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Related papers: T-Rex: Text-assisted Retrosynthesis Prediction

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ChatGPT has achieved remarkable success in natural language understanding. Considering that recommendation is indeed a conversation between users and the system with items as words, which has similar underlying pattern with ChatGPT, we…

Information Retrieval · Computer Science 2024-04-16 Yabin Zhang , Wenhui Yu , Erhan Zhang , Xu Chen , Lantao Hu , Peng Jiang , Kun Gai

We introduce KiNetX, a fully automated meta-algorithm for the kinetic analysis of complex chemical reaction networks derived from semi-accurate but efficient electronic structure calculations. It is designed to (i) accelerate the automated…

Chemical Physics · Physics 2019-01-11 Jonny Proppe , Markus Reiher

ChatGPT, as a recently launched large language model (LLM), has shown superior performance in various natural language processing (NLP) tasks. However, two major limitations hinder its potential applications: (1) the inflexibility of…

Computation and Language · Computer Science 2023-09-20 Yucheng Shi , Hehuan Ma , Wenliang Zhong , Qiaoyu Tan , Gengchen Mai , Xiang Li , Tianming Liu , Junzhou Huang

Retrosynthesis strategically plans the synthesis of a chemical target compound from simpler, readily available precursor compounds. This process is critical for synthesizing novel inorganic materials, yet traditional methods in inorganic…

Retrosynthesis is a problem to infer reactant compounds to synthesize a given product compound through chemical reactions. Recent studies on retrosynthesis focus on proposing more sophisticated prediction models, but the dataset to feed the…

Machine Learning · Computer Science 2020-10-05 Katsuhiko Ishiguro , Kazuya Ujihara , Ryohto Sawada , Hirotaka Akita , Masaaki Kotera

Graph generation is a critical task in numerous domains, including molecular design and social network analysis, due to its ability to model complex relationships and structured data. While most modern graph generative models utilize…

Machine Learning · Computer Science 2025-06-04 Xiaohui Chen , Yinkai Wang , Jiaxing He , Yuanqi Du , Soha Hassoun , Xiaolin Xu , Li-Ping Liu

Predicting click-through rates (CTR) is a fundamental task for Web applications, where a key issue is to devise effective models for feature interactions. Current methodologies predominantly concentrate on modeling feature interactions…

Information Retrieval · Computer Science 2024-04-08 Yushen Li , Jinpeng Wang , Tao Dai , Jieming Zhu , Jun Yuan , Rui Zhang , Shu-Tao Xia

Text-to-image synthesis has recently seen significant progress thanks to large pretrained language models, large-scale training data, and the introduction of scalable model families such as diffusion and autoregressive models. However, the…

Machine Learning · Computer Science 2023-01-24 Axel Sauer , Tero Karras , Samuli Laine , Andreas Geiger , Timo Aila

Enzyme-reaction retrieval is a fundamental problem in computational biology, underpinning enzyme characterization, reaction mechanism elucidation, and the rational design of metabolic pathways and biocatalysts. As a bidirectional task, it…

Artificial Intelligence · Computer Science 2026-05-26 Yuhang Zhang , Keyan Ding , Peilin Chen , Han Liu , Can Lin , Ruixi Chen , Shiqi Wang , Qi Song

Causality is fundamental in human cognition and has drawn attention in diverse research fields. With growing volumes of textual data, discerning causalities within text data is crucial, and causal text mining plays a pivotal role in…

Computation and Language · Computer Science 2024-02-26 Takehiro Takayanagi , Masahiro Suzuki , Ryotaro Kobayashi , Hiroki Sakaji , Kiyoshi Izumi

The goal of text ranking is to generate an ordered list of texts retrieved from a corpus in response to a query. Although the most common formulation of text ranking is search, instances of the task can also be found in many natural…

Information Retrieval · Computer Science 2021-08-20 Jimmy Lin , Rodrigo Nogueira , Andrew Yates

Stochastic process-based molecular graph generators have become the state of the art for template-free single-step retrosynthesis. However, these models are typically trained only on product-reactant pairs, thereby acquiring…

Machine Learning · Computer Science 2026-05-26 Jiahai Huang , Anjie Qiao , Zhen Wang , Defu Lian , Yutong Lu

Online grocery shopping presents unique challenges for sequential recommendations due to repetitive purchase patterns and complex item relationships within the baskets. Unlike traditional e-commerce, grocery recommendations must capture…

Information Retrieval · Computer Science 2026-03-10 Soroush Mokhtari , Muhammad Tayyab Asif , Sergiy Zubatiy

Retrosynthesis, the process of breaking down a target molecule into simpler precursors through a series of valid reactions, stands at the core of organic chemistry and drug development. Although recent machine learning (ML) research has…

Artificial Intelligence · Computer Science 2026-05-12 Haorui Wang , Jeff Guo , Lingkai Kong , Rampi Ramprasad , Philippe Schwaller , Yuanqi Du , Chao Zhang

Recent AI research plots a promising future of automatic chemical reactions within the chemistry society. This study proposes Chemist-X, a comprehensive AI agent that automates the reaction condition optimization (RCO) task in chemical…

ChatGPT is a generative pretrained transformer language model created using artificial intelligence implemented as chatbot which can provide very detailed responses to a wide variety of questions. As a very contemporary phenomenon, this…

Cryptography and Security · Computer Science 2023-07-14 Sheetal Temara

Retrosynthetic planning is a fundamental problem in chemistry for finding a pathway of reactions to synthesize a target molecule. Recently, search algorithms have shown promising results for solving this problem by using deep neural…

Machine Learning · Computer Science 2021-06-10 Junsu Kim , Sungsoo Ahn , Hankook Lee , Jinwoo Shin

We have developed an end-to-end, retrosynthesis system, named ChemiRise, that can propose complete retrosynthesis routes for organic compounds rapidly and reliably. The system was trained on a processed patent database of over 3 million…

Chemical Physics · Physics 2021-08-11 Xiangyan Sun , Ke Liu , Yuquan Lin , Lingjie Wu , Haoming Xing , Minghong Gao , Ji Liu , Suocheng Tan , Zekun Ni , Qi Han , Junqiu Wu , Jie Fan

Providing explainable and faithful feedback is crucial for automated student answer assessment. In this paper, we introduce a novel framework that explores using ChatGPT, a cutting-edge large language model, for the concurrent tasks of…

Computation and Language · Computer Science 2023-10-25 Jiazheng Li , Lin Gui , Yuxiang Zhou , David West , Cesare Aloisi , Yulan He

Retrosynthesis prediction is fundamental to drug discovery and chemical synthesis, requiring the identification of reactants that can produce a target molecule. Current template-free methods struggle to capture the structural invariance…

Machine Learning · Computer Science 2025-10-21 Jiaxi Zhuang , Yu Zhang , Aimin Zhou , Ying Qian