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Spectral computed tomography (CT) offers the possibility to reconstruct attenuation images at different energy levels, which can be then used for material decomposition. However, traditional methods reconstruct each energy bin individually…

In clinical CT system, the x-ray tube emits polychromatic x-rays, and the x-ray detectors operate in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral equation. However,…

Medical Physics · Physics 2020-06-23 Wenxiang Cong , Bruno De Man , Ge Wang

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies

Standard dual-energy computed tomography (CT) uses two different X-ray energies to obtain energy-dependent tissue attenuation information to allow quantitative material decomposition. The combined use of dual-energy CT and positron emission…

Medical Physics · Physics 2020-12-30 Guobao Wang

X-ray photon-counting detectors (PCDs) are drawing an increasing attention in recent years due to their low noise and energy discrimination capabilities. The energy/spectral dimension associated with PCDs potentially brings great benefits…

Medical Physics · Physics 2020-07-08 Mengzhou Li , David S. Rundle , Ge Wang

Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…

Medical Physics · Physics 2018-03-19 Wei Zhao , Don Vernekohl , Fei Han , Bin Han , Hao Peng , Lei Xing , James K Min

Modern tomography involves gathering projection data from multiple directions and feeding them into a software algorithm for tomographic reconstruction. We focus our study on image reconstruction from Radon data in the setting of…

Numerical Analysis · Mathematics 2014-12-19 Maria Angela Narduzzo

Cardiac cine magnetic resonance imaging (MRI) is one of the important means to assess cardiac functions and vascular abnormalities. Mitigating artifacts arising during image reconstruction and accelerating cardiac cine MRI acquisition to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Xiaoxiang Han , Yang Chen , Qiaohong Liu , Yiman Liu , Keyan Chen , Yuanjie Lin , Weikun Zhang

Spectral computed tomography (CT) has a great potential in material identification and decomposition. To achieve high-quality material composition images and further suppress the x-ray beam hardening artifacts, we first propose a one-step…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Weiwen Wu , Qian Wang , Fenglin Liu , Yining Zhu , Hengyong Yu

This study presents a practical and dose-efficient strategy for resolution enhancement in planar radiography, based on mechanically supersampled acquisition with high-Z photon-counting detectors (PCDs). Unlike prior event-based or cluster…

Objective. Dual-energy computed tomography (DECT) has the potential to improve contrast, reduce artifacts and the ability to perform material decomposition in advanced imaging applications. The increased number or measurements results with…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Alessandro Perelli , Suxer Alfonso Garcia , Alexandre Bousse , Jean-Pierre Tasu , Nikolaos Efthimiadis , Dimitris Visvikis

One of the advantages of spectral computed tomography (CT) is it can achieve accurate material components using the material decomposition methods. The image-based material decomposition is a common method to obtain specific material…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Weiwen Wu , Peijun Chen , Vince Vardhanabhuti , Weifei Wu , Hengyong Yu

Photon-counting computed tomography (PCCT) has emerged as a promising imaging technique, enabling spectral imaging and material decomposition (MD). However, images typically suffer from a low signal-to-noise ratio (SNR) due to constraints…

Computed tomography (CT) has been developed as a non-destructive technique for observing minute internal images of samples. It has been difficult to obtain photo-realistic (clean or clear) CT images due to various unwanted artifacts…

Quantum Physics · Physics 2023-09-12 Kyungtaek Jun

We consider the problem of signal reconstruction for computed tomography (CT) under a nonlinear forward model that accounts for exponential signal attenuation, a polychromatic X-ray source, general measurement noise (e.g., Poisson shot…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Mengqi Lou , Kabir Aladin Verchand , Sara Fridovich-Keil , Ashwin Pananjady

We introduce a new CT image reconstruction algorithm that is less affected by various artifacts. The new reconstruction algorithm is a method of minimizing the difference between synchrotron X-ray tomography data and sinograms generated…

Medical Physics · Physics 2021-11-22 Byung Chun Kim , Hyunju Lee , Kyungtaek Jun

Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

Multi-material decomposition (MMD) enables quantitative reconstruction of tissue compositions in the human body, supporting a wide range of clinical applications. However, traditional MMD typically requires spectral CT scanners and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Qing Wu , Hongjiang Wei , Jingyi Yu , S. Kevin Zhou , Yuyao Zhang

Photon counting CT (PCCT) has been a research focus in the last two decades. Recent studies and advancements have demonstrated that systems using semiconductor-based photon counting detectors (PCDs) have the potential to provide better…

CT imaging works by reconstructing an object of interest from a collection of projections. Traditional methods such as filtered-back projection (FBP) work on projection images acquired around a fixed rotation axis. However, for some CT…

Image and Video Processing · Electrical Eng. & Systems 2022-09-19 Diyu Yang , Craig A. J. Kemp , Gregery T. Buzzard , Charles A. Bouman