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The spatial location of cells within tissues and organs is crucial for the manifestation of their specific functions.Spatial transcriptomics technology enables comprehensive measurement of the gene expression patterns in tissues while…

Quantitative Methods · Quantitative Biology 2024-07-12 Shuailin Xue , Fangfang Zhu , Changmiao Wang , Wenwen Min

In recent years, the advent of spatial transcriptomics (ST) technology has unlocked unprecedented opportunities for delving into the complexities of gene expression patterns within intricate biological systems. Despite its transformative…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Wenwen Min , Zhiceng Shi , Jun Zhang , Jun Wan , Changmiao Wang

Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…

Quantitative Methods · Quantitative Biology 2026-03-25 Sean Cottrell , Guo-Wei Wei , Longxiu Huang

End-to-end speech translation (ST) is the task of translating speech signals in the source language into text in the target language. As a cross-modal task, end-to-end ST is difficult to train with limited data. Existing methods often try…

Computation and Language · Computer Science 2023-05-26 Yan Zhou , Qingkai Fang , Yang Feng

Spatial Transcriptomics (ST) is a method that captures gene expression profiles aligned with spatial coordinates. The discrete spatial distribution and the super-high dimensional sequencing results make ST data challenging to be modeled…

Machine Learning · Computer Science 2025-05-08 Qingtian Zhu , Yumin Zheng , Yuling Sang , Yifan Zhan , Ziyan Zhu , Jun Ding , Yinqiang Zheng

The rapid advancement of spatial transcriptomics (ST), i.e., spatial gene expressions, has made it possible to measure gene expression within original tissue, enabling us to discover molecular mechanisms. However, current ST platforms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Xiaofei Wang , Stephen Price , Chao Li

Effective management of environmental resources and agricultural sustainability heavily depends on accurate soil moisture data. However, datasets like the SMAP/Sentinel-1 soil moisture product often contain missing values across their…

Machine Learning · Computer Science 2023-12-05 Kehui Yao , Jingyi Huang , Jun Zhu

Multimodal Machine Learning has emerged as a prominent research direction across various applications such as Sentiment Analysis, Emotion Recognition, Machine Translation, Hate Speech Recognition, and Movie Genre Classification. This…

Computation and Language · Computer Science 2023-06-13 Abdelhamid Haouhat , Slimane Bellaouar , Attia Nehar , Hadda Cherroun

Deep learning models such as convolutional neural net- work have been widely used in 3D biomedical segmentation and achieve state-of-the-art performance. However, most of them often adapt a single modality or stack multiple modalities as…

Computer Vision and Pattern Recognition · Computer Science 2017-04-26 Kuan-Lun Tseng , Yen-Liang Lin , Winston Hsu , Chung-Yang Huang

Unpaired medical image synthesis aims to provide complementary information for an accurate clinical diagnostics, and address challenges in obtaining aligned multi-modal medical scans. Transformer-based models excel in imaging translation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Vu Minh Hieu Phan , Yutong Xie , Bowen Zhang , Yuankai Qi , Zhibin Liao , Antonios Perperidis , Son Lam Phung , Johan W. Verjans , Minh-Son To

Contrastive loss has been increasingly used in learning representations from multiple modalities. In the limit, the nature of the contrastive loss encourages modalities to exactly match each other in the latent space. Yet it remains an open…

Machine Learning · Computer Science 2023-03-13 Qian Jiang , Changyou Chen , Han Zhao , Liqun Chen , Qing Ping , Son Dinh Tran , Yi Xu , Belinda Zeng , Trishul Chilimbi

Spatiotemporal learning has become a pivotal technique to enable urban intelligence. Traditional spatiotemporal models mostly focus on a specific task by assuming a same distribution between training and testing sets. However, given that…

Machine Learning · Computer Science 2025-01-16 Zhongchao Yi , Zhengyang Zhou , Qihe Huang , Yanjiang Chen , Liheng Yu , Xu Wang , Yang Wang

Whole slide images (WSIs) enable weakly supervised prognostic modeling via multiple instance learning (MIL). Spatial transcriptomics (ST) preserves in situ gene expression, providing a spatial molecular context that complements morphology.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Lihe Liu , Xiaoxi Pan , Yinyin Yuan , Lulu Shang

Understanding how visual information is encoded in biological and artificial systems often requires vision scientists to generate appropriate stimuli to test specific hypotheses. Although deep neural network models have revolutionized the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Antonino Greco , Markus Siegel

Test-Time Adaptation (TTA) aims to tackle distribution shifts using unlabeled test data without access to the source data. In the context of multimodal data, there are more complex noise patterns than unimodal data such as simultaneous…

Machine Learning · Computer Science 2025-03-05 Zirun Guo , Tao Jin

Spatially Resolved Transcriptomics (SRT) is a cutting-edge technique that captures the spatial context of cells within tissues, enabling the study of complex biological networks. Recent graph-based methods leverage both gene expression and…

Machine Learning · Computer Science 2025-06-24 Yunhak Oh , Junseok Lee , Yeongmin Kim , Sangwoo Seo , Namkyeong Lee , Chanyoung Park

Combining images from multi-modalities is beneficial to explore various information in computer vision, especially in the medical domain. As an essential part of clinical diagnosis, multi-modal brain tumor segmentation aims to delineate the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Zhongzhen Huang , Linda Wei , Shaoting Zhang , Xiaofan Zhang

Multi-modal learning aims to enhance performance by unifying models from various modalities but often faces the "modality imbalance" problem in real data, leading to a bias towards dominant modalities and neglecting others, thereby limiting…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Yang Yang , Hongpeng Pan , Qing-Yuan Jiang , Yi Xu , Jinghui Tang

In this paper, we introduce QuST-LLM, an innovative extension of QuPath that utilizes the capabilities of large language models (LLMs) to analyze and interpret spatial transcriptomics (ST) data. In addition to simplifying the intricate and…

Genomics · Quantitative Biology 2024-07-03 Chao Hui Huang

Monocular 3D object detection is a promising yet ill-posed task for autonomous vehicles due to the lack of accurate depth information. Cross-modality knowledge distillation could effectively transfer depth information from LiDAR to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Rui Ding , Meng Yang , Nanning Zheng
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