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In recent years, a few multiple-resolution modelling strategies have been proposed, in which functionally relevant parts of a biomolecule are described with atomistic resolution, while the remainder of the system is concurrently treated…

Soft Condensed Matter · Physics 2023-01-20 Raffaele Fiorentini , Thomas Tarenzi , Raffaello Potestio

Multimodal approaches that integrate protein structure and sequence have achieved remarkable success in protein-protein interface prediction. However, extending these methods to protein-peptide interactions remains challenging due to the…

Signal Processing · Electrical Eng. & Systems 2025-11-03 Dian Chen , Yunkai Chen , Tong Lin , Sijie Chen , Xiaolin Cheng

Code completion has become an essential tool for daily software development. Existing evaluation benchmarks often employ static methods that do not fully capture the dynamic nature of real-world coding environments and face significant…

Computation and Language · Computer Science 2024-12-17 Jian Yang , Jiajun Zhang , Jiaxi Yang , Ke Jin , Lei Zhang , Qiyao Peng , Ken Deng , Yibo Miao , Tianyu Liu , Zeyu Cui , Binyuan Hui , Junyang Lin

Coarse-graining (CG) reduces molecular details to extend the time and length scales of molecular dynamics simulations to microseconds and micrometers. However, the CG approaches have long been limited by the difficulty of constructing both…

Chemical Physics · Physics 2026-05-06 Kevin V. Bigting , Shubhadeep Nag , Yaxin An

In recent years, promising deep learning based interatomic potential energy surface (PES) models have been proposed that can potentially allow us to perform molecular dynamics simulations for large scale systems with quantum accuracy.…

Computational Physics · Physics 2020-06-23 Yuzhi Zhang , Haidi Wang , Weijie Chen , Jinzhe Zeng , Linfeng Zhang , Han Wang , Weinan E

Polymer-Attenuated Coulombic Self-Assembly (PACS) is a flexible experimental approach for generating crystals from simple colloidal building blocks. The central components are charged spherical particles coated with a polymer brush that…

Exascale computing delivers the raw power to simulate ever larger and more chemically realistic systems, but realizing this potential requires codes that can efficiently use thousands of processors. Our real-space multigrid (RMG) density…

Materials Science · Physics 2026-01-19 R. J. Morelock , S. Bagchi , E. L. Briggs , W. Lu , J. Bernholc , P. Ganesh

High-quality data is essential for modern machine learning, yet many valuable corpora are sensitive and cannot be freely shared. Synthetic data offers a practical substitute for downstream development, and large language models (LLMs) have…

Computation and Language · Computer Science 2026-02-26 Amin Banayeeanzade , Qingchuan Yang , Deqing Fu , Spencer Hong , Erin Babinsky , Alfy Samuel , Anoop Kumar , Robin Jia , Sai Praneeth Karimireddy

This article presents an open-source Python package for simulating micro-thermoelectric generators, based on the work by D. Beretta et al. (Sustainable Energy Fuels, 2017). Featuring a user-friendly graphical user interface and robust…

Mesoscale and Nanoscale Physics · Physics 2025-10-21 D. Beretta

ixpeobssim is a simulation and analysis framework, based on the Python programming language and the associated scientific ecosystem, specifically developed for the Imaging X-ray Polarimetry Explorer (IXPE). Given a source model and the…

Instrumentation and Methods for Astrophysics · Physics 2022-09-23 L. Baldini , N. Bucciantini , N. Di Lalla , S. R. Ehlert , A. Manfreda , M. Negro , N. Omodei , M. Pesce-Rollins , C. Sgrò , S. Silvestri

Peppytides is a coarse-grained, accurate, physical model of the polypeptide chain. I have shared instructions to make your own polypeptide chain and STL files of Peppytides in MAKE magazine in Jan 2014 issue. However, Peppytides involves a…

Other Quantitative Biology · Quantitative Biology 2016-05-16 Promita Chakraborty

GMP-Featurizer is a lightweight, accurate, efficient, and scalable software package for calculating the Gaussian Multipole (GMP) features \cite{GMP} for a variety of atomic systems with elements across the periodic table. Starting from the…

Chemical Physics · Physics 2023-03-24 Xiangyun Lei , Joseph Montoya

Electroencephalography (EEG)-based Brain-Computer Interfaces (BCIs) have emerged as a transformative technology with applications spanning robotics, virtual reality, medicine, and rehabilitation. However, existing BCI frameworks face…

Signal Processing · Electrical Eng. & Systems 2025-10-13 Gursimran Singh , Aviral Chharia , Rahul Upadhyay , Vinay Kumar , Luca Longo

We present the CALVADOS package for performing simulations of biomolecules using OpenMM and the coarse-grained CALVADOS model. The package makes it easy to run simulations using the family of CALVADOS models of biomolecules including…

Process Execution Engines are a vital part of Business Process Management (BPM) and Manufacturing Orchestration Management (MOM), as they allow the business or manufacturing logic (expressed in a graphical notation such as BPMN) to be…

Other Computer Science · Computer Science 2022-09-20 Juergen Mangler , Stefanie Rinderle-Ma

The Simulation Environment for Atomistic and Molecular Modeling (SEAMM) is an open-source software package written in Python that provides a graphical interface for setting up, executing, and analyzing molecular and materials simulations.…

Liquid chromatography-mass spectrometry (LC-MS/MS) data analysis requires adaptable software solutions to meet diverse analytical needs. We present eMZed 3, a modern Python framework for flexible and interactive analysis of LC-MS/MS data.…

Quantitative Methods · Quantitative Biology 2026-05-28 Uwe Schmitt , Jethro L. Hemmann , Nicola Zamboni , Julia A. Vorholt , Patrick Kiefer

ControlBurn is a Python package to construct feature-sparse tree ensembles that support nonlinear feature selection and interpretable machine learning. The algorithms in this package first build large tree ensembles that prioritize basis…

Machine Learning · Statistics 2022-07-11 Brian Liu , Miaolan Xie , Haoyue Yang , Madeleine Udell

We present ForSE (Foreground Scale Extender), a novel Python package which aims at overcoming the current limitations in the simulation of diffuse Galactic radiation, in the context of Cosmic Microwave Background experiments (CMB). ForSE…

Cosmology and Nongalactic Astrophysics · Physics 2021-05-03 Nicoletta Krachmalnicoff , Giuseppe Puglisi

Research into the processes of photoionised nebulae plays a significant part in our understanding of stellar evolution. It is extremely difficult to visually represent or model ionised nebula, requiring astronomers to employ sophisticated…

Instrumentation and Methods for Astrophysics · Physics 2020-05-26 K. Fitzgerald , E. J Harvey , N. Keaveney , M. Redman