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Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Nathaniel Putera , Daniel Vilet Rodríguez , Noah Videcrantz , Julia Machnio , Mostafa Mehdipour Ghazi

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

Alzheimer's disease (AD) confirmation often relies on positron emission tomography (PET) or cerebrospinal fluid (CSF) analysis, which are costly and invasive. Consequently, structural MRI biomarkers such as cortical thickness (CT) are…

Computer Vision and Pattern Recognition · Computer Science 2026-04-17 Geonwoo Baek , David H. Salat , Ikbeom Jang

Vision Transformer (ViT) is a pioneering deep learning framework that can address real-world computer vision issues, such as image classification and object recognition. Importantly, ViTs are proven to outperform traditional deep learning…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Yuda Bi , Anees Abrol , Zening Fu , Vince Calhoun

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

To address the problem of medical image recognition, computer vision techniques like convolutional neural networks (CNN) are frequently used. Recently, 3D CNN-based models dominate the field of magnetic resonance image (MRI) analytics. Due…

Computer Vision and Pattern Recognition · Computer Science 2023-02-27 Yuxuan Zhang , Qingzhong Wang , Jiang Bian , Yi Liu , Yanwu Xu , Dejing Dou , Haoyi Xiong

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing \textit{brain age gap} characterized by an elevated brain age relative to the chronological age can reflect…

Machine Learning · Computer Science 2025-01-06 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Alzheimer's disease (AD) is the main cause of dementia which is accompanied by loss of memory and may lead to severe consequences in peoples' everyday life if not diagnosed on time. Very few works have exploited transformer-based networks…

Computation and Language · Computer Science 2022-08-15 Loukas Ilias , Dimitris Askounis

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

Image and Video Processing · Electrical Eng. & Systems 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

We present brat (brain report alignment transformer), a multi-view representation learning framework for brain magnetic resonance imaging (MRI) trained on MRIs paired with clinical reports. Brain MRIs present unique challenges due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Maxime Kayser , Maksim Gridnev , Wanting Wang , Max Bain , Aneesh Rangnekar , Avijit Chatterjee , Aleksandr Petrov , Harini Veeraraghavan , Nathaniel C. Swinburne

Gliomas are the most common and aggressive among brain tumors, which cause a short life expectancy in their highest grade. Therefore, treatment assessment is a key stage to enhance the quality of the patients' lives. Recently, deep…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Mehrdad Noori , Ali Bahri , Karim Mohammadi

In the recent years there have been a number of studies that applied deep learning algorithms to neuroimaging data. Pipelines used in those studies mostly require multiple processing steps for feature extraction, although modern…

Computer Vision and Pattern Recognition · Computer Science 2017-01-25 Sergey Korolev , Amir Safiullin , Mikhail Belyaev , Yulia Dodonova

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante

Most face identification approaches employ a Siamese neural network to compare two images at the image embedding level. Yet, this technique can be subject to occlusion (e.g. faces with masks or sunglasses) and out-of-distribution data.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Hai Phan , Cindy Le , Vu Le , Yihui He , Anh Totti Nguyen

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang

Multimodal neuroimaging provides complementary structural and functional insights into both human brain organization and disease-related dynamics. Recent studies demonstrate enhanced diagnostic sensitivity for Alzheimer's disease (AD)…

Multimedia · Computer Science 2025-04-24 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

In the realm of medical diagnostics, rapid advancements in Artificial Intelligence (AI) have significantly yielded remarkable improvements in brain tumor segmentation. Encoder-Decoder architectures, such as U-Net, have played a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Eyad Gad , Seif Soliman , M. Saeed Darweesh

Biomedical image classification requires capturing of bio-informatics based on specific feature distribution. In most of such applications, there are mainly challenges due to limited availability of samples for diseased cases and imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Arun K. Sharma , Nishchal K. Verma

Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li