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The brain is a system operating on multiple time scales, and characterisation of dynamics across time scales remains a challenge. One framework to study such dynamics is that of fractal geometry. However, currently there exists no…

Neurons and Cognition · Quantitative Biology 2018-12-12 Lucas G. S. França , José G. V. Miranda , Marco Leite , Niraj K. Sharma , Matthew C. Walker , Louis Lemieux , Yujiang Wang

Background: Any treatment of multiple sclerosis should preserve mental function, considering how cognitive deterioration interferes with quality of life. However, mental assessment is still realized with neuro-psychological tests without…

Subcortical structures play a critical role in brain function. However, options for assessing electrophysiological activity in these structures are limited. Electromagnetic fields generated by neuronal activity in subcortical structures can…

Multiple Sclerosis (MS) is a chronic disease developed in human brain and spinal cord, which can cause permanent damage or deterioration of the nerves. The severity of MS disease is monitored by the Expanded Disability Status Scale (EDSS),…

Machine Learning · Computer Science 2023-04-11 Kai Zhang , John A. Lincoln , Xiaoqian Jiang , Elmer V. Bernstam , Shayan Shams

We calculate a measure of statistical complexity from the global dynamics of electroencephalographic (EEG) signals from healthy subjects and epileptic patients, and are able to stablish a criterion to characterize the collective behavior in…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 M. Escalona-Moran , M. G. Cosenza , R. Lopez-Ruiz , P. Garcia

The neuromagnetic activity (magnetoencephalogram, MEG) from healthy human brain and from an epileptic patient against chromatic flickering stimuli has been earlier analyzed on the basis of a memory functions formalism (MFF). Information…

Medical Physics · Physics 2010-06-29 O. Yu. Panischev , S. A. Demin , J. Bhattacharya

Multiple Sclerosis (MS) is a chronic disease characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, and cognitive). Predicting disease progression with a probabilistic and time-dependent…

High temporal resolution measurements of human brain activity can be performed by recording the electric potentials on the scalp surface (electroencephalography, EEG), or by recording the magnetic fields near the surface of the head…

Data Analysis, Statistics and Probability · Physics 2015-01-22 Kevin H. Knuth

Complex network analysis has an increasing relevance in the study of neurological disorders, enhancing the knowledge of brain's structural and functional organization. Network structure and efficiency reveal different brain states along…

Neurons and Cognition · Quantitative Biology 2022-01-24 Nicolás J. Gallego-Molina , Andrés Ortiz , Francisco J. Martínez-Murcia , Marco Formoso , Almudena Giménez

Electroencephalogram (EEG) is a common tool used to understand brain activities. The data are typically obtained by placing electrodes at the surface of the scalp and recording the oscillations of currents passing through the electrodes.…

Signal Processing · Electrical Eng. & Systems 2021-02-19 Eddy Kwessi , Lloyd Edwards

Brain function as measured by multichannel EEG recordings can be described to a high level of accuracy by microstates, characterized as a sequence of time intervals within which the sign invariant normalized scalp electric potential field…

Neurons and Cognition · Quantitative Biology 2022-08-08 Roberto D. Pascual-Marqui , Kieko Kochi , Toshihiko Kinoshita

Clinical electroencephalography is routinely used to evaluate patients with diverse and often overlapping neurological conditions, yet interpretation remains manual, time-intensive, and variable across experts. While automated EEG analysis…

Human-Computer Interaction · Computer Science 2025-12-30 Argha Kamal Samanta , Deepak Mewada , Monalisa Sarma , Debasis Samanta

The brain is a complex system whose understanding enables potentially deeper approaches to mental phenomena. Dynamics of wide classes of complex systems have been satisfactorily described within $q$-statistics, a current generalization of…

Neurons and Cognition · Quantitative Biology 2023-08-15 Dimitri Marques Abramov , Constantino Tsallis , Henrique Santos Lima

The prospects of assessing neural complexity (NC) by $q$-statistics of the systemic organization of different types and levels of brain activity were studied. In 70 adult subjects, NC was assessed via the parameter $q$ of $q$-statistics,…

Parkinson disease (PD) is marked by progressive neurodegeneration, yet early and subtle structural alterations in brain tissue remain difficult to detect with conventional imaging and analytical methods. Fractal and multifractal frameworks…

Medical Physics · Physics 2025-12-09 Santanu Maity , Mousa Alrubayan , Mohammad Moshahid Khan , Prabhakar Pradhan

Synchronous oscillations of neuronal populations support resting-state cortical activity. Recent studies indicate that resting-state functional connectivity is not static, but exhibits complex dynamics. The mechanisms underlying the complex…

Neurons and Cognition · Quantitative Biology 2020-07-31 Steve Mehrkanoon

Early multiple sclerosis (MS) disability progression prediction is challenging due to disease heterogeneity. This work predicts 48- and 72-week disability using sparse baseline clinical data and 12 weeks of daily digital Floodlight data…

Machine Learning · Computer Science 2025-06-19 Maxime Usdin , Lito Kriara , Licinio Craveiro

Detecting where and when brain regions activate in a cognitive task or in a given clinical condition is the promise of non-invasive techniques like magnetoencephalography (MEG) or electroencephalography (EEG). This problem, referred to as…

Machine Learning · Statistics 2020-11-26 Jérôme-Alexis Chevalier , Alexandre Gramfort , Joseph Salmon , Bertrand Thirion

Electroencephalography (EEG) monitors ---by either intrusive or noninvasive electrodes--- time and frequency variations and spectral content of voltage fluctuations or waves, known as brain rhythms, which in some way uncover activity during…

Neurons and Cognition · Quantitative Biology 2019-03-13 Javier A. Galadí , Joaquín J. Torres , J. Marro

Inferring patterns of synchronous brain activity from a heterogeneous sample of electroencephalograms (EEG) is scientifically and methodologically challenging. While it is intuitively and statistically appealing to rely on readings from…

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