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The spatial structure of the cell is highly organized at all levels: from small complexes and assemblies, to local nano- and micro-clusters, to global, micrometer scales across and between cells. We suggest that this multiscale spatial cell…

Biomolecules · Quantitative Biology 2013-08-06 Ruth Nussinov

Understanding of the molecular interaction between asphaltenes and other molecules, which may act as its solvents, provides insights into the nature of its stability in petroleum fluids and its phase transitions. Molecular dynamics…

Chemical Physics · Physics 2019-07-04 Salah Yaseen , G. Ali Mansoori

Filament formation by non-cytoskeletal enzymes has been known for decades, yet only relatively recently has its wide-spread role in enzyme regulation and biology come to be appreciated. This comprehensive review summarizes what is known for…

Biomolecules · Quantitative Biology 2019-10-01 Chad K. Park , Nancy C. Horton

In this paper we propose an existence and uniqueness theory for the solutions of a system of non-linear hyperbolic conservation laws, structured in age and maturity variables, representing a tissue environment. In particular we are…

Analysis of PDEs · Mathematics 2014-08-22 Di Bernardo Laura , Donatella Donatelli

=One of the most frequently farmed crops is the tomato crop. Late blight is the most prevalent tomato disease in the world, and often causes a significant reduction in the production of tomato crops. The importance of tomatoes as an…

Computer Vision and Pattern Recognition · Computer Science 2023-06-12 Muhammad Shoaib Farooq , Tabir Arif , Shamyla Riaz

Non-invasive light scattering methods provide data on biological macromolecules (i.e. proteins, nucleic acids, as well as assemblies and larger entities composed of them) that are complementary with those of size exclusion chromatography,…

Biomolecules · Quantitative Biology 2018-10-02 Bernard Lorber

Self-supervised representation learning (SSL) on biomedical networks provides new opportunities for drug discovery. However, how to effectively combine multiple SSL models is still challenging and has been rarely explored. Therefore, we…

Machine Learning · Computer Science 2022-12-20 Xiaoqi Wang , Yingjie Cheng , Yaning Yang , Yue Yu , Fei Li , Shaoliang Peng

State-space models (SSMs) are an important modeling framework for analyzing ecological time series. These hierarchical models are commonly used to model population dynamics, animal movement, and capture-recapture data, and are now…

Soil is a complex, dynamic material, with physical properties that depend on its biological content. We propose a cellular automaton model for self-organizing soil structure, where soil aggregates and serves as food for microbial species.…

Biological Physics · Physics 2025-10-10 Riz Fernando Noronha , Kim Sneppen , Kunihiko Kaneko

Photosynthetic eukaryotes show a remarkable variability in photosynthesis, including large differences in light harvesting proteins and pigment composition. In vivo circular spectropolarimetry enables us to probe the molecular architecture…

Biomolecules · Quantitative Biology 2018-08-27 C. H. Lucas Patty , Freek Ariese , Wybren Jan Buma , Inge Loes ten Kate , Rob J. M. van Spanning , Frans Snik

Recent advances in metagenomics have revealed macroecological patterns or "laws" describing robust statistical regularities across microbial communities. Stochastic logistic models (SLMs), which treat species as independent -- akin to ideal…

Populations and Evolution · Quantitative Biology 2026-02-02 Rubén Calvo , Adrián Roig , Roberto Corral López , José Camacho-Mateu , José A. Cuesta , Miguel A. Muñoz

We describe a system of stochastic differential equations (SDEs) which model the interaction between processive molecular motors, such as kinesin and dynein, and the biomolecular cargo they tow as part of microtubule-based intracellular…

Probability · Mathematics 2011-11-04 Scott A. McKinley , Avanti Athreya , John Fricks , Peter R. Kramer

Time-series data can represent the behaviors of autonomous systems, such as drones and self-driving cars. The task of binary and multi-class classification for time-series data has become a prominent area of research. Neural networks…

Machine Learning · Statistics 2024-06-26 Danyang Li , Roberto Tron

Allostery is a fundamental property of proteins that represents the functional coupling between distantly located sites. In different manifestations, this property underlies signal transduction, gene expression, and regulation -- elementary…

Biomolecules · Quantitative Biology 2024-11-14 Eric Rouviere , Olivier Rivoire , Rama Ranganathan

Designing synthetic routes for novel molecules is pivotal in various fields like medicine and chemistry. In this process, researchers need to explore a set of synthetic reactions to transform starting molecules into intermediates step by…

Human-Computer Interaction · Computer Science 2025-03-18 Qipeng Wang , Rui Sheng , Shaolun Ruan , Xiaofu Jin , Chuhan Shi , Min Zhu

Plants synthesize volatile organic compounds (VOCs) to attract pollinators and beneficial microorganisms, to defend themselves against herbivores and pathogens and for plant-plant communication. Generally, accumulation and emission of VOCs…

Traffic-like collective movements are observed at almost all levels of biological systems. Molecular motor proteins like, for example, kinesin and dynein, which are the vehicles of almost all intra-cellular transport in eukayotic cells,…

Biological Physics · Physics 2008-01-16 Debashish Chowdhury , Andreas Schadschneider , Katsuhiro Nishinari

In an effort to understand ``rafts'' in biological membranes, we propose phenomenological models for saturated and unsaturated lipid mixtures, and lipid-cholesterol mixtures. We consider simple couplings between the local composition and…

Soft Condensed Matter · Physics 2009-11-10 Shigeyuki Komura , Hisashi Shirotori , Peter D. Olmsted , David Andelman

Proteins synthesized on membrane-bound ribosomes are sorted at the Golgi apparatus level for delivery to various cellular destinations: the plasma membrane or the extracellular space, and the lytic vacuole or lysosome. Sorting involves the…

Genomics · Quantitative Biology 2007-05-23 F. G. Masclaux , J. -P. Galaud , R. Pont-Lezica

Various theoretical studies have been carried out to infer relevant protein-protein interactions among pathogens and their hosts. Such studies are generally based on preferential attachment of bacteria / virus to their human receptor…

Molecular Networks · Quantitative Biology 2019-07-09 S. Chatterjee , B. S. Sanjeev
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