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Diffusion models are known for generating high-quality images, causing serious security concerns. To combat this, most efforts rely on deep neural networks (e.g., CNNs and Transformers), while largely overlooking the potential of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Mengxin Fu , Yuezun Li

The discovery and study of new material systems rely on molecular simulations that often come with significant computational expense. We propose MDDM, a Molecular Dynamics Diffusion Model, which is capable of predicting a valid output…

Machine Learning · Computer Science 2025-09-11 Kevin Ferguson , Yu-hsuan Chen , Levent Burak Kara

Most real-world networks are noisy and incomplete samples from an unknown target distribution. Refining them by correcting corruptions or inferring unobserved regions typically improves downstream performance. Inspired by the impressive…

Metal-organic frameworks (MOFs) are of immense interest in applications such as gas storage and carbon capture due to their exceptional porosity and tunable chemistry. Their modular nature has enabled the use of template-based methods to…

Chemical Physics · Physics 2023-10-19 Xiang Fu , Tian Xie , Andrew S. Rosen , Tommi Jaakkola , Jake Smith

Developing generative models to create or conditionally create symbolic music presents unique challenges due to the combination of limited data availability and the need for high precision in note pitch. To address these challenges, we…

Sound · Computer Science 2025-06-09 Tingyu Zhu , Haoyu Liu , Ziyu Wang , Zhimin Jiang , Zeyu Zheng

Nuclear Magnetic Resonance (NMR) spectroscopy is a central characterization method for molecular structure elucidation, yet interpreting NMR spectra to deduce molecular structures remains challenging due to the complexity of spectral data…

Chemical Physics · Physics 2025-07-15 Qingsong Yang , Binglan Wu , Xuwei Liu , Bo Chen , Wei Li , Gen Long , Xin Chen , Mingjun Xiao

This work introduces DiGress, a discrete denoising diffusion model for generating graphs with categorical node and edge attributes. Our model utilizes a discrete diffusion process that progressively edits graphs with noise, through the…

Machine Learning · Computer Science 2023-05-24 Clement Vignac , Igor Krawczuk , Antoine Siraudin , Bohan Wang , Volkan Cevher , Pascal Frossard

Deep generative diffusion models are a promising avenue for 3D de novo molecular design in materials science and drug discovery. However, their utility is still limited by suboptimal performance on large molecular structures and limited…

Machine Learning · Computer Science 2023-11-27 Tuan Le , Julian Cremer , Frank Noé , Djork-Arné Clevert , Kristof Schütt

Transfer learning has gained significant attention in recent deep learning research due to its ability to accelerate convergence and enhance performance on new tasks. However, its success is often contingent on the similarity between source…

Machine Learning · Computer Science 2024-10-28 Bedionita Soro , Bruno Andreis , Hayeon Lee , Wonyong Jeong , Song Chong , Frank Hutter , Sung Ju Hwang

The discovery of new molecules based on the original chemical molecule distributions is of great importance in medicine. The graph transformer, with its advantages of high performance and scalability compared to traditional graph networks,…

Machine Learning · Computer Science 2025-04-30 Ji Shi , Chengxun Xie , Zhonghao Li , Xinming Zhang , Miao Zhang

Diffusion models are at the vanguard of generative AI research with renowned solutions such as ImageGen by Google Brain and DALL.E 3 by OpenAI. Nevertheless, the potential merits of diffusion models for communication engineering…

Information Theory · Computer Science 2023-11-17 Mehdi Letafati , Samad Ali , Matti Latva-aho

Although the recent rapid evolution of 3D generative neural networks greatly improves 3D shape generation, it is still not convenient for ordinary users to create 3D shapes and control the local geometry of generated shapes. To address…

Computer Vision and Pattern Recognition · Computer Science 2023-05-10 Xin-Yang Zheng , Hao Pan , Peng-Shuai Wang , Xin Tong , Yang Liu , Heung-Yeung Shum

Generative models have the potential to accelerate key steps in the discovery of novel molecular therapeutics and materials. Diffusion models have recently emerged as a powerful approach, excelling at unconditional sample generation and,…

Biomolecules · Quantitative Biology 2024-07-17 Leo Klarner , Tim G. J. Rudner , Garrett M. Morris , Charlotte M. Deane , Yee Whye Teh

We introduce the Fixed Point Diffusion Model (FPDM), a novel approach to image generation that integrates the concept of fixed point solving into the framework of diffusion-based generative modeling. Our approach embeds an implicit fixed…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Xingjian Bai , Luke Melas-Kyriazi

Current approaches for modeling discrete-valued outcomes associated with spatially-dependent areal units incur computational and theoretical challenges, especially in the Bayesian setting when full posterior inference is desired. As an…

Methodology · Statistics 2025-05-22 J. Brandon Carter , Catherine A. Calder

Digital Terrain Models (DTMs) represent the bare-earth elevation and are important in numerous geospatial applications. Such data models cannot be directly measured by sensors and are typically generated from Digital Surface Models (DSMs)…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Oussema Dhaouadi , Johannes Meier , Jacques Kaiser , Daniel Cremers

This work discusses the application of an affine reconstructed nodal DG method for unstructured grids of triangles. Solving the diffusion terms in the DG method is non-trivial due to the solution representations being piecewise continuous.…

Computational Physics · Physics 2021-04-20 Yang Song , Bhuvana Srinivasan

Guided or controlled data generation with diffusion models\blfootnote{Partial preliminary results of this work appeared in International Conference on Machine Learning 2025 \citep{li2025provable}.} has become a cornerstone of modern…

Machine Learning · Statistics 2025-12-05 Yuchen Jiao , Yuxin Chen , Gen Li

Diffusion models, a family of generative models based on deep learning, have become increasingly prominent in cutting-edge machine learning research. With a distinguished performance in generating samples that resemble the observed data,…

Machine Learning · Computer Science 2023-05-02 Lequan Lin , Zhengkun Li , Ruikun Li , Xuliang Li , Junbin Gao

Deep generative models have garnered significant attention in low-level vision tasks due to their generative capabilities. Among them, diffusion model-based solutions, characterized by a forward diffusion process and a reverse denoising…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Chunming He , Yuqi Shen , Chengyu Fang , Fengyang Xiao , Longxiang Tang , Yulun Zhang , Wangmeng Zuo , Zhenhua Guo , Xiu Li
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