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Genome Wide Association Studies (GWAS) are used to identify statistically significant genetic variants in case-control studies. GWAS typically use a p-value threshold of 5 x 10-8 to identify highly ranked single nucleotide polymorphisms…

Computational Engineering, Finance, and Science · Computer Science 2018-01-10 Paul Fergus , Casimiro Curbelo Montanez , Basma Abdulaimma , Paulo Lisboa , Carl Chalmers

Accurate screening of cancer types is crucial for effective cancer detection and precise treatment selection. However, the association between gene expression profiles and tumors is often limited to a small number of biomarker genes. While…

Neural and Evolutionary Computing · Computer Science 2024-04-09 Xubin Wang , Yunhe Wang , Zhiqing Ma , Ka-Chun Wong , Xiangtao Li

Due to the high mutation rate of the virus, the COVID-19 pandemic evolved rapidly. Certain variants of the virus, such as Delta and Omicron, emerged with altered viral properties leading to severe transmission and death rates. These…

Other Quantitative Biology · Quantitative Biology 2023-05-29 Rohitash Chandra , Chaarvi Bansal , Mingyue Kang , Tom Blau , Vinti Agarwal , Pranjal Singh , Laurence O. W. Wilson , Seshadri Vasan

Expressive human pose and shape estimation (EHPS) is crucial for digital human generation, especially in applications like live streaming. While existing research primarily focuses on reducing estimation errors, it largely neglects…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhiying Li , Yeying Jin , Fan Shen , Zhi Liu , Weibin Chen , Pengju Zhang , Xiaomei Zhang , Boyu Chen , Michael Shen , Kejian Wu , Zhaoxin Fan , Jin Dong

Designing evolutionary algorithms capable of uncovering highly evolvable representations is an open challenge; such evolvability is important because it accelerates evolution and enables fast adaptation to changing circumstances. This paper…

Neural and Evolutionary Computing · Computer Science 2019-07-16 Alexander Gajewski , Jeff Clune , Kenneth O. Stanley , Joel Lehman

In this work, we have concentrated our efforts on the interpretability of classification results coming from a fully convolutional neural network. Motivated by the classification of oesophageal tissue for real-time detection of early…

Sepsis, a critical condition from the body's response to infection, poses a major global health crisis affecting all age groups. Timely detection and intervention are crucial for reducing healthcare expenses and improving patient outcomes.…

Machine Learning · Computer Science 2024-07-12 MohammadAmin Ansari Khoushabar , Parviz Ghafariasl

One of the common human diseases is sleep disorders. The classification of sleep stages plays a fundamental role in diagnosing sleep disorders, monitoring treatment effectiveness, and understanding the relationship between sleep stages and…

Signal Processing · Electrical Eng. & Systems 2023-10-09 Hassan Ardeshir , Mohammad Araghi

The present research tackles the difficulty of predicting osteoporosis risk via machine learning (ML) approaches, emphasizing the use of explainable artificial intelligence (XAI) to improve model transparency. Osteoporosis is a significant…

Machine Learning · Computer Science 2025-10-03 Farhana Elias , Md Shihab Reza , Muhammad Zawad Mahmud , Samiha Islam , Shahran Rahman Alve

The article proposes a conceptual approach for evaluating the impact of engineered nanoparticles (NPs) on the functionality of small biomolecules. The developed machine learning (ML) model is based on in-silico 13C NMR spectroscopy chemical…

Other Quantitative Biology · Quantitative Biology 2026-03-23 Mariya L Ivanova , Michael Nichols , Nicola Russo , Gueorgui Mihaylov , Konstantin Nikolic

An Event-Related Potential (ERP)-based Brain-Computer Interface (BCI) Speller System assists people with disabilities to communicate by decoding electroencephalogram (EEG) signals. A P300-ERP embedded in EEG signals arises in response to a…

Applications · Statistics 2026-02-18 Tianwen Ma , Jane E. Huggins , Jian Kang

This study explores the application of machine learning-based genetic linguistics for identifying heavy metal response genes in rice (Oryza sativa). By integrating convolutional neural networks and random forest algorithms, we developed a…

Machine Learning · Computer Science 2025-03-24 Ruiqi Yang , Jianxu Wang , Wei Yuan , Xun Wang , Mei Li

This study evaluates the use of Near-Infrared spectroscopy (NIRS) combined with advanced machine learning (ML) techniques to differentiate Hanwoo beef (HNB) and Holstein beef (HLB) to address food authenticity, mislabeling, and…

Machine Learning · Computer Science 2025-07-23 AMM Nurul Alam , Abdul Samad , AMM Shamsul Alam , Jahan Ara Monti , Ayesha Muazzam

In the context of Epidemic Intelligence, many Event-Based Surveillance (EBS) systems have been proposed in the literature to promote the early identification and characterization of potential health threats from online sources of any…

Information Retrieval · Computer Science 2023-03-31 Nejat Arinik , Roberto Interdonato , Mathieu Roche , Maguelonne Teisseire

Existing machine learning methods for molecular (e.g., gene) embeddings are restricted to specific tasks or data modalities, limiting their effectiveness within narrow domains. As a result, they fail to capture the full breadth of gene…

General movement assessment (GMA) of infant movement videos (IMVs) is an effective method for early detection of cerebral palsy (CP) in infants. We demonstrate in this paper that end-to-end trainable neural networks for image sequence…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Haomiao Ni , Yuan Xue , Liya Ma , Qian Zhang , Xiaoye Li , Xiaolei Huang

Effective data selection is essential for pretraining large language models (LLMs), enhancing efficiency and improving generalization to downstream tasks. However, existing approaches often require leveraging external pretrained models,…

Machine Learning · Computer Science 2026-02-04 Jie Hao , Rui Yu , Wei Zhang , Huixia Wang , Jie Xu , Mingrui Liu

The design and deployment of fifth-generation (5G) wireless networks pose significant challenges due to the increasing number of wireless devices. Path loss has a landmark importance in network performance optimization, and accurate…

Machine Learning · Computer Science 2023-10-03 Ibrahim Yazıcı , Emre Gures

Mutations sometimes increase contagiousness for evolving pathogens. During an epidemic, scientists use viral genome data to infer a shared evolutionary history and connect this history to geographic spread. We propose a model that directly…

Populations and Evolution · Quantitative Biology 2021-09-14 Andrew J. Holbrook , Xiang Ji , Marc A. Suchard