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Prognostic tumor growth modeling via volumetric medical imaging observations can potentially lead to better outcomes of tumor treatment and surgical planning. Recent advances of convolutional networks have demonstrated higher accuracy than…

Computer Vision and Pattern Recognition · Computer Science 2019-09-25 Ling Zhang , Le Lu , Xiaosong Wang , Robert M. Zhu , Mohammadhadi Bagheri , Ronald M. Summers , Jianhua Yao

Non-linear evolution of the parametric instability of inertial waves inherent to eccentric discs is studied by way of a new local numerical model. Mode coupling of tidal deformation with the disc eccentricity is known to produce…

Earth and Planetary Astrophysics · Physics 2018-05-02 Aaron F. Wienkers , Gordon I. Ogilvie

The companion paper "Higher-order in time quasi-unconditionally stable ADI solvers for the compressible Navier-Stokes equations in 2D and 3D curvilinear domains", which is referred to as Part I in what follows, introduces ADI (Alternating…

Computational Physics · Physics 2018-01-11 Oscar Bruno , Max Cubillos

The present paper deals with a free boundary problem modeling the growth process of necrotic multi-layer tumors. We prove the existence of flat stationary solutions and determine the linearization of our model at such an equilibrium.…

Analysis of PDEs · Mathematics 2012-09-18 Martin Kohlmann

In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular…

Mathematical Physics · Physics 2010-11-09 Andrea Tosin

We present a phase-space analysis of a mathematical model of tumor growth with an immune responses. We consider mathematical analysis of the model equations with multipoint initial condition regarding to dissipativity, boundedness of…

Dynamical Systems · Mathematics 2019-02-28 Veli Shakhmurov , Rishad Shahmurov

Physics-informed neural networks have emerged as a powerful tool in the scientific machine learning community, with applications to both forward and inverse problems. While they have shown considerable empirical success, significant…

Optimization and Control · Mathematics 2025-12-11 Federica Caforio , Martin Holler , Matthias Höfler

Owing to their inherently interpretable structure, decision trees are commonly used in applications where interpretability is essential. Recent work has focused on improving various aspects of decision trees, including their predictive…

Machine Learning · Statistics 2023-05-30 Dimitris Bertsimas , Vassilis Digalakis

Cancer is a disease that takes millions of lives every year. Then, to propose treatments, avoid recurrence, and improve the patient's life quality, we need to analyze this disease from a biophysical perspective with a solid mathematical…

Quantitative Methods · Quantitative Biology 2024-07-09 Carlos M. Nieto , Oscar M. Pimentel , Fabio D. Lora-Clavijo

Percolation theory from statistical physics has been applied to several aspects of tumor progression. Tumor growth on percolation clusters has been used to model spatial expansion, vascular percolation to describe nutrient supply and…

Other Quantitative Biology · Quantitative Biology 2026-05-04 Arturo Tozzi

The full non-linear evolution of the tidal instability is studied numerically in an ellipsoidal fluid domain relevant for planetary cores applications. Our numerical model, based on a finite element method, is first validated by reproducing…

Classical Physics · Physics 2010-10-01 David Cébron , Michael Le Bars , Justin Leontini , Pierre Maubert , Patrice Le Gal

The availability of cancer measurements over time enables the personalised assessment of tumour growth and therapeutic response dynamics. However, many tumours are treated after diagnosis without collecting longitudinal data, and cancer…

Analysis of PDEs · Mathematics 2024-04-19 Elena Beretta , Cecilia Cavaterra , Matteo Fornoni , Guillermo Lorenzo , Elisabetta Rocca

In this paper we study a free boundary problem for the growth of multi-layer tumors in necrotic phase. The tumor region is strip-like and divided into necrotic region and proliferating region with two free boundaries. The upper free…

Analysis of PDEs · Mathematics 2019-09-04 Junde Wu

This work studies lung tumor growth prediction from sparse and irregular longitudinal computed tomography (CT) observations with measurement variability. A Bayesian physics-informed neural network is developed by combining Gompertz growth…

Machine Learning · Computer Science 2026-05-14 Lingfei Kong , Haoran Ma

Volumetry is one of the principal downstream applications of 3D medical image segmentation, for example, to detect abnormal tissue growth or for surgery planning. Conformal Prediction is a promising framework for uncertainty quantification,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Benjamin Lambert , Florence Forbes , Senan Doyle , Michel Dojat

The well known nonlinear model for describing the solid tumour growth [Byrne HM., et al. Appl Math Letters 2003;16:567-74] is under study using an approach based on Lie symmetries. It is shown that the model in the two-dimensional (in…

Mathematical Physics · Physics 2021-01-01 Roman Cherniha , Vasyl' Davydovych

Brain-related experiments are limited by nature, and so biological insights are often restricted or absent. This is particularly problematic in the context of brain cancers, which have very poor survival rates. To generate and test new…

Dynamical Systems · Mathematics 2021-08-10 Szabolcs Suveges , Kismet Hossain-Ibrahim , J. Douglas Steele , Raluca Eftimie , Dumitru Trucu

In this paper we consider a free boundary tumor growth model with a time delay in cell proliferation and study how time delay affects the stability and the size of the tumor. The model is a coupled system of an elliptic equation, a…

Analysis of PDEs · Mathematics 2019-08-20 Xinyue Evelyn Zhao , Bei Hu

We propose a diffuse interface model to describe tumor as a multicomponent deformable porous medium. We include mechanical effects in the model by coupling the mass balance equations for the tumor species and the nutrient dynamics to a…

Analysis of PDEs · Mathematics 2021-09-23 Pavel Krejci , Elisabetta Rocca , Juergen Sprekels

We present a numerical stability analysis of the immersed boundary(IB) method for a special case which is constructed so that Fourier analysis is applicable. We examine the stability of the immersed boundary method with the discrete Fourier…

Numerical Analysis · Mathematics 2022-08-10 Mengjian Hua , Charles S. Peskin
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