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Imbalanced datasets in medical imaging are characterized by skewed class proportions and scarcity of abnormal cases. When trained using such data, models tend to assign higher probabilities to normal cases, leading to biased performance.…

Machine Learning · Computer Science 2023-11-14 Yumnah Hasan , Fatemeh Amerehi , Patrick Healy , Conor Ryan

Early detection of breast cancer is a powerful tool towards decreasing its socioeconomic burden. Although, artificial intelligence (AI) methods have shown remarkable results towards this goal, their "black box" nature hinders their wide…

Machine Learning · Computer Science 2022-02-07 Panagiota Karatza , Kalliopi V. Dalakleidi , Maria Athanasiou , Konstantina S. Nikita

Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Alireza Rezazadeh , Yasamin Jafarian , Ali Kord

Deep learning models have achieved promising results in breast cancer classification, yet their 'black-box' nature raises interpretability concerns. This research addresses the crucial need to gain insights into the decision-making process…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Ann-Kristin Balve , Peter Hendrix

Interpretability is a pressing issue for decision systems. Many post hoc methods have been proposed to explain the predictions of a single machine learning model. However, business processes and decision systems are rarely centered around a…

Machine Learning · Computer Science 2023-03-22 Gianluigi Lopardo , Damien Garreau , Frederic Precioso , Greger Ottosson

Data scarcity and class imbalance are two fundamental challenges in many machine learning applications to healthcare. Breast cancer classification in mammography exemplifies these challenges, with a malignancy rate of around 0.5% in a…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Eric Wu , Kevin Wu , William Lotter

The rapid advancement of generative artificial intelligence has enabled models capable of producing complex textual and visual outputs; however, their decision-making processes remain largely opaque, limiting trust and accountability in…

Artificial Intelligence · Computer Science 2026-02-03 Zeinab Dehghani

Breast cancer remains a leading cause of cancer-related mortality among women worldwide. Ultrasound imaging, widely used due to its safety and cost-effectiveness, plays a key role in early detection, especially in patients with dense breast…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Mohammad Abbadi , Yassine Himeur , Shadi Atalla , Wathiq Mansoor

Several studies indicate that deep learning models can learn to detect breast cancer from mammograms (X-ray images of the breasts). However, challenges with overfitting and poor generalisability prevent their routine use in the clinic.…

Image and Video Processing · Electrical Eng. & Systems 2025-02-05 Emir Ahmed , Spencer A. Thomas , Ciaran Bench

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Yuzhe Lu , Adam Perer

Data-driven fault diagnostics and prognostics suffers from class-imbalance problem in industrial systems and it raises challenges to common machine learning algorithms as it becomes difficult to learn the features of the minority class…

Machine Learning · Computer Science 2018-11-20 Wenfang Lin , Zhenyu Wu , Yang Ji

The application of deep learning models in medical diagnosis has showcased considerable efficacy in recent years. Nevertheless, a notable limitation involves the inherent lack of explainability during decision-making processes. This study…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Konstantinos Pasvantis , Eftychios Protopapadakis

Accurate illness diagnosis is vital for effective treatment and patient safety. Machine learning models are widely used for cancer diagnosis based on historical medical data. However, data imbalance remains a major challenge, leading to…

Machine Learning · Computer Science 2025-03-18 Soufiane Bacha , Huansheng Ning , Belarbi Mostefa , Doreen Sebastian Sarwatt , Sahraoui Dhelim

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

Interpretability is a crucial aspect of machine learning models that enables humans to understand and trust the decision-making process of these models. In many real-world applications, the interpretability of models is essential for legal,…

Machine Learning · Statistics 2023-07-18 Shree Charran R , Sandipan Das Mahapatra

Explainable machine learning (XML) has emerged as a major challenge in artificial intelligence (AI). Although black-box models such as Deep Neural Networks and Gradient Boosting often exhibit exceptional predictive accuracy, their lack of…

Methodology · Statistics 2024-06-18 Evgenii Kuriabov , Jia Li

A novel evolutionary approach for Explainable Artificial Intelligence is presented: the "Evolved Explanations" model (EvEx). This methodology consists in combining Local Interpretable Model Agnostic Explanations (LIME) with Multi-Objective…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Iam Palatnik de Sousa , Marley Maria Bernardes Rebuzzi Vellasco , Eduardo Costa da Silva

Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Model interpretability is an increasingly important component of practical machine learning. Some of the most common forms of interpretability systems are example-based, local, and global explanations. One of the main challenges in…

Machine Learning · Computer Science 2019-01-08 Gregory Plumb , Denali Molitor , Ameet Talwalkar
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