models are increasingly used to produce privacy-preserving synthetic data as a safe alternative to sharing sensitive training datasets. However, we demonstrate that such synthetic releases can still leak information about the…

Machine Learning · Computer Science 2025-12-09 S. M. Mustaqim , Anantaa Kotal , Paul H. Yi

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Diffusion models, a powerful and universal generative AI technology, have achieved tremendous success in computer vision, audio, reinforcement learning, and computational biology. In these applications, diffusion models provide flexible…

Machine Learning · Computer Science 2024-04-12 Minshuo Chen , Song Mei , Jianqing Fan , Mengdi Wang

Deep learning in cardiac MRI (CMR) is fundamentally constrained by both data scarcity and privacy regulations. This study systematically benchmarks three generative architectures: Denoising Diffusion Probabilistic Models (DDPM), Latent…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Madhura Edirisooriya , Dasuni Kawya , Ishan Kumarasinghe , Isuri Devindi , Mary M. Maleckar , Roshan Ragel , Isuru Nawinne , Vajira Thambawita

Synthetic cardiac MRI (CMRI) generation has emerged as a promising strategy to overcome the scarcity of annotated medical imaging data. Recent advances in GANs, VAEs, diffusion probabilistic models, and flow-matching techniques aim to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Ishan Kumarasinghe , Dasuni Kawya , Madhura Edirisooriya , Isuri Devindi , Isuru Nawinne , Vajira Thambawita

Continual learning -- the ability to acquire knowledge incrementally without forgetting previous skills -- is fundamental to natural intelligence. While the human brain excels at this, artificial neural networks struggle with "catastrophic…

Machine Learning · Computer Science 2025-09-16 Aoi Otani

When deep learning models are sequentially trained on new data, they tend to abruptly lose performance on previously learned tasks, a critical failure known as catastrophic forgetting. This challenge severely limits the deployment of AI in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Paraskevi-Antonia Theofilou , Anuhya Thota , Stefanos Kollias , Mamatha Thota

Deep generative models have emerged as a transformative tool in medical imaging, offering substantial potential for synthetic data generation. However, recent empirical studies highlight a critical vulnerability: these models can memorize…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Antonio Scardace , Lemuel Puglisi , Francesco Guarnera , Sebastiano Battiato , Daniele Ravì

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

Artificial Intelligence · Computer Science 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani