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This paper investigates the application of the transformer architecture in protein folding, as exemplified by DeepMind's AlphaFold project, and its implications for the understanding of so-called large language models. The prevailing…

Computers and Society · Computer Science 2024-12-10 Fabian Offert , Paul Kim , Qiaoyu Cai

Multitask learning is a common approach in machine learning, which allows to train multiple objectives with a shared architecture. It has been shown that by training multiple tasks together inference time and compute resources can be saved,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-13 Falk Heuer , Sven Mantowsky , Syed Saqib Bukhari , Georg Schneider

Recent advancements in Large Language Models (LLMs) have demonstrated exceptional capabilities in natural language understanding and generation. While these models excel in general complex reasoning tasks, they still face challenges in…

Artificial Intelligence · Computer Science 2024-10-25 Graziano A. Manduzio , Federico A. Galatolo , Mario G. C. A. Cimino , Enzo Pasquale Scilingo , Lorenzo Cominelli

Multi-modal Large Language Models (MLLMs) have exhibited impressive capability. However, recently many deficiencies of MLLMs have been found compared to human intelligence, $\textit{e.g.}$, hallucination. To drive the MLLMs study, the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Hong Li , Nanxi Li , Yuanjie Chen , Jianbin Zhu , Qinlu Guo , Cewu Lu , Yong-Lu Li

Scientific knowledge discovery increasingly relies on large language models, yet many existing scholarly assistants depend on proprietary systems with tens or hundreds of billions of parameters. Such reliance limits reproducibility and…

Information Retrieval · Computer Science 2026-04-23 Florian Kelber , Matthias Jobst , Yuni Susanti , Michael Färber

Applications of machine learning in chemistry are often limited by the scarcity and expense of labeled data, restricting traditional supervised methods. In this work, we introduce a framework for molecular reasoning using general-purpose…

Many common character-level, string-to string transduction tasks, e.g., grapheme-tophoneme conversion and morphological inflection, consist almost exclusively of monotonic transductions. However, neural sequence-to sequence models that use…

Computation and Language · Computer Science 2024-02-21 Shijie Wu , Ryan Cotterell

The large transformer-based language models demonstrate excellent performance in natural language processing. By considering the transferability of the knowledge gained by these models in one domain to other related domains, and the…

Cryptography and Security · Computer Science 2022-09-07 Chandra Thapa , Seung Ick Jang , Muhammad Ejaz Ahmed , Seyit Camtepe , Josef Pieprzyk , Surya Nepal

Recent trends in natural language processing research and annotation tasks affirm a paradigm shift from the traditional reliance on a single ground truth to a focus on individual perspectives, particularly in subjective tasks. In scenarios…

Computation and Language · Computer Science 2024-04-18 Olufunke O. Sarumi , Béla Neuendorf , Joan Plepi , Lucie Flek , Jörg Schlötterer , Charles Welch

Embedders play a central role in machine learning, projecting any object into numerical representations that can, in turn, be leveraged to perform various downstream tasks. The evaluation of embedding models typically depends on…

Machine Learning · Computer Science 2024-11-19 Maxime Darrin , Philippe Formont , Ismail Ben Ayed , Jackie CK Cheung , Pablo Piantanida

This paper addresses the limitations of large language models in understanding long-term context. It proposes a model architecture equipped with a long-term memory mechanism to improve the retention and retrieval of semantic information…

Computation and Language · Computer Science 2025-05-30 Yue Xing , Tao Yang , Yijiashun Qi , Minggu Wei , Yu Cheng , Honghui Xin

The genome sequence contains the blueprint for governing cellular processes. While the availability of genomes has vastly increased over the last decades, experimental annotation of the various functional, non-coding and regulatory elements…

Genomics · Quantitative Biology 2024-04-10 Frederikke Isa Marin , Felix Teufel , Marc Horlacher , Dennis Madsen , Dennis Pultz , Ole Winther , Wouter Boomsma

Despite interest in using cross-lingual knowledge to learn word embeddings for various tasks, a systematic comparison of the possible approaches is lacking in the literature. We perform an extensive evaluation of four popular approaches of…

Computation and Language · Computer Science 2016-06-09 Shyam Upadhyay , Manaal Faruqui , Chris Dyer , Dan Roth

Modality following is the ability to selectively leverage multimodal contexts based on user instructions. It is fundamental to the safety and reliability of multimodal large language models (MLLMs) in real-world deployments. However, the…

Computation and Language · Computer Science 2026-05-12 Yu Zhang , Mufan Xu , Xuefeng Bai , Kehai Chen , Pengfei Zhang , Yang Xiang , Min Zhang

Cognitive science faces ongoing challenges in research integration, formalization, conceptual clarity, and other areas, in part due to its multifaceted and interdisciplinary nature. Recent advances in artificial intelligence, particularly…

Artificial Intelligence · Computer Science 2026-03-03 Dirk U. Wulff , Rui Mata

Large Language Models (LLMs) have shown useful applications in a variety of tasks, including data wrangling. In this paper, we investigate the use of an off-the-shelf LLM for schema matching. Our objective is to identify semantic…

Databases · Computer Science 2024-07-17 Marcel Parciak , Brecht Vandevoort , Frank Neven , Liesbet M. Peeters , Stijn Vansummeren

Large language models have demonstrated exceptional performance across multiple crosslingual NLP tasks, including machine translation (MT). However, persistent challenges remain in addressing context-sensitive units (CSUs), such as…

Computation and Language · Computer Science 2025-05-30 Qiuyu Ding , Zhiqiang Cao , Hailong Cao , Tiejun Zhao

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

Intelligent systems must maintain and manipulate task-relevant information online to adapt to dynamic environments and changing goals. This capacity, known as working memory, is fundamental to human reasoning and intelligence. Despite…

Machine Learning · Computer Science 2026-04-14 Hua-Dong Xiong , Li Ji-An , Jiaqi Huang , Robert C. Wilson , Kwonjoon Lee , Xue-Xin Wei

Large Language Models (LLMs) are increasingly deployed in interactive environments requiring strategic decision-making, yet systematic evaluation of these capabilities remains challenging. Existing benchmarks for LLMs primarily assess…

Artificial Intelligence · Computer Science 2026-02-17 Lingfeng Li , Yunlong Lu , Yuefei Zhang , Jingyu Yao , Yixin Zhu , KeYuan Cheng , Yongyi Wang , Qirui Zheng , Xionghui Yang , Wenxin Li