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SHallow REcurrent Decoders (SHRED) provide a deep learning strategy for modeling high-dimensional dynamical systems and/or spatiotemporal data from dynamical system snapshot observations. PySHRED is a Python package that implements SHRED…

Machine Learning · Computer Science 2025-07-29 David Ye , Jan Williams , Mars Gao , Stefano Riva , Matteo Tomasetto , David Zoro , J. Nathan Kutz

Large-scale modelling of three-dimensional controlled-source electromagnetic (CSEM) surveys used to be feasible only for large companies and research consortia. This has changed over the last few years, and today there exists a selection of…

Probabilistic Circuits (PCs) are a general framework for tractable deep generative models, which support exact and efficient probabilistic inference on their learned distributions. Recent modeling and training advancements have enabled…

Machine Learning · Computer Science 2025-11-03 Anji Liu , Kareem Ahmed , Guy Van den Broeck

The popularity of Bayesian statistical methods has increased dramatically in recent years across many research areas and industrial applications. This is the result of a variety of methodological advances with faster and cheaper hardware as…

Computation · Statistics 2022-01-12 Tomás Capretto , Camen Piho , Ravin Kumar , Jacob Westfall , Tal Yarkoni , Osvaldo A. Martin

Machine learning potentials are an important tool for molecular simulation, but their development is held back by a shortage of high quality datasets to train them on. We describe the SPICE dataset, a new quantum chemistry dataset for…

We present PyMoosh, a Python-based simulation library designed to provide a comprehensive set of numerical tools allowing to compute essentially all optical characteristics of multilayered structures, ranging from reflectance and…

A new molecular simulation toolkit composed of some lately developed force fields and specified models is presented to study the self-assembly, phase transition, and other properties of polymeric systems at mesoscopic scale by utilizing the…

Computational Physics · Physics 2013-10-10 You-Liang Zhu , Hong Liu , Zhan-Wei Li , Hu-Jun Qian , Giuseppe Milano , Zhong-Yuan Lu

Protein engineering is important for biomedical applications, but conventional approaches are often inefficient and resource-intensive. While deep learning (DL) models have shown promise, their training or implementation into protein…

Quantitative Methods · Quantitative Biology 2024-11-08 Yungeng Liu , Zan Chen , Yu Guang Wang , Yiqing Shen

We present GP-MOBO, a novel multi-objective Bayesian Optimization algorithm that advances the state-of-the-art in molecular optimization. Our approach integrates a fast minimal package for Exact Gaussian Processes (GPs) capable of…

Machine Learning · Computer Science 2025-08-21 Anabel Yong

We introduce CRPE (Code Reasoning Process Enhancer), an innovative three-stage framework for data synthesis and model training that advances the development of sophisticated code reasoning capabilities in large language models (LLMs).…

Software Engineering · Computer Science 2025-05-19 Ningxin Gui , Qianghuai Jia , Feijun Jiang , Yuling Jiao , dechun wang , Jerry Zhijian Yang

Credibility building activities in computational research include verification and validation, reproducibility and replication, and uncertainty quantification. Though orthogonal to each other, they are related. This paper presents…

Computational Physics · Physics 2021-04-28 Natalia C. Clementi , Lorena A. Barba

ipie is a Python-based auxiliary-field quantum Monte Carlo (AFQMC) package that has undergone substantial improvements since its initial release [J. Chem. Theory Comput., 2023, 19(1): 109-121]. This paper outlines the improved modularity…

Designing enzyme backbones with substrate-specific functionality is a critical challenge in computational protein engineering. Current generative models excel in protein design but face limitations in binding data, substrate-specific…

Biomolecules · Quantitative Biology 2025-10-30 Chao Song , Zhiyuan Liu , Han Huang , Liang Wang , Qiong Wang , Jianyu Shi , Hui Yu , Yihang Zhou , Yang Zhang

The development of spiking neural network simulation software is a critical component enabling the modeling of neural systems and the development of biologically inspired algorithms. Existing software frameworks support a wide range of…

Neural and Evolutionary Computing · Computer Science 2019-03-27 Hananel Hazan , Daniel J. Saunders , Hassaan Khan , Darpan T. Sanghavi , Hava T. Siegelmann , Robert Kozma

Physics-informed machine learning (PIML) has emerged as a promising alternative to conventional numerical methods for solving partial differential equations (PDEs). PIML models are increasingly built via deep neural networks (NNs) whose…

Machine Learning · Computer Science 2024-09-30 Carlos Mora , Amin Yousefpour , Shirin Hosseinmardi , Ramin Bostanabad

We describe a simple and efficient Python code to perform Bayesian forecasting for gravitational waves (GW) produced by Extreme-Mass-Ratio-Inspiral systems (EMRIs). The code runs on GPUs for an efficient parallelised computation of…

General Relativity and Quantum Cosmology · Physics 2025-01-22 Ippocratis D. Saltas , Roberto Oliveri

As wide-field surveys yield ever more precise measurements, cosmology has entered a phase of high precision requiring highly accurate and fast theoretical predictions. At the heart of most cosmological model predictions is a numerical…

Cosmology and Nongalactic Astrophysics · Physics 2017-08-18 Alexandre Refregier , Lukas Gamper , Adam Amara , Lavinia Heisenberg

Component-Based Software Engineering (CBSE) is a methodology that assembles pre-existing, re-usable software components into new applications, which is particularly relevant for fast moving, data-intensive fields such as bioinformatics.…

Mathematical Software · Computer Science 2024-06-18 Christos Argyropoulos

For several decades, the CPU has been the standard model to use in the majority of computing. While the CPU does excel in some areas, heterogeneous computing, such as reconfigurable hardware, is showing increasing potential in areas like…

Hardware Architecture · Computer Science 2021-04-21 Carl-Johannes Johnsen , Alberte Thegler , Kenneth Skovhede , Brian Vinter

Monte Carlo (MC) methods are important computational tools for molecular structure optimizations and predictions. When solvent effects are explicitly considered, MC methods become very expensive due to the large degree of freedom associated…

Biomolecules · Quantitative Biology 2022-02-09 Jiahui Chen , Weihua Geng , Guo-Wei Wei
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