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Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

Quantitative Methods · Quantitative Biology 2018-08-07 Mayssa Soussia , Islem Rekik

Vision Transformers (ViTs) have achieved state-of-the-art performance in image classification, yet their attention mechanisms often remain opaque and exhibit dense, non-structured behaviors. In this work, we adapt our previously proposed…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Vasileios Arampatzakis , George Pavlidis , Nikolaos Mitianoudis , Nikos Papamarkos

Prognostic modeling is essential for forecasting future clinical scores and enabling early detection of Alzheimers disease (AD). While most existing methods focus on predicting the ADAS-Cog global score, they often overlook the predictive…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Nur Amirah Abd Hamid , Mohd Ibrahim Shapiai , Daphne Teck Ching Lai

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Alzheimer diseases (ADs) involves cognitive decline and abnormal brain protein accumulation, necessitating timely diagnosis for effective treatment. Therefore, CAD systems leveraging deep learning advancements have demonstrated success in…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Saddam Hussain Khan

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…

Vision Transformers (ViTs) achieve state-of-the-art segmentation accuracy but require large training datasets because each layer has unique parameters that must be learned independently. We present RD-ViT, a Recurrent-Depth Vision…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Renjie He

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing brain age with respect to chronological age can reflect increased vulnerability to neurodegeneration and cognitive…

Quantitative Methods · Quantitative Biology 2024-02-13 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Automation of brain tumors in 3D magnetic resonance images (MRIs) is key to assess the diagnostic and treatment of the disease. In recent years, convolutional neural networks (CNNs) have shown improved results in the task. However, high…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Laura Mora Ballestar , Veronica Vilaplana

Alzheimer's disease is a progressive neurodegenerative disorder in which mild cognitive impairment (MCI) marks a critical transition between aging and dementia. Neuroimaging modalities, such as structural MRI, provide biomarkers of this…

Machine Learning · Computer Science 2026-03-02 Vrushank Ahire , Yogesh Kumar , Anouck Girard , M. A. Ganaie

The Vision Transformer (ViT) architecture has established its place in computer vision literature, however, training ViTs for RGB-D object recognition remains an understudied topic, viewed in recent literature only through the lens of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 Georgios Tziafas , Hamidreza Kasaei

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Glioblastoma is a highly aggressive and malignant brain tumor type that requires early diagnosis and prompt intervention. Due to its heterogeneity in appearance, developing automated detection approaches is challenging. To address this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Ziya Ata Yazıcı , İlkay Öksüz , Hazım Kemal Ekenel

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

Vision Transformer (ViT) has demonstrated promising performance in computer vision tasks, comparable to state-of-the-art neural networks. Yet, this new type of deep neural network architecture is vulnerable to adversarial attacks limiting…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Shashank Kotyan , Danilo Vasconcellos Vargas

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Although Vision Transformers (ViTs) have recently demonstrated superior performance in medical imaging problems, they face explainability issues similar to previous architectures such as convolutional neural networks. Recent research…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Minjae Chung , Jong Bum Won , Ganghyun Kim , Yujin Kim , Utku Ozbulak

Sophisticated visualization tools are essential for the presentation and exploration of human neuroimaging data. While two-dimensional orthogonal views of neuroimaging data are conventionally used to display activity and statistical…

Age prediction is an important part of medical assessments and research. It can aid in detecting diseases as well as abnormal ageing by highlighting potential discrepancies between chronological and biological age. To improve understanding…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Sophie Starck , Yadunandan Vivekanand Kini , Jessica Johanna Maria Ritter , Rickmer Braren , Daniel Rueckert , Tamara Mueller

The aging population of the U.S. drives the prevalence of Alzheimer's disease. Brookmeyer et al. forecasts approximately 15 million Americans will have either clinical AD or mild cognitive impairment by 2060. In response to this urgent…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Long Chen , Liben Chen , Binfeng Xu , Wenxin Zhang , Narges Razavian