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The application of generative models in crystal structure prediction (CSP) has gained significant attention. Conditional generation--particularly the generation of crystal structures with specified stability or other physical properties has…

Materials Science · Physics 2026-01-14 Takanori Ishii , Kaoru Hisama , Kohei Shinohara

Accelerating inverse design of crystalline materials with generative models has significant implications for a range of technologies. Unlike other atomic systems, 3D crystals are invariant to discrete groups of isometries called the space…

Materials Science · Physics 2025-10-27 Rees Chang , Angela Pak , Alex Guerra , Ni Zhan , Nick Richardson , Elif Ertekin , Ryan P. Adams

Machine learning (ML) methods have gained increasing popularity in exploring and developing new materials. More specifically, graph neural network (GNN) has been applied in predicting material properties. In this work, we develop a novel…

Computational Physics · Physics 2020-08-18 Steph-Yves Louis , Yong Zhao , Alireza Nasiri , Xiran Wong , Yuqi Song , Fei Liu , Jianjun Hu

Materials discovery, especially for applications that require extreme operating conditions, requires extensive testing that naturally limits the ability to inquire the wealth of possible compositions. Machine Learning (ML) has nowadays a…

Materials Science · Physics 2023-06-21 Dario Massa , Daniel Cieśliński , Amirhossein Naghdi , Stefanos Papanikolaou

Deep generative diffusion models are a promising avenue for 3D de novo molecular design in materials science and drug discovery. However, their utility is still limited by suboptimal performance on large molecular structures and limited…

Machine Learning · Computer Science 2023-11-27 Tuan Le , Julian Cremer , Frank Noé , Djork-Arné Clevert , Kristof Schütt

In recent years, diffusion-based models have demonstrated exceptional performance in searching for simultaneously stable, unique, and novel (S.U.N.) crystalline materials. However, most of these models don't have the ability to change the…

Machine Learning · Computer Science 2026-05-29 Andrey Okhotin , Maksim Nakhodnov , Nikita Kazeev , Mikhail Lazarev , Andrey E Ustyuzhanin , Dmitry Vetrov

Crystalline materials are a fundamental component in next-generation technologies, yet modeling their distribution presents unique computational challenges. Of the plausible arrangements of atoms in a periodic lattice only a vanishingly…

Machine Learning · Computer Science 2024-06-10 Benjamin Kurt Miller , Ricky T. Q. Chen , Anuroop Sriram , Brandon M Wood

As 3D point clouds become a cornerstone of modern technology, the need for sophisticated generative models and reliable evaluation metrics has grown exponentially. In this work, we first expose that some commonly used metrics for evaluating…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Matteo Bastico , David Ryckelynck , Laurent Corté , Yannick Tillier , Etienne Decencière

Generating molecular structures with desired properties is a critical task with broad applications in drug discovery and materials design. We propose 3M-Diffusion, a novel multi-modal molecular graph generation method, to generate diverse,…

Machine Learning · Computer Science 2024-10-04 Huaisheng Zhu , Teng Xiao , Vasant G Honavar

Recent advances in generative models have inspired the field of recommender systems to explore generative approaches, but most existing research focuses on sequence generation, a paradigm ill-suited for click-through rate (CTR) prediction.…

Information Retrieval · Computer Science 2025-08-28 Moyu Zhang , Yun Chen , Yujun Jin , Jinxin Hu , Yu Zhang

The large amount of powder diffraction data for which the corresponding crystal structures have not yet been identified suggests the existence of numerous undiscovered, physically relevant crystal structure prototypes. In this paper, we…

Materials Science · Physics 2024-10-31 Abhijith S. Parackal , Rhys E. A. Goodall , Felix A. Faber , Rickard Armiento

Diffusion probabilistic models have quickly become a major approach for generative modeling of images, 3D geometry, video and other domains. However, to adapt diffusion generative modeling to these domains the denoising network needs to be…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Peiye Zhuang , Samira Abnar , Jiatao Gu , Alex Schwing , Joshua M. Susskind , Miguel Ángel Bautista

Generative diffusion models apply the concept of Langevin dynamics in physics to machine leaning, attracting a lot of interests from engineering, statistics and physics, but a complete picture about inherent mechanisms is still lacking. In…

Statistical Mechanics · Physics 2025-01-07 Zhendong Yu , Haiping Huang

This paper presents a novel method for analyzing the latent space geometry of generative models, including statistical physics models and diffusion models, by reconstructing the Fisher information metric. The method approximates the…

Machine Learning · Computer Science 2025-06-13 Alexander Lobashev , Dmitry Guskov , Maria Larchenko , Mikhail Tamm

Intracrystalline diffusion is an invaluable tool for estimating timescales of geological events. Diffusion is typically modeled using gradients in chemical potential. However, chemical potential is derived for uniform pressure and…

Materials Science · Physics 2023-06-22 Benjamin L. Hess , Jay J. Ague

Autonomous materials discovery with desired properties is one of the ultimate goals for materials science, and the current studies have been focusing mostly on high-throughput screening based on density functional theory calculations and…

We propose a novel diffusion-based image generation method called the observation-guided diffusion probabilistic model (OGDM), which effectively addresses the tradeoff between quality control and fast sampling. Our approach reestablishes…

Machine Learning · Computer Science 2024-04-02 Junoh Kang , Jinyoung Choi , Sungik Choi , Bohyung Han

Diffusion generative models have excelled at diverse image generation and reconstruction tasks across fields. A less explored avenue is their application to discriminative tasks involving regression or classification problems. The…

Cosmology and Nongalactic Astrophysics · Physics 2025-02-26 Nayantara Mudur , Carolina Cuesta-Lazaro , Douglas P. Finkbeiner

Finding new superconductors with a high critical temperature ($T_c$) has been a challenging task due to computational and experimental costs. We present a diffusion model inspired by the computer vision community to generate new…

Superconductivity · Physics 2023-07-28 Daniel Wines , Tian Xie , Kamal Choudhary

Many particle physics datasets like those generated at colliders are described by continuous coordinates (in contrast to grid points like in an image), respect a number of symmetries (like permutation invariance), and have a stochastic…

High Energy Physics - Phenomenology · Physics 2023-11-03 Vinicius Mikuni , Benjamin Nachman , Mariel Pettee
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