Viscoelastic Properties of Vascular Endothelial Cells Exposed to Stretch
Quantitative Methods
2013-09-12 v1 Soft Condensed Matter
Biological Physics
Cell Behavior
Abstract
In this paper, we study how cytoskeletal remodeling is correlated to changes in subcellular microrheology. We analyze the changes in the magnitude and directionality of the shear and elastic moduli of bovine aortic endothelial cells (BAECs) exposed to cyclical, uniaxial stretch. We find that, when stretched, BAECs stiffen and align their softest direction of mechanical polarization perpendicular to stretch. We hypothesize that the response of VECs to stretch acts to minimize intracellular strain in response to stress.
Keywords
Cite
@article{arxiv.1309.2683,
title = {Viscoelastic Properties of Vascular Endothelial Cells Exposed to Stretch},
author = {Kathryn Osterday and Thomas Chew and Phillip Loury and Jason Haga and Manuel Gomez-Gonzalez and Juan C. del Alamo and Shu Chien},
journal= {arXiv preprint arXiv:1309.2683},
year = {2013}
}
Comments
XXIII ICTAM Conference Paper, 2012