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Three-dimensional inspection of nanostructures such as integrated circuits is important for security and reliability assurance. Two scanning operations are required: ptychographic to recover the complex transmissivity of the specimen; and…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Iksung Kang , Yi Jiang , Mirko Holler , Manuel Guizar-Sicairos , A. F. J. Levi , Jeffrey Klug , Stefan Vogt , George Barbastathis

Ultrasound Localization Microscopy (ULM) has recently enabled the mapping of the cerebral vasculature in vivo with a resolution ten times smaller than the wavelength used, down to ten microns. However, with frame rates up to 20.000 frames…

Medical Physics · Physics 2023-10-23 Erwan Hardy , Jonathan Poree , Hatim Belgharbi , Chloe Bourquin , Frederic Lesage , Jean Provost

This paper presents novel single and multi-shell sampling schemes for diffusion MRI. In diffusion MRI, it is paramount that the number of samples is as small as possible in order that scan times are practical in a clinical setting. The…

Signal Processing · Electrical Eng. & Systems 2019-02-01 Alice P. Bates , Zubair Khalid , Jason D. McEwen , Rodney A. Kennedy , Alessandro Daducci , Erick J. Canales-Rodríguez

Scanning transmission electron microscopy is a common tool used to study the atomic structure of materials. It is an inherently multimodal tool allowing for the simultaneous acquisition of multiple information channels. Despite its…

Tomographic imaging is in general an ill-posed inverse problem. Typically, a single regularized image estimate of the sought-after object is obtained from tomographic measurements. However, there may be multiple objects that are all…

Image and Video Processing · Electrical Eng. & Systems 2022-07-28 Sayantan Bhadra , Umberto Villa , Mark A. Anastasio

Understanding the connectivity in the brain is an important prerequisite for understanding how the brain processes information. In the Brain/MINDS project, a connectivity study on marmoset brains uses two-photon microscopy fluorescence…

A well-known diagnostic imaging modality, termed ultrasound tomography, was quickly developed for the detection of very small tumors whose sizes are smaller than the wavelength of the incident pressure wave without ionizing radiation,…

Medical Physics · Physics 2015-08-05 Tran Quang-Huy , Tran Duc-Tan , Huynh Huu Tue , Nguyen Linh-Trung

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Jinwei Zhang , Lianrui Zuo , Yihao Liu , Samuel Remedios , Bennett A. Landman , Jerry L. Prince , Aaron Carass

In this work, we develop a novel technique for reconstructing images from projection-based nano- and microtomography. Our contribution focuses on enhancing reconstruction quality, particularly for specimen composed of homogeneous material…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Anuraag Mishra , Andrea Gilch , Benjamin Apeleo Zubiri , Jan Rolfes , Frauke Liers

The analysis of secondary quantitative data extracted from high-resolution synchrotron X-ray computed tomography scans represents a significant challenge for users. While a number of methods have been introduced for processing large…

Human-Computer Interaction · Computer Science 2025-05-16 Anja Heim , Thomas Lang , Christoph Heinzl

Current high-resolution imaging techniques require an intact sample that preserves spatial relationships. We here present a novel approach, "puzzle imaging," that allows imaging a spatially scrambled sample. This technique takes many…

Neurons and Cognition · Quantitative Biology 2016-02-17 Joshua I. Glaser , Bradley M. Zamft , George M. Church , Konrad P. Kording

Recent advancements in deep learning for automated image processing and classification have accelerated many new applications for medical image analysis. However, most deep learning applications have been developed using reconstructed,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Hyunkwang Lee , Chao Huang , Sehyo Yune , Shahein H. Tajmir , Myeongchan Kim , Synho Do

Strong-lensing images provide a wealth of information both about the magnified source and about the dark matter distribution in the lens. Precision analyses of these images can be used to constrain the nature of dark matter. However, this…

Instrumentation and Methods for Astrophysics · Physics 2022-05-25 Konstantin Karchev , Adam Coogan , Christoph Weniger

Reliable MRI defacing techniques to safeguard patient privacy while preserving brain anatomy are critical for research collaboration. Existing methods often struggle with incomplete defacing or degradation of brain tissue regions. We…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Lorena Garcia-Foncillas Macias , Aaron Kujawa , Aya Elshalakany , Jonathan Shapey , Tom Vercauteren

Automatic and reliable quantitative tools for MR brain image analysis are a very valuable resources for both clinical and research environments. In the last years, this field has experienced many advances with successful techniques based on…

High-throughput imaging workflows, such as Parallel Rapid Imaging with Spectroscopic Mapping (PRISM), generate data at rates that exceed conventional real-time processing capabilities. We present a scalable FPGA-based preprocessing pipeline…

Hardware Architecture · Computer Science 2025-11-26 Weichien Liao

High quality scanning transmission electron microscopy (STEM) data acquisition and analysis has become increasingly important due to the commercial demand for investigating the properties of complex materials such as battery cathodes;…

X-ray computed tomography is a commonly used technique for noninvasive imaging at synchrotron facilities. Iterative tomographic reconstruction algorithms are often preferred for recovering high quality 3D volumetric images from 2D X-ray…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-16 Mert Hidayetoglu , Tekin Bicer , Simon Garcia de Gonzalo , Bin Ren , Vincent De Andrade , Doga Gursoy , Raj Kettimuthu , Ian T. Foster , Wen-mei W. Hwu

Imaging methods used in modern neuroscience experiments are quickly producing large amounts of data capable of providing increasing amounts of knowledge about neuroanatomy and function. A great deal of information in these datasets is…

Quantitative Methods · Quantitative Biology 2017-01-25 William Gray Roncal , Eva L Dyer , Doga Gürsoy , Konrad Kording , Narayanan Kasthuri

In this paper we present a generalized Deep Learning-based approach for solving ill-posed large-scale inverse problems occuring in medical image reconstruction. Recently, Deep Learning methods using iterative neural networks and cascaded…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Andreas Kofler , Markus Haltmeier , Tobias Schaeffter , Marc Kachelrieß , Marc Dewey , Christian Wald , Christoph Kolbitsch