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The surface tension of living cells and tissues originates from the generation of nonequilibrium active stresses within the cell cytoskeleton. Here, using laser ablation, we generate gradients in the surface tension of cellular aggregates…

We study elasticity-driven morphological transitions of soft spherical core shell structures in which the core can be treated as an isotropic elastic continuum and the surface or shell as a tensionless liquid layer, whose elastic response…

Soft Condensed Matter · Physics 2013-11-13 Craig Fogle , Amy C. Rowat , Alex J. Levine , Joseph Rudnick

We consider a cylinder immersed in viscous fluid moving near a flat substrate covered by an incompressible viscoelastic fluid layer, and study the effect of the fluid viscoelasticity on the lift force exerted on the cylinder. The lift force…

Fluid Dynamics · Physics 2023-08-22 Shiyuan Hu , Fanlong Meng , Masao Doi

Fluid stretching in porous media governs the mixing of reactants, contaminants, and nutrients, yet how the solid microstructure controls the stretching statistics remains poorly understood. We investigate how porous-medium heterogeneity…

Fluid Dynamics · Physics 2026-04-06 J. Kevin Pierce , Tanguy Le Borgne , Francois Renard , Gaute Linga

The origin of rigidity in disordered materials is an outstanding open problem in statistical physics. Previously, a class of 2D cellular models has been shown to undergo a rigidity transition controlled by a mechanical parameter that…

Soft Condensed Matter · Physics 2023-01-18 Matthias Merkel , Lisa Manning

Repeated loading of a solid leads to microstructural damage that ultimately results in catastrophic material failure. While posing a major threat to the stability of virtually all materials, the microscopic origins of fatigue, especially…

Soft Condensed Matter · Physics 2018-05-23 Jan Maarten van Doorn , Joanne E. Verweij , Joris Sprakel , Jasper van der Gucht

The dynamics of a stiff filament (made by connecting beads) embedded in size-polydisperse hard sphere fluid is investigated by means of molecular dynamics simulations with focus on how the degree of size-polydispersity, characterized by…

Soft Condensed Matter · Physics 2025-03-06 Thokchom Premkumar Meitei , Lenin S. Shagolsem

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

Biological Physics · Physics 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

To understand how the mechanical properties of tissues emerge from interactions of multiple cells, we measure traction stresses of cohesive colonies of 1-27 cells adherent to soft substrates. We find that traction stresses are generally…

Tissue fusion eliminates physical voids in a tissue to form a continuous structure and is central to many processes in development and repair. Fusion events in vivo, particularly in embryonic development, often involve the purse-string…

Tissues and Organs · Quantitative Biology 2015-08-12 V. Nier , M. Deforet , G. Duclos , H. G. Yevick , O. Cochet-Escartin , P. Marcq , P. Silberzan

Cilia and flagella are hair-like appendages that protrude from the surface of a variety of eukaryotic cells and deform in a wavelike fashion to transport fluids and propel cells. Motivated by the ubiquity of non-Newtonian fluids in biology,…

Fluid Dynamics · Physics 2014-03-19 J. Rodrigo Vélez-Cordero , Eric Lauga

We performed dynamic pressure buckling experiments on defect-seeded spherical shells made of a common silicone elastomer. Unlike in quasi-static experiments, shells buckled at ostensibly subcritical pressures (i.e. below the…

Soft Condensed Matter · Physics 2021-10-04 Lucia Stein-Montalvo , Douglas P. Holmes , Gwennou Coupier

Mechanobiology is gaining more and more traction as the fundamental role of physical forces in biological function becomes clearer. Forces at the microscale are often measured indirectly using inverse problems such as Traction Force…

Biological Physics · Physics 2025-03-21 Aleix Boquet-Pujadas

Contacts between particles in dense, sheared suspensions are believed to underpin much of their rheology. Roughness and adhesion are known to constrain the relative motion of particles, and thus globally affect the shear response, but an…

Light forces induced by scattering and absorption in elastic dielectrics lead to local density modulations and deformations. These perturbations in turn modify light propagation in the medium and generate an intricate nonlinear response. We…

Optics · Physics 2012-11-01 Matthias Sonnleitner , Monika Ritsch-Marte , Helmut Ritsch

In this paper, we study how cytoskeletal remodeling is correlated to changes in subcellular microrheology. We analyze the changes in the magnitude and directionality of the shear and elastic moduli of bovine aortic endothelial cells (BAECs)…

Quantitative Methods · Quantitative Biology 2013-09-12 Kathryn Osterday , Thomas Chew , Phillip Loury , Jason Haga , Manuel Gomez-Gonzalez , Juan C. del Alamo , Shu Chien

Cell membrane tension directly influences various cellular functions. In this study, we developed a method to estimate surface tension from time-series data. We obtained the curvature-velocity relationship from time-series of binarized cell…

Cell Behavior · Quantitative Biology 2025-04-22 Hiroki Nishitani , Takashi Miura

A thin, elastic sheet floating on the surface of a liquid bath wrinkles when poked at its centre. We study the onset of wrinkling as well as the evolution of the pattern as indentation progresses far beyond the wrinkling threshold. We use…

Soft Condensed Matter · Physics 2018-07-31 Dominic Vella , Benny Davidovitch

We studied regenerating bilayered tissue toroids dissected from Hydra vulgaris polyps and relate our macroscopic observations to the dynamics of force-generating mesoscopic cytoskeletal structures. Tissue fragments undergo a specific…

This paper deals with flow-induced shape transitions of elastic capsules. The state of the art concerning both theory and experiments is briefly reviewed starting with dynamically induced small deformation of initially spherical capsules…

Soft Condensed Matter · Physics 2011-04-25 Reimar Finken , Steffen Kessler , Udo Seifert
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