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Understanding the structure of a protein complex is crucial indetermining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are two-dimensional.…

Quantitative Methods · Quantitative Biology 2021-10-18 Benjamin J. Blundell , Christian Sieben , Suliana Manley , Ed Rosten , QueeLim Ch'ng , Susan Cox

The neuroimaging technique three-dimensional polarized light imaging (3D-PLI) provides a high-resolution reconstruction of nerve fibres in human post-mortem brains. The orientations of the fibres are derived from birefringence measurements…

Medical Physics · Physics 2015-10-12 Miriam Menzel , Kristel Michielsen , Hans De Raedt , Julia Reckfort , Katrin Amunts , Markus Axer

This study investigates a 3D and fully convolutional neural network (CNN) for subcortical brain structure segmentation in MRI. 3D CNN architectures have been generally avoided due to their computational and memory requirements during…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 J. Dolz , C. Desrosiers , I. Ben Ayed

Recently, self-supervised learning (SSL) methods have been used in pre-training the segmentation models for 2D and 3D medical images. Most of these methods are based on reconstruction, contrastive learning and consistency regularization.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Haofeng Li , Yiming Ouyang , Xiang Wan

While self-supervised learning has been shown to benefit a number of vision tasks, existing techniques mainly focus on image-level manipulation, which may not generalize well to downstream tasks at patch or pixel levels. Moreover, existing…

Computer Vision and Pattern Recognition · Computer Science 2022-08-31 Cheng-Yen Hsieh , Chih-Jung Chang , Fu-En Yang , Yu-Chiang Frank Wang

Traditional supervised learning with deep neural networks requires a tremendous amount of labelled data to converge to a good solution. For 3D medical images, it is often impractical to build a large homogeneous annotated dataset for a…

Self-supervised learning methods have witnessed a recent surge of interest after proving successful in multiple application fields. In this work, we leverage these techniques, and we propose 3D versions for five different self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Aiham Taleb , Winfried Loetzsch , Noel Danz , Julius Severin , Thomas Gaertner , Benjamin Bergner , Christoph Lippert

Contrastive self-supervised learning based on point-wise comparisons has been widely studied for vision tasks. In the visual cortex of the brain, neuronal responses to distinct stimulus classes are organized into geometric structures known…

Machine Learning · Computer Science 2026-01-06 Guanming Zhang , David J. Heeger , Stefano Martiniani

Current state-of-the-art methods cast monocular 3D human pose estimation as a learning problem by training neural networks on large data sets of images and corresponding skeleton poses. In contrast, we propose an approach that can exploit…

Computer Vision and Pattern Recognition · Computer Science 2020-10-14 Simon Jenni , Paolo Favaro

Cytoarchitectonic parcellations of the human brain serve as anatomical references in multimodal atlas frameworks. They are based on analysis of cell-body stained histological sections and the identification of borders between brain areas.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Hannah Spitzer , Kai Kiwitz , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

Diffusion-weighted magnetic resonance imaging (DW-MRI) allows for non-invasive imaging of the local fiber architecture of the human brain at a millimetric scale. Multiple classical approaches have been proposed to detect both single (e.g.,…

The goal of self-supervised visual representation learning is to learn strong, transferable image representations, with the majority of research focusing on object or scene level. On the other hand, representation learning at part level has…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Subhabrata Choudhury , Iro Laina , Christian Rupprecht , Andrea Vedaldi

Self-supervised learning is showing great promise for monocular depth estimation, using geometry as the only source of supervision. Depth networks are indeed capable of learning representations that relate visual appearance to 3D properties…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Vitor Guizilini , Rui Hou , Jie Li , Rares Ambrus , Adrien Gaidon

Inspired by biology's most sophisticated computer, the brain, neural networks constitute a profound reformulation of computational principles. Remarkably, analogous high-dimensional, highly-interconnected computational architectures also…

Disordered Systems and Neural Networks · Physics 2024-01-23 Constantine Glen Evans , Jackson O'Brien , Erik Winfree , Arvind Murugan

Protein-ligand scoring is an important step in a structure-based drug design pipeline. Selecting a correct binding pose and predicting the binding affinity of a protein-ligand complex enables effective virtual screening. Machine learning…

Machine Learning · Statistics 2020-10-19 Joshua Hochuli , Alec Helbling , Tamar Skaist , Matthew Ragoza , David Ryan Koes

Accurate local fiber orientation distribution (FOD) modeling based on diffusion magnetic resonance imaging (dMRI) capable of resolving complex fiber configurations benefits from specific acquisition protocols that sample a high number of…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Oeslle Lucena , Sjoerd B. Vos , Vejay Vakharia , John Duncan , Keyoumars Ashkan , Rachel Sparks , Sebastien Ourselin

This paper strives for self-supervised learning of a feature space suitable for skeleton-based action recognition. Our proposal is built upon learning invariances to input skeleton representations and various skeleton augmentations via a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Fida Mohammad Thoker , Hazel Doughty , Cees G. M. Snoek

Deep learning shows high potential for many medical image analysis tasks. Neural networks can work with full-size data without extensive preprocessing and feature generation and, thus, information loss. Recent work has shown that the…

Although recent advancements in end-to-end learning-based link prediction (LP) methods have shown remarkable capabilities, the significance of traditional similarity-based LP methods persists in unsupervised scenarios where there are no…

Artificial Intelligence · Computer Science 2024-10-28 Chenhan Zhang , Weiqi Wang , Zhiyi Tian , James Jianqiao Yu , Mohamed Ali Kaafar , An Liu , Shui Yu

Cytoarchitectonic maps provide microstructural reference parcellations of the brain, describing its organization in terms of the spatial arrangement of neuronal cell bodies as measured from histological tissue sections. Recent work provided…

Image and Video Processing · Electrical Eng. & Systems 2021-06-02 Christian Schiffer , Katrin Amunts , Stefan Harmeling , Timo Dickscheid