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Predicting protein complex structures is essential for protein function analysis, protein design, and drug discovery. While AI methods like AlphaFold can predict accurate structural models for many protein complexes, reliably estimating the…

Biomolecules · Quantitative Biology 2025-05-30 Pawan Neupane , Jian Liu , Jianlin Cheng

We have developed PyTIE (Python Topological Indices Expressions) which is defined as the collections of Python packages such as PyTIE D, PyTIE DS, PyTIE SMS DE, and PyTIE SMS DSE, which are open-source software packages and cross-platform…

Chemical Physics · Physics 2025-11-03 Sahaya Vijay Jeyaraj , Roy S , Govardhan S , Tony Augustine , Jyothish K

We develop an open-source python workflow package, $py$GWBSE to perform automated first-principles calculations within the GW-BSE (Bethe-Salpeter) framework. GW-BSE is a many body perturbation theory based approach to explore the…

Materials Science · Physics 2022-10-06 Tathagata Biswas , Arunima K. Singh

PySDM is an open-source Python package for simulating the dynamics of particles undergoing condensational and collisional growth, interacting with a fluid flow and subject to chemical composition changes. It is intended to serve as a…

There is a need for open-source libraries in emission tomography that (i) use modern and popular backend code to encourage community contributions and (ii) offer support for the multitude of reconstruction techniques available in recent…

Automated molecular simulations are used extensively for predicting material properties. Typically, these simulations exhibit two regimes: a dynamic equilibration part, followed by a steady state. For extracting observable properties, the…

Mesoscale and Nanoscale Physics · Physics 2024-09-20 Felipe Lopes Oliveira , Binquan Luan , Pierre Mothé Esteves , Mathias Steiner , Rodrigo Neumann Barros Ferreira

We present a new software pipeline -- PyMorph -- for automated estimation of structural parameters of galaxies. Both parametric fits through a two dimensional bulge disk decomposition as well as structural parameter measurements like…

Instrumentation and Methods for Astrophysics · Physics 2015-05-19 Vinu Vikram , Yogesh Wadadekar , Ajit K. Kembhavi , G. V. Vijayagovindan

Computed tomography perfusion (CTP) and magnetic resonance perfusion (MRP) are widely used in acute ischemic stroke assessment and other cerebrovascular conditions to generate quantitative maps of cerebral hemodynamics. While commercial…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Marijn Borghouts , Ruisheng Su

Developing complex biomolecular workflows is not always straightforward. It requires tedious developments to enable the interoperability between the different biomolecular simulation and analysis tools. Moreover, the need to execute the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-12-20 Jorge Ejarque , Pau Andrio , Adam Hospital , Javier Conejero , Daniele Lezzi , Josep LL. Gelpi , Rosa M. Badia

Computational experiments using spatial stochastic simulations have led to important new biological insights, but they require specialized tools, a complex software stack, as well as large and scalable compute and data analysis resources…

Computational Engineering, Finance, and Science · Computer Science 2015-08-17 Brian Drawert , Michael Trogdon , Salman Toor , Linda Petzold , Andreas Hellander

This paper is a guide to the installation and use of the Python package PYESSENCE. PYESSENCE is designed to evolve linear perturbations to Coupled Quintessence models with a arbitrary number of cold dark matter (CDM) fluids and dark energy…

Cosmology and Nongalactic Astrophysics · Physics 2016-08-10 Alexander Leithes

Unmodelled searches and reconstruction is a critical aspect of gravitational wave data analysis, requiring sophisticated software tools for robust data analysis. This paper introduces PycWB, a user-friendly and modular Python-based…

General Relativity and Quantum Cosmology · Physics 2024-03-05 Yumeng Xu , Shubhanshu Tiwari , Marco Drago

We present PyCCE, an open-source Python library to simulate the dynamics of spin qubits in a spin bath, using the cluster-correlation expansion (CCE) method. PyCCE includes modules to generate realistic spin baths, employing coupling…

Quantum Physics · Physics 2021-07-14 Mykyta Onizhuk , Giulia Galli

Electrostatic interactions play crucial roles in biophysical processes such as protein folding and molecular recognition. Poisson-Boltzmann equation (PBE)-based models have emerged as widely used in modeling these important processes.…

Computational Physics · Physics 2017-04-11 Ruxi Qi , Wesley M. Botello-Smith , Ray Luo

Programming by example (PBE) is an emerging programming paradigm that automatically synthesizes programs specified by user-provided input-output examples. Despite the convenience for end-users, implementing PBE tools often requires strong…

Software Engineering · Computer Science 2023-07-25 Jiarong Wu , Lili Wei , Yanyan Jiang , Shing-Chi Cheung , Luyao Ren , Chang Xu

We present ChemXploreML, a modular desktop application designed for machine learning-based molecular property prediction. The framework's flexible architecture allows integration of any molecular embedding technique with modern machine…

Chemical Physics · Physics 2025-05-14 Aravindh Nivas Marimuthu , Brett A. McGuire

Sparse linear algebra is a cornerstone of many scientific computing and machine learning applications. Python has become a popular choice for these applications due to its simplicity and ease of use. Yet high performance sparse kernels in…

Mathematical Software · Computer Science 2025-10-10 Keshvi Tuteja , Gregor Olenik , Roman Mishchuk , Yu-Hsiang Tsai , Markus Götz , Achim Streit , Hartwig Anzt , Charlotte Debus

Peptide self-assembly prediction offers a powerful bottom-up strategy for designing biocompatible, low-toxicity materials for large-scale synthesis in a broad range of biomedical and energy applications. However, screening the vast sequence…

Biomolecules · Quantitative Biology 2026-04-23 Nuno Costa , Julija Zavadlav

FCMpy is an open source package in Python for building and analyzing Fuzzy Cognitive Maps. More specifically, the package allows 1) deriving fuzzy causal weights from qualitative data, 2) simulating the system behavior, 3) applying machine…

Mathematical Software · Computer Science 2022-11-03 Samvel Mkhitaryan , Philippe J. Giabbanelli , Maciej K. Wozniak , Gonzalo Napoles , Nanne K. de Vries , Rik Crutzen

In this paper, we present a new gas-grain chemical code for interstellar clouds written in pure Python (GGCHEMPY). By combining with the high-performance Python compiler Numba, GGCHEMPY is as efficient as the Fortran-based version. With the…

Astrophysics of Galaxies · Physics 2022-02-02 Jixing Ge