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Photon-counting CT (PCCT) offers improved diagnostic performance through better spatial and energy resolution, but developing high-quality image reconstruction methods that can deal with these large datasets is challenging. Model-based…
Photon counting detectors (PCDs) offer promising advancements in computed tomography (CT) imaging by enabling the quantification and 3D imaging of contrast agents and tissue types through multi-energy projections. However, the accuracy of…
Computed Tomography (CT) is widely used in engineering and medicine for imaging the interior of objects, patients, or animals. If the employed X-ray source is monoenergetic, image reconstruction essentially means the inversion of a ray…
Model-Based Image Reconstruction (MBIR) methods significantly enhance the quality of computed tomographic (CT) reconstructions relative to analytical techniques, but are limited by high computational cost. In this paper, we propose a…
Dual-energy computed tomography (CT) is to reconstruct images of an object from two projection datasets generated from two distinct x-ray source energy spectra. It can provide more accurate attenuation quantification than conventional CT…
Multi-energy CT has long demonstrated its ability to enhance image quality with material decomposition. Yet, it has largely been limited to applications that already have high contrast. More recently, x-ray phase-contrast (XPC) imaging has…
Material decomposition refers to using the energy dependence of material physical properties to differentiate materials in a sample, which is a very important application in computed tomography(CT). In propagation-based X-ray phase-contrast…
Multi-energy computed tomography (CT) with photon counting detectors (PCDs) enables spectral imaging as PCDs can assign the incoming photons to specific energy channels. However, PCDs with many spectral channels drastically increase the…
Dual energy CT (DECT) enhances tissue characterization because it can produce images of basis materials such as soft-tissue and bone. DECT is of great interest in applications to medical imaging, security inspection and nondestructive…
X-ray computed tomography (CT) reconstructs the internal morphology of a three dimensional object from a collection of projection images, most commonly using a single rotation axis. However, for objects containing dense materials like…
X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…
Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…
In this work, we perform direct material reconstruction from spectral CT data using a model based iterative reconstruction (MBIR) approach. Material concentrations are measured in volume fractions, whose total is constrained by a maximum of…
Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…
Computed tomography (CT) is a widely used non-invasive diagnostic method in various fields, and recent advances in deep learning have led to significant progress in CT image reconstruction. However, the lack of large-scale, open-access…
Dual-energy X-ray Computed Tomography (DECT) constitutes an advanced technology which enables automatic decomposition of materials in clinical images without manual segmentation using the dependency of the X-ray linear attenuation with…
X-ray photon-counting detector (PCD) offers low noise, high resolution, and spectral characterization, representing a next generation of CT and enabling new biomedical applications. It is well known that involuntary patient motion may…
Spectral photon-counting X-ray CT (sCT) opens up new possibilities for the quantitative measurement of materials in an object, compared to conventional energy-integrating CT or dual energy CT. However, achieving reliable and accurate…
There is an increasing need to reconstruct objects in four or more dimensions corresponding to space, time and other independent parameters. The best 4D reconstruction algorithms use regularized iterative reconstruction approaches such as…
Phase-contrast X-ray imaging can improve the visibility of weakly absorbing objects (e.g. soft tissues) by an order of magnitude or more compared to conventional radiographs. Previously, it has been shown that combining phase retrieval with…